Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lelia Wolf-van Buerck"'
Autor:
Felix Lindheimer, Magdalena Julia Lindner, Rosel Oos, Mohsen Honarpisheh, Yichen Zhang, Yutian Lei, Lelia Wolf-van Buerck, Franz Josef Gildehaus, Simon Lindner, Peter Bartenstein, Elisabeth Kemter, Eckhard Wolf, Jochen Seissler, Sibylle Ziegler
Publikováno v:
Frontiers in Nuclear Medicine, Vol 3 (2023)
IntroductionIslet xenotransplantation may be a therapeutic option in type 1 diabetes. Recent advances in generating genetically modified source pigs offer advantages as immune suppressants can potentially be eliminated after the transplantation. Ther
Externí odkaz:
https://doaj.org/article/1f7bbbfa24554532ab877a5d7dbb576d
Autor:
Elisabeth Kemter, Antonio Citro, Lelia Wolf‐van Buerck, Yi Qiu, Anika Böttcher, Martina Policardi, Silvia Pellegrini, Libera Valla, Marianna Alunni‐Fabbroni, Julianna Kobolák, Barbara Kessler, Mayuko Kurome, Valeri Zakhartchenko, Andras Dinnyes, Clemens C. Cyran, Heiko Lickert, Lorenzo Piemonti, Jochen Seissler, Eckhard Wolf
Publikováno v:
Xenotransplantation
Xenotransplantation 29:e12719 (2022)
Xenotransplantation 29:e12719 (2022)
BACKGROUND: Islet xenotransplantation is a promising concept for beta-cell replacement therapy. Reporter genes for noninvasive monitoring of islet engraftment, graft mass changes, long-term survival, and graft failure support the optimization of tran
Autor:
Konrad Fischer, Nina Simm, Jochen Seissler, Dirk Wohlleber, Lelia Wolf-van Buerck, Andrea Fischer, K Manske, Angelika Schnieke, Percy A. Knolle
Publikováno v:
Xenotransplantation. 27
BACKGROUND: Ubiquitous expression of T-cell regulatory transgenes such as the cytotoxic T lymphocyte-associated antigen 4 (CTLA4) or the high-affinity variant LEA29Y improves xeno graft survival. Such donor pigs are however immunocompromised and susc
Autor:
Kerstin Maetz-Rensing, Andrea Baehr, Nikolai Klymiuk, M Schuster, Tamara Becker, Yvonne Knauf, Jochen Seissler, Eckhard Wolf, Joachim Denner, Elena Plotzki, Lelia Wolf-van Buerck
Publikováno v:
Virus Research. 204:95-102
Transplantation of pig islet cells for the treatment of diabetes may be a more effective approach compared with the application of insulin. However, before introduction into the clinic, efficacy and safety of this treatment have to be shown. Non-huma
Autor:
Jochen Seissler, Andrea Wolf, Eckhard Wolf, A. Wuensch, Valeri Zakhartchenko, Mayuko Kurome, Yuri Ivashchenko, Barbara Kessler, Matthias Loehn, Stephan Speier, Matthias Schäfer, Anke Schulte, Christian M. Cohrs, Klaus Steinmeyer, Lelia Wolf-van Buerck, M Schuster, Elisabeth Kemter
Publikováno v:
Diabetologia. 60(6)
Autor:
Eckhard Wolf, Jochen Seissler, Sonja Guethoff, M Schuster, Yun-Chung Nam-Apostolopoulos, Andrea Baehr, Bruno Reichart, Lelia Wolf-van Buerck, Tanja Mayr, J.-M. Abicht, Nikolai Klymiuk
Publikováno v:
Xenotransplantation. 22(6)
Background Intraportal infusion is currently the method of choice for clinical islet cell transplantation but suffers from poor efficacy. As the liver may not represent an optimal transplantation site for Langerhans islets, we examined the potential