Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Lekha Dinesh Kumar"'
Autor:
Vinod Kumar Verma, Syed Sultan Beevi, Rekha A. Nair, Aviral Kumar, Ravi Kiran, Liza Esther Alexander, Lekha Dinesh Kumar
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Invasive ductal carcinoma (IDC) is the most common form of breast cancer which accounts for 85% of all breast cancer diagnoses. Non-invasive and early stages have a better prognosis than late-stage invasive cancer that has spread
Externí odkaz:
https://doaj.org/article/0eb673c89bc74959b3aed8823b235873
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract With an average incidence of 1 in every 18,000 live births, retinoblastoma is a rare type of intraocular tumour found to affect patients during their early childhood. It is curable if diagnosed at earlier stages but can become life-threateni
Externí odkaz:
https://doaj.org/article/f3ae57043b034b88a465436b4ee454ef
Publikováno v:
Frontiers in Nanotechnology, Vol 4 (2022)
Over the past two decades, unique and comprehensive cancer treatment has ushered new hope in the holistic management of the disease. Cancer immunotherapy, which harnesses the immune system of the patient to attack the cancer cells in a targeted manne
Externí odkaz:
https://doaj.org/article/e909f1c77b2f4c6b858847ba15a6943b
Autor:
Archana Katoch, Debasis Nayak, Mir Mohd. Faheem, Aviral Kumar, Promod Kumar Sahu, Ajai Prakash Gupta, Lekha Dinesh Kumar, Anindya Goswami
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-13 (2021)
Abstract Epithelial–mesenchymal transition (EMT) is critical for the metastatic dissemination of cancer cells and contributes to drug resistance. In this study, we observed that epithelial colorectal cancer (CRC) cells transiently exposed to 5-fluo
Externí odkaz:
https://doaj.org/article/b0accae5bb8047c8b599a2ba57f662e4
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 25, Iss 5, Pp 979-1010 (2020)
Epithelial to Mesenchymal Transition (EMT) is a biological process characterized by the transition from immotile epithelial cells to motile mesenchymal cells. Though shown to be implicated in many biological processes, it has also been identified to
Externí odkaz:
https://doaj.org/article/af5e301588434a77a3e47e6f61bde53e
Autor:
Guruprasadh Swaminathan, Aisha Shigna, Aviral Kumar, Vishnu Vardhan Byroju, Varsha Reddy Durgempudi, Lekha Dinesh Kumar
Publikováno v:
Frontiers in Nanotechnology, Vol 3 (2021)
Cancer is a significant health hazard of the 21st century, and GLOBOCAN predicts increasing cancer incidence in the coming decades. Though several conventional treatment modalities exist, most of them end up causing off-target and debilitating effect
Externí odkaz:
https://doaj.org/article/b3a632f4cc7f4a88b2cf5204a5feaae4
Autor:
Rekha A Nair, Vinod Kumar Verma, Syed Sultan Beevi, Abdul Rawoof, Liza Esther Alexander, E. Ramanjaneya Prasad, P. Kusuma Kumari, Prashant Kumar, Lekha Dinesh Kumar
Publikováno v:
Translational Oncology, Vol 13, Iss 9, Pp 100800- (2020)
OncomiRs are microRNAs that are associated with early onset of specific cancers. To identify microRNAs involved in pediatric acute lymphoblastic leukemia (ALL) subtypes T-ALL and B-ALL, peripheral blood and bone marrow samples were independently subj
Externí odkaz:
https://doaj.org/article/a6dbe9f23b3f4445a5533c35dcc906f1
Autor:
Lekha Dinesh Kumar, Alan R. Clarke, K. Swaminathan Iyer, Igor Luzinov, Anne Bourdoncle, Bogdan Zdyrko, Nicole M. Smith, Jedy Jose, Anant B. Patel, Liza E. Alexander, Rekha A. Nair, Meera Raja, Ganesh Mahidhara, Trevor Hay, Syed S. Beevi, Tristan D. Clemons, Vinod K. Verma, Naveen K. Tangudu
Supplementary Figure S3: Toxicity studies of the nanoparticle in different organs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fa07d4cec77a62ae610653b9cf4b4a8
https://doi.org/10.1158/1535-7163.22502584
https://doi.org/10.1158/1535-7163.22502584
Autor:
Lekha Dinesh Kumar, Alan R. Clarke, K. Swaminathan Iyer, Igor Luzinov, Anne Bourdoncle, Bogdan Zdyrko, Nicole M. Smith, Jedy Jose, Anant B. Patel, Liza E. Alexander, Rekha A. Nair, Meera Raja, Ganesh Mahidhara, Trevor Hay, Syed S. Beevi, Tristan D. Clemons, Vinod K. Verma, Naveen K. Tangudu
Supplementary Figure S2: Cytotoxicity assays on different cell lines. In vitro cytotoxicity assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d85e7ac04fd421daabae1fa5784d262
https://doi.org/10.1158/1535-7163.22502587.v1
https://doi.org/10.1158/1535-7163.22502587.v1
Autor:
Lekha Dinesh Kumar, Alan R. Clarke, K. Swaminathan Iyer, Igor Luzinov, Anne Bourdoncle, Bogdan Zdyrko, Nicole M. Smith, Jedy Jose, Anant B. Patel, Liza E. Alexander, Rekha A. Nair, Meera Raja, Ganesh Mahidhara, Trevor Hay, Syed S. Beevi, Tristan D. Clemons, Vinod K. Verma, Naveen K. Tangudu
In this article, we report the development and preclinical validation of combinatorial therapy for treatment of cancers using RNA interference (RNAi). RNAi technology is an attractive approach to silence genes responsible for disease onset and progre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::254db200d7bf5335aaa6da40ed522e85
https://doi.org/10.1158/1535-7163.c.6537127.v1
https://doi.org/10.1158/1535-7163.c.6537127.v1