Zobrazeno 1 - 10
of 225
pro vyhledávání: '"Lek Dysoley"'
Autor:
Lek Dysoley, James J. Callery, Voeurng Bunreth, Moul Vanna, Chan Davoeung, Yok Sovann, Sles You, Sam Ol, Rupam Tripura, Rusheng Chew, Arjun Chandna, Céline Christiansen-Jucht, Jayme Hughes, Nguon Sokomar, Top Sophornarann, Jeanne Rideout, Tat Veyvath, Oum Sarith, Thaung Puthy, Hay Sothearoth, Sen Sam An, Sazid Ibna Zaman, Lorenz von Seidlein, Lim Vanthy, Preap Sodavuth, Chrun Vannak, Arjen M. Dondorp, Yoel Lubell, Richard J. Maude, Thomas J. Peto, Bipin Adhikari
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-10 (2024)
Abstract In Southeast Asia malaria elimination is targeted by 2030. Cambodia aims to achieve this by 2025, driven in large part by the urgent need to control the spread of artemisinin-resistant falciparum malaria infections. Rapid elimination depends
Externí odkaz:
https://doaj.org/article/41ade5fce8b5462da2c38af623dfedd8
Autor:
Yoel Lubell, Marco Liverani, Rusheng Chew, Nicholas P J Day, Naomi Waithira, Sue Lee, Akramul Islam, Shayla Islam, Elizabeth M Batty, Richard James Maude, Rupam Tripura, Thomas Julian Peto, Meiwen Zhang, Lek Dysoley, Nan Shwe Nwe Htun, Carlo Perrone, Aninda Sen, Amit Kumer Neogi, Watcharintorn Thongpiam, Jantana Wongsantichon, Chonticha Menggred, Sazid Ibna Zaman, Stuart Blacksell
Publikováno v:
BMJ Open, Vol 14, Iss 3 (2024)
Introduction In low-income and middle-income countries in Southeast Asia, the burden of diseases among rural population remains poorly understood, posing a challenge for effective healthcare prioritisation and resource allocation. Addressing this kno
Externí odkaz:
https://doaj.org/article/6dce235f31434f0990cbbe16399e34bd
Autor:
Arjen M Dondorp, Bipin Adhikari, Lorenz von Seidlein, Rupam Tripura, Thomas J Peto, Makhily Bayo, James J Callery, Lek Dysoley, Salum Mshamu, Samwel Gesase
Publikováno v:
BMJ Global Health, Vol 8, Iss 12 (2023)
The reduction of deaths from malaria in sub-Saharan Africa (SSA) is stalling, whereas many countries in Southeast Asia are approaching malaria elimination. We reviewed the role of community health worker (CHW) programmes in malaria control and elimin
Externí odkaz:
https://doaj.org/article/fec37d60b8b1409ca20e23b9e55097be
Autor:
Mom Ean, Rupam Tripura, Phann Sothea, Uch Savoeun, Thomas J. Peto, Sam Bunthynn, James J. Callery, Ung Soviet, Lek Dysoley, Phaik Yeong Cheah, Bipin Adhikari
Publikováno v:
Global Bioethics, Vol 35, Iss 1 (2024)
Engaging young people in health research has been promoted globally. We explored the outcomes of youth advisory group on health and research engagement (YAGHRE) in rural Cambodia. In May 2021, the Mahidol Oxford Tropical Medicine Research Unit (MORU)
Externí odkaz:
https://doaj.org/article/a00f009784b64863b073d995e662f878
Autor:
Bipin Adhikari, Rupam Tripura, Lek Dysoley, James J. Callery, Thomas J. Peto, Chhoeun Heng, Thy Vanda, Ou Simvieng, Sarah Cassidy-Seyoum, Benedikt Ley, Kamala Thriemer, Arjen M. Dondorp, Lorenz von Seidlein
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-15 (2022)
Abstract Background Quantitative measurement of Glucose-6-Phosphate Dehydrogenase (G6PD) enzyme activity is critical to decide on appropriate treatment and provision of radical cure regimens for vivax malaria. Biosensors are point-of-care semi-quanti
Externí odkaz:
https://doaj.org/article/c4c07f64f9f54c07839aad780879d22a
