Zobrazeno 1 - 10 of 74 pro vyhledávání: '"Leite, REP"'
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Loss of lamin-B1 and defective nuclear morphology are hallmarks of astrocyte senescence in vitro and in the aging human hippocampus
Autor: Leite Rep, Vargas G, Ricardo Nitrini, Jinte Middeldorp, Neves LdS, Damico, Claudia K. Suemoto, Gomes Fca, Wilson Jacob-Filho, Lea T. Grinberg, Matias I, Elly M. Hol, Araujo Apb, Diniz Lp
The increase in senescent cells in tissues, including the brain, is a general feature of normal aging and age-related pathologies. Senescent cells exhibit a specific phenotype, which includes an altered nuclear morphology and transcriptomic changes.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c3d385ae22a2df0aa3d8310cf0d00776
https://doi.org/10.1101/2021.04.27.440997
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3
Prevalence of transactive response DNA-binding protein 43 (TDP-43) proteinopathy in cognitively normal older adults: systematic review and meta-analysis
Autor: Nascimento, C, Di Lorenzo Alho, AT, Bazan Conceição Amaral, C, Leite, REP, Nitrini, R, Jacob-Filho, W, Pasqualucci, CA, Hokkanen, SRK, Hunter, S, Keage, H, Kovacs, GG, Grinberg, LT, Suemoto, CK
Publikováno v: Neuropathology and applied neurobiology, vol 44, iss 3
ObjectiveTo perform a systematic review and meta-analysis on the prevalence of transactive response DNA-binding protein 43 (TDP-43) proteinopathy in cognitively normal older adults.MethodsWe systematically reviewed and performed a meta-analysis on th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::60199bc91abe5b88334e18da8ef78e2b
https://escholarship.org/uc/item/4fk7k0x5
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4
d Argyrophilic Grain Disease: Demographics, Clinical, and Neuropathological Features From a Large Autopsy Study
Autor: Rodriguez, RD, Suemoto, CK, Molina, M, Nascimento, CF, Leite, REP, de Lucena Ferretti-Rebustini, RE, Farfel, JM, Heinsen, H, Nitrini, R, Ueda, K, Pasqualucci, CA, Jacob-Filho, W, Yaffe, K, Grinberg, LT
Publikováno v: Rodriguez, RD; Suemoto, CK; Molina, M; Nascimento, CF; Leite, REP; de Lucena Ferretti-Rebustini, RE; et al.(2016). d Argyrophilic Grain Disease: Demographics, Clinical, and Neuropathological Features From a Large Autopsy Study. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 75(7), 628-635. doi: 10.1093/jnen/nlw034. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/010967bn
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::d27ca881546dfd7c75a1675d06beb2ec
http://www.escholarship.org/uc/item/010967bn
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5
Combined enrichment of neuromelanin granules and synaptosomes from human substantia nigra pars compacta tissue for proteomic analysis
Autor: Plum, S, Helling, S, Theiss, C, Leite, REP, May, C, Jacob-Filho, W, Eisenacher, M, Kuhlmann, K, Meyer, HE, Riederer, P, Grinberg, LT, Gerlach, M, Marcus, K
This article gives a detailed description of a protocol using density gradient centrifugation for the enrichment of neuromelanin granules and synaptosomes from low amounts (≥0.15g) of human substantia nigra pars compacta tissue. This has a great ad
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::3d33dee2b7549f883c676b447ec189dd
https://escholarship.org/uc/item/18w1x6z0
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6
Prevalence of transactive response DNA-binding protein 43 (TDP-43) proteinopathy in cognitively normal older adults: systematic review and meta-analysis
Autor: Gabor G. Kovacs, A. T. Di Lorenzo Alho, Wilson Jacob-Filho, Renata Elaine Paraizo Leite, Hannah A.D. Keage, Ricardo Nitrini, C. Bazan Conceição Amaral, Lea T. Grinberg, C. A. Pasqualucci, Camila F. Nascimento, Claudia K. Suemoto, Sally Hunter, Suvi R.K. Hokkanen
Publikováno v: Neuropathology and Applied Neurobiology. 44:286-297
Objective: To perform a systematic review and meta-analysis on the prevalence of transactive response DNA-binding protein 43 (TDP-43) proteinopathy in cognitively normal older adults. Methods: We systematically reviewed and performed a meta-analysis
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeff05cbf860497a2f2edeebd53776fa
https://doi.org/10.1111/nan.12430
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7
Akademický článek
Comprehensive mapping of synaptic vesicle protein 2A (SV2A) in health and neurodegenerative diseases: a comparative analysis with synaptophysin and ground truth for PET-imaging interpretation.
