Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Lel WHITBREAD"'
Autor:
Anna Hart, Laurent Brassart, Peter Papathanasiou, Paul Blake, Jill Kieffer, Richard Pembrey, Lel Whitbread
Publikováno v:
Drug discovery today. 21(11)
Openness and transparency are important considerations for medicines regulators, where public health is of paramount concern. As part of their commitment to transparency, the European Medicines Agency (EMA) and Therapeutic Goods Administration (TGA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6548d4cd30ce871d1d5a39b1418cb0e0
https://pubmed.ncbi.nlm.nih.gov/27373773
https://pubmed.ncbi.nlm.nih.gov/27373773
Publikováno v:
Biochemical Journal. 334:617-623
The structure and organization of the human Theta-class glutathione S-transferase (GST) genes have been determined. GSTT1 and GSTT2 are separated by approx. 50 kb. They have a similar structure, being composed of five exons with identical exon/intron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0013fae43e04da7722033f1d499799c
https://doi.org/10.1042/bj3340617
https://doi.org/10.1042/bj3340617
Autor:
Runa NJÅLSSON, Katarina CARLSSON, Birgit OLIN, Birgit CARLSSON, Lel WHITBREAD, Galina POLEKHINA, Michael W. PARKER, Svante NORGREN, Bengt MANNERVIK, Philip G. BOARD, Agne LARSSON
Patients with hereditary glutathione synthetase (GS) (EC 6.3.2.3) deficiency present with variable clinical pictures, presumably related to the nature of the mutations involved. In order to elucidate the relationship between genotype, enzyme function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa72155ab06b1b64524f4f2caf0a3bd
https://europepmc.org/articles/PMC1221148/
https://europepmc.org/articles/PMC1221148/