Autor:
Bipin Adhikari, Rupam Tripura, Thomas J. Peto, James J. Callery, Lorenz von Seidlein, Lek Dysoley, Arjen M. Dondorp
Publikováno v:
The Lancet Regional Health - Southeast Asia, Vol 9, Iss , Pp 100128- (2023)
Summary: In Cambodia, malaria cases are on a trajectory towards the goal of malaria elimination by 2025. Vivax malaria is difficult to eliminate because of hypnozoites that can cause relapse. Primaquine, an 8-aminoquinoline, clears hypnozoites but re
Externí odkaz:
https://doaj.org/article/f44f88f92c664d398e2dbfa827f6342f
Autor:
Walter Robert Taylor, Richard M. Hoglund, Pimnara Peerawaranun, Thuy Nhien Nguyen, Tran Tinh Hien, Arnaud Tarantola, Lorenz von Seidlein, Rupam Tripura, Thomas J. Peto, Arjen M. Dondorp, Jordi Landier, Francois H.Nosten, Frank Smithuis, Koukeo Phommasone, Mayfong Mayxay, Soy Ty Kheang, Chy Say, Kak Neeraj, Leang Rithea, Lek Dysoley, Sim Kheng, Sinoun Muth, Arantxa Roca-Feltrer, Mark Debackere, Rick M. Fairhurst, Ngak Song, Philippe Buchy, Didier Menard, Nicholas J. White, Joel Tarning, Mavuto Mukaka
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-10 (2021)
Abstract Background In many endemic areas, Plasmodium vivax malaria is predominantly a disease of young adults and children. International recommendations for radical cure recommend fixed target doses of 0.25 or 0.5 mg/kg/day of primaquine for 14 day
Externí odkaz:
https://doaj.org/article/99fc57599ac04492ad2d3235bd20aa6f
Autor:
Bipin Adhikari, Rupam Tripura, Lek Dysoley, Thomas J. Peto, James J. Callery, Chhoeun Heng, Thy Vanda, Ou Simvieng, Sarah Cassidy-Seyoum, Kamala Thriemer, Arjen M. Dondorp, Benedikt Ley, Lorenz von Seidlein
Publikováno v:
Pathogens, Vol 12, Iss 3, p 400 (2023)
Vivax malaria can relapse after an initial infection due to dormant liver stages of the parasite. Radical cure can prevent relapses but requires the measurement of glucose-6-phosphate dehydrogenase enzyme (G6PD) activity to identify G6PD-deficient pa
Externí odkaz:
https://doaj.org/article/557d96607063481e808e5d9de18dd74d
Autor:
Varunika Sonani Hapuwatte Ruwanpura, Spike Nowak, Emily Gerth‐Guyette, Minerva Theodora, Lek Dysoley, Mebratom Haile, Koen Peeters Grietens, Ric Norman Price, Caroline Anita Lynch, Kamala Thriemer
Publikováno v:
Asia & the Pacific Policy Studies, Vol 8, Iss 2, Pp 208-242 (2021)
Abstract New diagnostics and treatment options for the radical cure of Plasmodium vivax malaria are now available. At the 2019 annual meeting of the Vivax Working Group of the Asia Pacific Malaria Elimination Network, participants took part in a roun
Externí odkaz:
https://doaj.org/article/5e66da17cf1649bc87db772a75e92ef5
Autor:
Suttipat Srisutham, Wanassanan Madmanee, Jindarat Kouhathong, Kreepol Sutawong, Rupam Tripura, Thomas J Peto, Rob W van der Pluijm, James J Callery, Lek Dysoley, Mayfong Mayxay, Paul N Newton, Tiengkham Pongvongsa, Bouasy Hongvanthong, Nicholas P J Day, Nicholas J White, Arjen M Dondorp, Mallika Imwong
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0278928 (2022)
BackgroundThe amplification of GTP cyclohydrolase 1 (pfgch1) in Plasmodium falciparum has been linked to the upregulation of the pfdhfr and pfdhps genes associated with resistance to the antimalarial drug sulfadoxine-pyrimethamine. During the 1990s a
Externí odkaz:
https://doaj.org/article/508a1dd6505c4cc7b9f6b0c7da410a60