Autor: Shanaki Bavarsad M; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco (UCSF), 675 Nelson Rising Lane, Suite 190, San Francisco, CA, 94158, USA., Spina S; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco (UCSF), 675 Nelson Rising Lane, Suite 190, San Francisco, CA, 94158, USA., Oehler A; Institute for Neurodegenerative Diseases, University of California, San Francisco (UCSF), San Francisco, USA., Allen IE; Department of Biostatistics and Epidemiology, University of California, San Francisco (UCSF), San Francisco, USA., Suemoto CK; Discipline of Geriatrics, University of Sao Paulo Medical School, Sao Paulo, Brazil., Leite REP; Department of Pathology, Lim22, University of Sao Paulo Medical School, Sao Paulo, Brazil., Seeley WS; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco (UCSF), 675 Nelson Rising Lane, Suite 190, San Francisco, CA, 94158, USA., Green A; Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco (UCSF), San Francisco, USA., Jagust W; Department of Neuroscience, University of California Berkeley, Berkeley, USA., Rabinovici GD; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco (UCSF), 675 Nelson Rising Lane, Suite 190, San Francisco, CA, 94158, USA., Grinberg LT; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco (UCSF), 675 Nelson Rising Lane, Suite 190, San Francisco, CA, 94158, USA. lea.grinberg@ucsf.edu.; Department of Pathology, Lim22, University of Sao Paulo Medical School, Sao Paulo, Brazil. lea.grinberg@ucsf.edu.
Publikováno v: Acta neuropathologica [Acta Neuropathol] 2024 Oct 30; Vol. 148 (1), pp. 58. Date of Electronic Publication: 2024 Oct 30.
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8
Akademický článek
Defective regulation of the eIF2-eIF2B translational axis underlies depressive-like behavior in mice and correlates with major depressive disorder in humans.
Autor: Isaac AR; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.; Multidisciplinary Research Core in Biology (NUMPEX-BIO), Campus Duque de Caxias Professor Geraldo Cidade, Federal University of Rio de Janeiro, Duque de Caxias, RJ, Brazil., Chauvet MG; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Lima-Filho R; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Wagner BA; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Caroli BG; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Leite REP; Department of Pathology, University of São Paulo Medical School, São Paulo, SP, Brazil., Suemoto CK; Division of Geriatrics, University of São Paulo Medical School, São Paulo, SP, Brazil., Nunes PV; Department of Psychiatry, University of São Paulo Medical School, São Paulo, SP, Brazil., De Felice FG; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.; Centre for Neuroscience Studies, Department of Biomedical and Molecular Sciences & Department of Psychiatry, Queen's University, Kingston, ON, Canada.; D'Or Institute for Research and Education, Rio de Janeiro, RJ, Brazil., Ferreira ST; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.; D'Or Institute for Research and Education, Rio de Janeiro, RJ, Brazil.; Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Lourenco MV; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil. mychael@bioqmed.ufrj.br.
Publikováno v: Translational psychiatry [Transl Psychiatry] 2024 Oct 01; Vol. 14 (1), pp. 397. Date of Electronic Publication: 2024 Oct 01.
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9
Akademický článek
Hypertension may associate with cerebral small vessel disease and infarcts through the pathway of intracranial atherosclerosis.
