Zobrazeno 1 - 10
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pro vyhledávání: '"Leland L. Smith"'
Autor:
Leland L. Smith
Publikováno v:
Free Radical Biology and Medicine. 37:318-324
The recent account of the oxidation of tissue cholesterol by ozone created in human arterial plaques by the oxidation of water by electronically excited (singlet) dioxygen depends on the identification of the oxysterols formed and on the presumption
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b107893871b912bc4dcefaec44489b04
https://doi.org/10.1016/j.freeradbiomed.2004.04.024
https://doi.org/10.1016/j.freeradbiomed.2004.04.024
Autor:
Leland L. Smith
Most components of the biosphere are continuously ex posed to oxygen from the atmosphere. Accordingly, the inex orable deterioration of all organic compounds by the slow attack of oxygen must occur. Despite this eventuality, a definitive treatmen
Autor:
Leland L. Smith
Publikováno v:
Journal of Liquid Chromatography. 16:1731-1747
High performance liquid chromatography of oxysterols of current biochemical and biomedical interest is reviewed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ca00f6f07e59dbf259cb3b5fe77e5f7
https://doi.org/10.1080/10826079308021684
https://doi.org/10.1080/10826079308021684
Autor:
Leland L. Smith, Edward L. Ezell
Publikováno v:
Journal of Natural Products. 54:1645-1650
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96b573248fdd268393322f2db7f2df76
https://doi.org/10.1021/np50078a025
https://doi.org/10.1021/np50078a025
Autor:
Edward L. Ezell, Leland L. Smith
Publikováno v:
Magnetic Resonance in Chemistry. 28:414-418
Fluorine NMR spectra of 23 9α-fluorocorticosteroid analogs established that the 9α-fluorine is subject to deshielding effects by remote structural features (A-ring olefinic unsaturation, A-ring 1α- and 2β-hydroxy and acetoxy features and D-ring 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfdbe858afddeb24cc9beeec213b6171
https://doi.org/10.1002/mrc.1260280506
https://doi.org/10.1002/mrc.1260280506
Autor:
Leland L. Smith, Jon I. Teng
Publikováno v:
Steroids. 61(11)
Cholesterol is oxidized by commercially available Pseudomonas fluorescens cholesterol oxidase to 6 beta-hydroperoxycholest-4-en-3-one as the initial product, with none of the expected produce, cholest-4-en-3-one, formed. The transformation indicates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d756cd6c8125dde233da5cffbfd07a
https://pubmed.ncbi.nlm.nih.gov/8916355
https://pubmed.ncbi.nlm.nih.gov/8916355
Publikováno v:
Steroids. 61(7)
The structures of cholesterol 3 beta-acyl ester ozonides formed by reaction with ozone in participating alcoholic solvents are established by proton and carbon-13 spectra as a 3 beta-acyloxy-7 alpha-alkoxy-(5R,7R)-5 alpha-B-homo-6-oxacholestane-5-hyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f9fb1e552105f03ab513d266b30cbe
https://pubmed.ncbi.nlm.nih.gov/8837291
https://pubmed.ncbi.nlm.nih.gov/8837291
Autor:
Leland L. Smith
Publikováno v:
Lipids. 31(5)
Material dealing with the chemistry, biochemistry, and biological activities of oxysterols is reviewed for the period 1987-1995. Particular attention is paid to the presence of oxysterols in tissues and foods and to their physiological relevance.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fcc6f34faa89b5fa8c93a2601fa3bba
https://pubmed.ncbi.nlm.nih.gov/8727640
https://pubmed.ncbi.nlm.nih.gov/8727640
Autor:
Jon I. Teng, Leland L. Smith
Publikováno v:
Journal of chromatography. A. 691(1-2)
Following oxidation by cholesterol oxidase human erythrocyte oxysterols were analyzed as the corresponding hydroxy-delta 4-3-ketones by HPLC with effluent monitoring at 235 nm. Variable amounts of epimeric cholest-5-ene-3 beta,7-diols, 3 beta-hydroxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee32da1942a707253df034c9ffca275
https://pubmed.ncbi.nlm.nih.gov/7894650
https://pubmed.ncbi.nlm.nih.gov/7894650
Autor:
Leland L. Smith, Ghulam Ansari
Publisher Summary The autoxidation of cholesterol (cholest-5-en-3β-ol) by molecular oxygen ( 3 O 2 ) leads to the formation of a large number of oxysterols of diverse chemistry, biological activities, and biomedical implications. Product analysis by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4aec1a02824ba867e92aefc7ffa371c5
https://doi.org/10.1016/s0076-6879(94)33038-7
https://doi.org/10.1016/s0076-6879(94)33038-7