Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Leland H, Johnston"'
Autor:
J.-L. Moreau, Colin R. Goding, Leland H. Johnston, Anthony L. Johnson, Melanie Lee, S. O'regan
Saccharomyces cerevisiae strains lacking a functional Pho85 cyclin-dependent kinase (cdk) exhibit a complex phenotype, including deregulation of phosphatase genes controlled by the transcription factor Pho4, slow growth on rich media, failure to grow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b654d4c0b15d1240d12fb7342687eeb7
https://doi.org/10.1046/j.1365-2958.2000.02140.x
https://doi.org/10.1046/j.1365-2958.2000.02140.x
Publikováno v:
Cell Cycle. 3:815-820
The mitotic exit network (MEN) is a signal transduction cascade that controls exit from mitosis in budding yeast by triggering the nucleolar release and hence activation of the Cdc14 phosphatase. Activation of the MEN is tightly coordinated with spin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18aff4259e6d8311c0e4f489caf6e0bc
https://doi.org/10.4161/cc.3.6.950
https://doi.org/10.4161/cc.3.6.950
Autor:
Ad Spanos, Marco Geymonat, Katrin Rittinger, Leland H. Johnston, Steven G. Sedgwick, Susan J. M. Smith, Edward Wheatley
Publikováno v:
Journal of Biological Chemistry. 277:28439-28445
The elimination of mitotic kinase activity at the end of mitosis is essential for progression to the next stage of the eukaryotic cell cycle. In budding yeast, this process is controlled by a regulatory cascade called the mitotic exit network. Extens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e4d539e9e8c8c126bc7e51ee107c6b8
https://doi.org/10.1074/jbc.m202540200
https://doi.org/10.1074/jbc.m202540200
Publikováno v:
Molecular Genetics and Genomics. 266:374-384
In Saccharomyces cerevisiae commitment to cell division occurs at a point in G1 termed Start. This important transition is regulated by the cyclin-dependent kinase Cdc28, in association with the G1 cyclins Cln1, 2 and 3. Transcription of the G1 cycli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::901dc906056bd40e75200a24198e6eee
https://doi.org/10.1007/s004380100515
https://doi.org/10.1007/s004380100515
Publikováno v:
Current Biology. 11(10):784-788
The Dbf2 protein kinase functions as part of the mitotic-exit network (MEN), which controls the inactivation of the Cdc28-Clb2 kinase in late mitosis [1]. The MEN includes the Tem1 GTP binding protein; the kinases Cdc15 and Cdc5; Mob1, a protein of u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df598a11b4e95ee9bef9619b0245c3bc
Publikováno v:
Molecular Microbiology. 40:422-432
The yeast transcription factors Ace2p and Swi5p regulate the expression of several target genes involved in mating type switching, exit from mitosis and cell wall function. We describe the analysis of 12 novel targets, some regulated by Ace2p or Swi5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25883ae7aca54fc0c4fe854e0ded7eef
https://doi.org/10.1046/j.1365-2958.2001.02388.x
https://doi.org/10.1046/j.1365-2958.2001.02388.x
Autor:
Kunio Kitada, Makoto Kihara, Satoshi Asano, Akiko Suzuki, Akio Sugino, Yasuo Kawasaki, Leland H. Johnston, Wataru Nakai
Publikováno v:
Journal of Biological Chemistry. 275:35051-35062
The yeast Saccharomyces cerevisiaeCdc7p/Dbf4p protein kinase complex was purified to near homogeneity from insect cells. The complex efficiently phosphorylated yeast Mcm2p and less efficiently the remaining Mcm proteins or other replication proteins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55b0933b1490d0a02f1a34ed4b69cf79
https://doi.org/10.1074/jbc.m003491200
https://doi.org/10.1074/jbc.m003491200
Publikováno v:
Molecular Biology of the Cell. 10:3389-3400
We previously isolated the SKN7 gene in a screen designed to isolate new components of the G1-S cell cycle transcription machinery in budding yeast. We have now found that Skn7 associates with Mbp1, the DNA-binding component of the G1-S transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a22d0ab03dc9d5377aa367785e0001c6
https://doi.org/10.1091/mbc.10.10.3389
https://doi.org/10.1091/mbc.10.10.3389
Publikováno v:
Trends in Cell Biology. 9:249-252
In budding yeast, Dbf4p and Cdc7p control initiation of DNA synthesis. They form a protein kinase - Cdc7p being the catalytic subunit and Dbf4p a cyclin-like molecule that activates the kinase in late G1 phase. Dbf4p also targets Cdc7p to origins of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::841923a57bae4b52204015f2b9f674c9
https://doi.org/10.1016/s0962-8924(99)01586-x
https://doi.org/10.1016/s0962-8924(99)01586-x
Autor:
Kate M. Kramer, Didier Fesquet, Jeremy H. Toyn, Patrick J. Fitzpatrick, Leland H. Johnston, Anthony L. Johnson
Publikováno v:
The EMBO Journal. 18:2424-2434
Exit from mitosis in all eukaroytes requires inactivation of the mitotic kinase. This occurs principally by ubiquitin-mediated proteolysis of the cyclin subunit controlled by the anaphase-promoting complex (APC). However, an abnormal spindle and/or u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fefa3daa64865b162a718bd31f89139e
https://doi.org/10.1093/emboj/18.9.2424
https://doi.org/10.1093/emboj/18.9.2424