Autor: Takahashi MKN; Division of Geriatrics, University of Sao Paulo Medical School, Sao Paulo 01246-903, Brazil., Paradela RS; Division of Geriatrics, University of Sao Paulo Medical School, Sao Paulo 01246-903, Brazil., Grinberg LT; Department of Pathology, University of São Paulo Medical School, Sao Paulo, SP 01246-903, Brazil; Memory and Aging Center, Weill Institute for Neurosciences, Dept. of Neurology, University of California San Francisco, CA 94158, USA., Leite REP; Department of Pathology, University of São Paulo Medical School, Sao Paulo, SP 01246-903, Brazil., Farias-Itao DS; Department of Pathology, University of São Paulo Medical School, Sao Paulo, SP 01246-903, Brazil., Paes VR; Department of Pathology, University of São Paulo Medical School, Sao Paulo, SP 01246-903, Brazil., Braga ME; Division of Geriatrics, University of Sao Paulo Medical School, Sao Paulo 01246-903, Brazil., Naslavsky MS; Human Genome and Stem Cell Center, Biosciences Institute, University of Sao Paulo, Sao Paulo 05508-090, Brazil., Zatz M; Human Genome and Stem Cell Center, Biosciences Institute, University of Sao Paulo, Sao Paulo 05508-090, Brazil., Jacob-Filho W; Division of Geriatrics, University of Sao Paulo Medical School, Sao Paulo 01246-903, Brazil., Nitrini R; Department of Neurology, University of Sao Paulo Medical School, SP 01246-903, Brazil., Pasqualucci CA; Department of Pathology, University of São Paulo Medical School, Sao Paulo, SP 01246-903, Brazil., Suemoto CK; Division of Geriatrics, University of Sao Paulo Medical School, Sao Paulo 01246-903, Brazil. Electronic address: cksuemoto@usp.br.
Publikováno v: Neurobiology of aging [Neurobiol Aging] 2025 Jan; Vol. 145, pp. 84-95. Date of Electronic Publication: 2024 Nov 07.
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10
Akademický článek
Causes of death in individuals with lifetime major depression: a comprehensive machine learning analysis from a community-based autopsy center.
Autor: Nunes PV; Faculdade de Medicina de Jundiai, rua Francisco Telles, 250, Jundiai, SP, 13202-550, Brazil. paula@formato.com.br.; Faculdade de Medicina, Universidade de Sao Paulo, Av. Dr. Arnaldo, 455, Sao Paulo, SP, 01246-903, Brazil. paula@formato.com.br., Mancine L; Instituto de Informatica Universidade Federal de Goias, Alameda Palmeiras, s/n, Goiania, GO, 74690-900, Brazil.; Instituto Federal Goiano, Campus Ceres, GO-154, km 218, zip, Ceres, GO, 76300-000, Brazil., Neves BA; Faculdade de Medicina de Jundiai, rua Francisco Telles, 250, Jundiai, SP, 13202-550, Brazil., Leite REP; Faculdade de Medicina, Universidade de Sao Paulo, Av. Dr. Arnaldo, 455, Sao Paulo, SP, 01246-903, Brazil., Nascimento C; Federal University of Sao Paulo, rua Pedro de Toledo, 669, Sao Paulo, SP, 04039-032, Brazil., Pasqualucci CA; Faculdade de Medicina, Universidade de Sao Paulo, Av. Dr. Arnaldo, 455, Sao Paulo, SP, 01246-903, Brazil., Lafer B; Faculdade de Medicina, Universidade de Sao Paulo, Av. Dr. Arnaldo, 455, Sao Paulo, SP, 01246-903, Brazil., Salvini R; Instituto de Informatica Universidade Federal de Goias, Alameda Palmeiras, s/n, Goiania, GO, 74690-900, Brazil., Suemoto CK; Faculdade de Medicina, Universidade de Sao Paulo, Av. Dr. Arnaldo, 455, Sao Paulo, SP, 01246-903, Brazil.
Publikováno v: BMC psychiatry [BMC Psychiatry] 2024 Jul 24; Vol. 24 (1), pp. 531. Date of Electronic Publication: 2024 Jul 24.
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