Zobrazeno 1 - 10 of 28 pro vyhledávání: '"Leiser SC"'
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4
Akademický článek
Evaluation of variation in preclinical electroencephalographic (EEG) spectral power across multiple laboratories and experiments: An EQIPD study.
Autor: Ahuis TP; Groningen Institute for Evolutionary Life Sciences (GELIFES), Neurobiology, University of Groningen, Groningen, The Netherlands.; Department of CNS Diseases Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany., Smyk MK; Groningen Institute for Evolutionary Life Sciences (GELIFES), Neurobiology, University of Groningen, Groningen, The Netherlands.; Department of Neuroscience, Janssen Research & Development, A Division of Janssen Pharmaceutica NV, Beerse, Belgium., Laloux C; Pharmalex, Mont-Saint-Guibert, Belgium., Aulehner K; Institute of Pharmacology, Toxicology, and Pharmacy, Ludwig-Maximilians- Universität (LMU), Munich, Germany., Bray J; Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, Scotland, United Kingdom., Waldron AM; Institute of Pharmacology, Toxicology, and Pharmacy, Ludwig-Maximilians- Universität (LMU), Munich, Germany., Miljanovic N; Institute of Pharmacology, Toxicology, and Pharmacy, Ludwig-Maximilians- Universität (LMU), Munich, Germany., Seiffert I; Institute of Pharmacology, Toxicology, and Pharmacy, Ludwig-Maximilians- Universität (LMU), Munich, Germany., Song D; Translational EEG, PsychoGenics Inc., Paramus, New Jersey, United States of America., Boulanger B; Pharmalex, Mont-Saint-Guibert, Belgium., Jucker M; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Potschka H; Institute of Pharmacology, Toxicology, and Pharmacy, Ludwig-Maximilians- Universität (LMU), Munich, Germany., Platt B; Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, Scotland, United Kingdom., Riedel G; Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, Scotland, United Kingdom., Voehringer P; Department of CNS Diseases Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany., Nicholson JR; Department of CNS Diseases Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany., Drinkenburg WHIM; Groningen Institute for Evolutionary Life Sciences (GELIFES), Neurobiology, University of Groningen, Groningen, The Netherlands.; Department of Neuroscience, Janssen Research & Development, A Division of Janssen Pharmaceutica NV, Beerse, Belgium., Kas MJH; Groningen Institute for Evolutionary Life Sciences (GELIFES), Neurobiology, University of Groningen, Groningen, The Netherlands., Leiser SC; Translational EEG, PsychoGenics Inc., Paramus, New Jersey, United States of America.
Publikováno v: PloS one [PLoS One] 2024 Oct 29; Vol. 19 (10), pp. e0309521. Date of Electronic Publication: 2024 Oct 29 (Print Publication: 2024).
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5
Akademický článek
Inhibition of MEK-ERK signaling reduces seizures in two mouse models of tuberous sclerosis complex.
Autor: Nguyen LH; Department of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA; Department of Cellular & Molecular Physiology, Yale University School of Medicine, New Haven, CT, USA., Leiser SC; Department of Translational EEG, PsychoGenics, Inc., Paramus, NJ, USA., Song D; Department of Translational EEG, PsychoGenics, Inc., Paramus, NJ, USA., Brunner D; Tuberous Sclerosis Alliance, Silver Spring, MD, USA., Roberds SL; Tuberous Sclerosis Alliance, Silver Spring, MD, USA., Wong M; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Bordey A; Department of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA; Department of Cellular & Molecular Physiology, Yale University School of Medicine, New Haven, CT, USA. Electronic address: angelique.bordey@yale.edu.
Publikováno v: Epilepsy research [Epilepsy Res] 2022 Mar; Vol. 181, pp. 106890. Date of Electronic Publication: 2022 Feb 18.
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6
Akademický článek
Novel brain permeant mTORC1/2 inhibitors are as efficacious as rapamycin or everolimus in mouse models of acquired partial epilepsy and tuberous sclerosis complex.
Autor: Theilmann W; Department of Pharmacology, Toxicology, and Pharmacy, University of Veterinary Medicine Hannover, Germany., Gericke B; Department of Pharmacology, Toxicology, and Pharmacy, University of Veterinary Medicine Hannover, Germany; Center for Systems Neuroscience, Hannover, Germany., Schidlitzki A; Department of Pharmacology, Toxicology, and Pharmacy, University of Veterinary Medicine Hannover, Germany., Muneeb Anjum SM; Department of Pharmacology, Toxicology, and Pharmacy, University of Veterinary Medicine Hannover, Germany., Borsdorf S; Department of Pharmacology, Toxicology, and Pharmacy, University of Veterinary Medicine Hannover, Germany., Harries T; Department of Pharmacology, Toxicology, and Pharmacy, University of Veterinary Medicine Hannover, Germany., Roberds SL; Tuberous Sclerosis Alliance, Silver Spring, MD, USA., Aguiar DJ; Tuberous Sclerosis Alliance, Silver Spring, MD, USA., Brunner D; PsychoGenics, Paramus, NJ, USA., Leiser SC; PsychoGenics, Paramus, NJ, USA., Song D; PsychoGenics, Paramus, NJ, USA., Fabbro D; PIQUR Therapeutics AG, Basel, Switzerland., Hillmann P; PIQUR Therapeutics AG, Basel, Switzerland., Wymann MP; Department of Biomedicine, University of Basel, Mattenstrasse 28, 4058, Basel, Switzerland., Löscher W; Department of Pharmacology, Toxicology, and Pharmacy, University of Veterinary Medicine Hannover, Germany; Center for Systems Neuroscience, Hannover, Germany. Electronic address: wolfgang.loescher@tiho-hannover.de.
