Zobrazeno 1 - 10
of 789
pro vyhledávání: '"Leishmanicidal activity"'
Autor:
Maria Carolina Silva Marques, Nídia Cristiane Yoshida, Eduardo Caio Torres-Santos, Fernanda Rodrigues Garcez, Walmir Silva Garcez
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionLeishmaniasis, a neglected tropical parasitic disease, is regarded as a major public health problem worldwide. The first-line drugs for leishmaniasis suffer from limitations related to toxicity and the development of resistance in certain
Externí odkaz:
https://doaj.org/article/b75e1efb896c40ca89003bccab506aaa
Autor:
ROSANE D. CEZAR, ADRIANO O. DA SILVA, ROSÂNGELA S. LOPES, CELSO V. NAKAMURA, JEAN HENRIQUE S. RODRIGUES, ESTELA MARIANA G. LOURENÇO, SUMBAL SABA, ADILSON BEATRIZ, JAMAL RAFIQUE, DÊNIS P. DE LIMA
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 96, Iss 2 (2024)
Abstract In pursuit of potential agents to treat Chagas disease and leishmaniasis, we report the design, synthesis, and identification novel naphthoquinone hydrazide-based molecular hybrids. The compounds were subjected to in vitro trypanocide and le
Externí odkaz:
https://doaj.org/article/0adb625c4550495bb17bb55f60332f9f
Autor:
Poliana Queiroz-Souza, Adan Galue-Parra, Lienne Silveira Moraes, Caroline Gomes Macedo, Ana Paula Drummond Rodrigues, Victor H. S. Marinho, Fabricio H. Holanda, Irlon M. Ferreira, Edilene Oliveira da Silva
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Leishmaniasis encompasses a cluster of neglected tropical diseases triggered by kinetoplastid phatogens belonging to the genus Leishmania. Current therapeutic approaches are toxic, expensive, and require long-term treatment. Nanoparticles are emergin
Externí odkaz:
https://doaj.org/article/ad08fbad2f184d3183a72c652f8de604
Autor:
Rym Essid, Sarra Kefi, Bilel Damergi, Ghassen Abid, Nadia Fares, Selim Jallouli, Islem Abid, Dina Hussein, Olfa Tabbene, Ferid Limam
Publikováno v:
Molecules, Vol 29, Iss 8, p 1876 (2024)
The present study aimed to evaluate the leishmanicidal potential of the essential oil (EO) of Micromeria (M.) nervosa and to investigate its molecular mechanism of action by qPCR. Furthermore, in silicointeraction study of the major M. nervosa EO com
Externí odkaz:
https://doaj.org/article/7286615813f54774bb58ff0b15226291
Autor:
Alice P. Borges, Malu M. S. Obata, Silvia H. Libardi, Rafael O. Trevisan, Victor M. Deflon, Ulrich Abram, Francis B. Ferreira, Luiz Antônio S. Costa, Antonio O. T. Patrocínio, Marcos V. da Silva, Júlio C. Borges, Pedro I. S. Maia
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 452 (2024)
Leishmaniasis is a group of parasitic diseases with the potential to infect more than 1 billion people; however, its treatment is still old and inadequate. In order to contribute to changing this view, this work consisted of the development of comple
Externí odkaz:
https://doaj.org/article/ea751c10cb2546d0868d017ad900d1b8
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Abdur Rauf, Saima Naz, Naveed Muhammad, Abdul Wadood, Adnan Khan, Abdulrahman Alsahammari, Metab Alharbi, Philippe Jeandet
Publikováno v:
Journal of King Saud University: Science, Vol 35, Iss 3, Pp 102572- (2023)
Objective: Medicinal plants are the mainstay of various chemical constituents responsible for curing or mitigating different pathological and non-pathological health issues. In this regard, the current research work was subjected to finding the best
Externí odkaz:
https://doaj.org/article/735262a9b6254b05bdee712e4977da56
Autor:
Richard Pereira Dutra, Marcos Marinho de Sousa, Maria Simone Pereira Maciel Mignoni, Karla Gabriela Mota de Oliveira, Euzineti Borges Pereira, Aline Santana Figueredo, Arthur André Castro da Costa, Tatielle Gomes Dias, Cleydlenne Costa Vasconcelos, Lucilene Amorim Silva, Aramys Silva Reis, Alberto Jorge Oliveira Lopes
Publikováno v:
Metabolites, Vol 13, Iss 9, p 1027 (2023)
Leishmaniasis is caused by protozoans of the genus Leishmania, and its treatment is highly toxic, leading to treatment discontinuation and the emergence of resistant strains. In this study, we assessed the leishmanicidal activity and chemical composi
Externí odkaz:
https://doaj.org/article/d66c42ff230c467780f7e73d34308e95
Autor:
Fernanda Giesel Baldissera, Tiago Fazolo, Matheus Brasil da Silva, Paulo Cesar de Santana Filho, Vinícius Demétrio da Silva, David Max Rivillo Perez, Joice Sandra Klitzke, Eduardo Giovanni de Oliveira Soares, Luiz Carlos Rodrigues Júnior, Alessandra Peres, Eliane Dallegrave, Kely Campos Navegantes-Lima, Marta Chagas Monteiro, Henri Stephan Schrekker, Pedro Roosevelt Torres Romão
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
In this study we explored the previously established leishmanicidal activity of a complementary set of 24 imidazolium salts (IS), 1-hexadecylimidazole (C16Im) and 1-hexadecylpyridinium chloride (C16PyrCl) against Leishmania (Leishmania) amazonensis a
Externí odkaz:
https://doaj.org/article/09b41f869b0640bc83f431d369c9ec10
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.