Synthesis of Carvone Derivatives and In Silico and In Vitro Screening of Anti-Inflammatory Activity in Murine Macrophages.

Autor: Moço G; Faculty of Pharmacy, University of Coimbra, 3004-548 Coimbra, Portugal.; Centre for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504 Coimbra, Portugal., Sousa C; Centre for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Interdisciplinary Research Institute, University of Coimbra, 3030-789 Coimbra, Portugal., Capitão A; Centre for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504 Coimbra, Portugal.; Interdisciplinary Research Institute, University of Coimbra, 3030-789 Coimbra, Portugal., MacKinnon SS; Cyclica Inc., Toronto, ON M5J 1A7, Canada., Leitão AJ; Faculty of Pharmacy, University of Coimbra, 3004-548 Coimbra, Portugal.; Centre for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504 Coimbra, Portugal., Mendes AF; Faculty of Pharmacy, University of Coimbra, 3004-548 Coimbra, Portugal.; Centre for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504 Coimbra, Portugal.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Jan 23; Vol. 24 (3). Date of Electronic Publication: 2023 Jan 23.

Elucidation of the Mechanism Underlying the Anti-Inflammatory Properties of (S)-(+)-Carvone Identifies a Novel Class of Sirtuin-1 Activators in a Murine Macrophage Cell Line.

Autor: Sousa C; Centre for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal.; Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504 Coimbra, Portugal., Neves BM; Department of Medical Sciences and Institute of Biomedicine-iBiMED, University of Aveiro, 3810-193 Aveiro, Portugal., Leitão AJ; Centre for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal.; Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504 Coimbra, Portugal., Mendes AF; Centre for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal.; Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504 Coimbra, Portugal.

Publikováno v: Biomedicines [Biomedicines] 2021 Jul 04; Vol. 9 (7). Date of Electronic Publication: 2021 Jul 04.

In vitro anti-Leishmania activity of T6 synthetic compound encapsulated in yeast-derived β-(1,3)-d-glucan particles.

Autor: Volpato H; Postgraduate Program in Biological Sciences, State University of Maringá (UEM), Maringá, Paraná, Brazil., Scariot DB; Postgraduate Program in Pharmaceutical Sciences, State University of Maringá (UEM), Maringá, Paraná, Brazil., Soares EFP; Faculty of Pharmacy, University of Coimbra (FFUC), Coimbra, Portugal; Center for Neuroscience and Cell Biology (CNC), University of Coimbra, Coimbra, Portugal., Jacomini AP; Postgraduate Program in Chemistry, State University of Maringá (UEM), Maringá, Paraná, Brazil., Rosa FA; Postgraduate Program in Chemistry, State University of Maringá (UEM), Maringá, Paraná, Brazil. Electronic address: farosa@uem.br., Sarragiotto MH; Postgraduate Program in Chemistry, State University of Maringá (UEM), Maringá, Paraná, Brazil. Electronic address: mhsarragiotto@uem.br., Ueda-Nakamura T; Postgraduate Program in Biological Sciences, State University of Maringá (UEM), Maringá, Paraná, Brazil. Electronic address: cvnakamura@uem.br., Rubira AF; Postgraduate Program in Chemistry, State University of Maringá (UEM), Maringá, Paraná, Brazil. Electronic address: afrubira@uem.br., Pereira GM; Postgraduate Program in Chemistry, State University of Maringá (UEM), Maringá, Paraná, Brazil. Electronic address: gmpereira2@uem.br., Manadas R; Faculty of Pharmacy, University of Coimbra (FFUC), Coimbra, Portugal. Electronic address: rmanadas@ff.uc.pt., Leitão AJ; Faculty of Pharmacy, University of Coimbra (FFUC), Coimbra, Portugal; Center for Neuroscience and Cell Biology (CNC), University of Coimbra, Coimbra, Portugal. Electronic address: ajleitao@ff.uc.pt., Borges O; Faculty of Pharmacy, University of Coimbra (FFUC), Coimbra, Portugal; Center for Neuroscience and Cell Biology (CNC), University of Coimbra, Coimbra, Portugal. Electronic address: olga@ci.uc.pt., Nakamura CV; Postgraduate Program in Biological Sciences, State University of Maringá (UEM), Maringá, Paraná, Brazil; Postgraduate Program in Pharmaceutical Sciences, State University of Maringá (UEM), Maringá, Paraná, Brazil. Electronic address: tunakamura@uem.br., Sousa MDC; Faculty of Pharmacy, University of Coimbra (FFUC), Coimbra, Portugal; Center for Neuroscience and Cell Biology (CNC), University of Coimbra, Coimbra, Portugal. Electronic address: mcsousa@ci.uc.pt.

Publikováno v: International journal of biological macromolecules [Int J Biol Macromol] 2018 Nov; Vol. 119, pp. 1264-1275. Date of Electronic Publication: 2018 Aug 07.

Neurosteroids: Can a 2alpha,3alpha-epoxy ring make up for the 3alpha-hydroxyl group?

Autor: Kasal A; Institute of Organic Chemistry and Biochemistry, Academy of Sciences, Prague CZ16610, Czech Republic. Electronic address: Kasal@uochb.cas.cz., Buděšínský M; Institute of Organic Chemistry and Biochemistry, Academy of Sciences, Prague CZ16610, Czech Republic., Mareš P; Institute of Physiology, Academy of Sciences, CZ14220 Prague 4, Czech Republic., Krištofíková Z; Alzheimer's Disease Center, National Institute of Mental Health, Klecany CZ25067, Czech Republic., Leitão AJ; Faculdade de Farmácia, Universidade de Coimbra, 3000-508 Coimbra, Portugal; CNC - Centre for Neurosciences and Cell Biology, University of Coimbra, 3004-517 Coimbra, Portugal., Sá e Melo ML; Faculdade de Farmácia, Universidade de Coimbra, 3000-508 Coimbra, Portugal; CNC - Centre for Neurosciences and Cell Biology, University of Coimbra, 3004-517 Coimbra, Portugal., Silva MM; Faculdade de Farmácia, Universidade de Coimbra, 3000-508 Coimbra, Portugal; CNC - Centre for Neurosciences and Cell Biology, University of Coimbra, 3004-517 Coimbra, Portugal.

Publikováno v: Steroids [Steroids] 2016 Jan; Vol. 105, pp. 12-8. Date of Electronic Publication: 2015 Nov 26.