Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Leisheng Shi"'
Autor:
Xianfeng Li, Yan Wang, Qingjie Min, Weimin Zhang, Huajing Teng, Chao Li, Kun Zhang, Leisheng Shi, Bin Wang, Qimin Zhan
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 3841-3853 (2023)
Background: Esophageal cancers are primarily categorized as esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EAC). While various (epi) genomic alterations associated with tumor development in ESCC and EAC have been documented,
Externí odkaz:
https://doaj.org/article/8d96215b03e441d0a1075356647a282d
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 2416-2422 (2021)
Addiction, a disorder of maladaptive brain plasticity, is associated with changes in numerous gene expressions. Nowadays, high-throughput sequencing data on addictive substance-induced gene expression have become widely available. A resource for comp
Externí odkaz:
https://doaj.org/article/d484b8ca8229417e91ddbb89cafdfde1
Autor:
Jibiao Fan, Leisheng Shi, Qi Liu, Zhipeng Zhu, Fan Wang, Runxian Song, Jimeng Su, Degui Zhou, Xiao Chen, Kailong Li, Lixiang Xue, Lichao Sun, Fengbiao Mao
Publikováno v:
Nucleic Acids Research. 51:D1249-D1256
CRISPR-Cas base editing (BE) system is a powerful tool to expand the scope and efficiency of genome editing with single-nucleotide resolution. The editing efficiency, product purity, and off-target effect differ among various BE systems. Herein, we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc06379ea1ba03cc96b492950642b6f3
https://doi.org/10.1093/nar/gkac967
https://doi.org/10.1093/nar/gkac967
Autor:
Lun Li, Bo Xu, Dongmei Tian, Anke Wang, Junwei Zhu, Cuiping Li, Na Li, Wei Zhao, Leisheng Shi, Yongbiao Xue, Zhang Zhang, Yiming Bao, Wenming Zhao, Shuhui Song
Publikováno v:
Briefings in Bioinformatics. 24
Haplotype networks are graphs used to represent evolutionary relationships between a set of taxa and are characterized by intuitiveness in analyzing genealogical relationships of closely related genomes. We here propose a novel algorithm termed McAN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db59717034f76dca1d628b47117eef1c
https://doi.org/10.1093/bib/bbad174
https://doi.org/10.1093/bib/bbad174
Autor:
Fengbiao Mao, Jie Qiao, Shasha Ruan, Lin Chen, Yifan Liu, Leisheng Shi, Yifan Chen, Xiaolu Zhao, Mingkun Li, Wenjian Bi
Publikováno v:
Nucleic Acids Research
Rapid advances in high-throughput sequencing technologies have led to the discovery of thousands of extrachromosomal circular DNAs (eccDNAs) in the human genome. Loss-of-function experiments are difficult to conduct on circular and linear chromosomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c12096d38da9a224356cce7c45516da
http://europepmc.org/articles/PMC8728191
http://europepmc.org/articles/PMC8728191
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 2416-2422 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 2416-2422 (2021)
Graphical abstract AddictGene and its easy-to-use web interface was built by integrating gene expression, gene-gene interaction, gene-drug interaction and epigenetic regulatory annotation of differentially expressed genes associated with abused subst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acaf2601cdac8d4a2044908072574b1c
https://doi.org/10.1016/j.csbj.2021.04.027
https://doi.org/10.1016/j.csbj.2021.04.027
Autor:
Xiaohui Shi, Huajing Teng, Leisheng Shi, Wenjian Bi, Wenqing Wei, Fengbiao Mao, Zhongsheng Sun
Publikováno v:
Briefings in bioinformatics. 23(2)
Optimal methods could effectively improve the accuracy of predicting and identifying candidate driver genes. Various computational methods based on mutational frequency, network and function approaches have been developed to identify mutation driver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b91ea4068eadeaaaf2011c6d22ccf50c
https://pubmed.ncbi.nlm.nih.gov/35037014
https://pubmed.ncbi.nlm.nih.gov/35037014
Autor:
Lu Kang, Mingkun Li, Jian Rao, Yeming Wang, Conghui Wang, Li Zhang, Zijie Shen, Jizhou Li, Haibo Li, Jiaxin Zhong, Ying Wang, Jianbin Wang, Yan Xiao, Bin Cao, Jing Yang, Qiong Li, Xinming Wang, Yanyi Huang, Xia Li, Guohui Fan, Leisheng Shi, Li Guo, Xiaohui Zou, Lin Di, Jianwei Wang, Lili Ren, Jie Li
Publikováno v:
American journal of respiratory and critical care medicine. 204(12)
Rationale: Alteration of human respiratory microbiota had been observed in COVID-19. How the microbiota is associated with the prognosis in COVID-19 is unclear. Objectives: To characterize the feat...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a64d167fb181bb9e756f2e84abe1ebef
https://pubmed.ncbi.nlm.nih.gov/34748719
https://pubmed.ncbi.nlm.nih.gov/34748719
Autor:
Ying Wang, Wen Liu, Leisheng Shi, Haibo Li, Jizhou Li, Guohui Fan, Lu Kang, Xia Li, Jianbin Wang, Yan Xiao, Dingyu Zhang, Lili Ren, Bin Cao, Mingkun Li, Jie Li, Yanyi Huang, Li Guo, Qiong Li, Jian Rao, Yeming Wang, Li Zhang, Xinming Wang, Xiaohui Zhou, Jiaxin Zhong, Lin Di, Zijie Shen, Conghui Wang, Jianwei Wang, Jing Yang
Background: The pandemic of Coronavirus disease 2019 (COVID-19) is ongoing globally, which is a big challenge for public health. Alteration of human microbiota had been observed in COVID-19. However, it is unknown how the microbiota is associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0972fd7e1c23886776e44e597e951889
https://doi.org/10.21203/rs.3.rs-95239/v1
https://doi.org/10.21203/rs.3.rs-95239/v1
Autor:
Lili Ren, Chao Wu, Li Guo, Jiacheng Yao, Conghui Wang, Yan Xiao, Angela Oliveira Pisco, Zhiqiang Wu, Xiaobo Lei, Yiwei Liu, Leisheng Shi, Lianlian Han, Hu Zhang, Xia Xiao, Jingchuan Zhong, Hongping Wu, Mingkun Li, Stephen R. Quake, Yanyi Huang, Jianbin Wang, Jianwei Wang
Bats are a major “viral reservoir” in nature and there is a great interest in not only the cell biology of their innate and adaptive immune systems, but also in the expression patterns of receptors used for cellular entry by viruses with potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::052dcdb1ed5acccce78db9d74b1bda77
https://doi.org/10.1101/2020.06.30.175778
https://doi.org/10.1101/2020.06.30.175778