Publikováno v: Neuropharmacology [Neuropharmacology] 2020 Dec 01; Vol. 180, pp. 108297. Date of Electronic Publication: 2020 Sep 03.
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7
Akademický článek
Aβ-accelerated neurodegeneration caused by Alzheimer's-associated ACE variant R1279Q is rescued by angiotensin system inhibition in mice.
Autor: Cuddy LK; Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Prokopenko D; Genetics and Aging Unit and McCance Center for Brain Health, Department of Neurology, Massachusetts General Hospital, Boston, MA 02129, USA., Cunningham EP; Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Brimberry R; Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Song P; Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Kirchner R; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Chapman BA; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Hofmann O; Department of Clinical Pathology, University of Melbourne, Victoria 3000, Melbourne, Australia., Hide W; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA., Procissi D; Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Hanania T; PsychoGenics Inc., Paramus, NJ 07652, USA., Leiser SC; PsychoGenics Inc., Paramus, NJ 07652, USA., Tanzi RE; Genetics and Aging Unit and McCance Center for Brain Health, Department of Neurology, Massachusetts General Hospital, Boston, MA 02129, USA. r-vassar@northwestern.edu tanzi@helix.mgh.harvard.edu., Vassar R; Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA. r-vassar@northwestern.edu tanzi@helix.mgh.harvard.edu.; Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Publikováno v: Science translational medicine [Sci Transl Med] 2020 Sep 30; Vol. 12 (563).
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8
Akademický článek
Antisense oligonucleotides increase Scn1a expression and reduce seizures and SUDEP incidence in a mouse model of Dravet syndrome.
Autor: Han Z; Stoke Therapeutics Inc., Bedford, MA 01730, USA., Chen C; Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, USA., Christiansen A; Stoke Therapeutics Inc., Bedford, MA 01730, USA., Ji S; Stoke Therapeutics Inc., Bedford, MA 01730, USA., Lin Q; Stoke Therapeutics Inc., Bedford, MA 01730, USA., Anumonwo C; Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, USA., Liu C; Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, USA., Leiser SC; PsychoGenics Inc., Paramus, NJ 07652, USA., Meena; Stoke Therapeutics Inc., Bedford, MA 01730, USA., Aznarez I; Stoke Therapeutics Inc., Bedford, MA 01730, USA., Liau G; Stoke Therapeutics Inc., Bedford, MA 01730, USA., Isom LL; Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, USA. lisom@umich.edu.
Publikováno v: Science translational medicine [Sci Transl Med] 2020 Aug 26; Vol. 12 (558).
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9
Akademický článek
Acute dosing of vortioxetine strengthens event-related brain activity associated with engagement of attention and cognitive functioning in rats.
Autor: Laursen B; Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Mølleparkvej 4, 9000 Aalborg, Denmark; Department of Synaptic Transmission In vivo, H. Lundbeck A/S, Ottiliavej 9, 2500 Valby, Denmark. Electronic address: XBC@lundbeck.com., Bundgaard CH; Department of Electrical Engineering, Technical University of Denmark, Building 349, Oersteds Plads, 2800 Kgs. Lyngby, Denmark., Graversen C; Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Mølleparkvej 4, 9000 Aalborg, Denmark., Grupe M; Department of Synaptic Transmission In vivo, H. Lundbeck A/S, Ottiliavej 9, 2500 Valby, Denmark., Sanchez C; Brintellix Science Team, H. Lundbeck A/S, Ottiliavej 9, 2500 Valby, Denmark., Leiser SC; Brintellix Science Team, H. Lundbeck A/S, Ottiliavej 9, 2500 Valby, Denmark., Sorensen HBD; Department of Electrical Engineering, Technical University of Denmark, Building 349, Oersteds Plads, 2800 Kgs. Lyngby, Denmark., Drewes AM; Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Mølleparkvej 4, 9000 Aalborg, Denmark., Bastlund JF; Department of Synaptic Transmission In vivo, H. Lundbeck A/S, Ottiliavej 9, 2500 Valby, Denmark.
Publikováno v: Brain research [Brain Res] 2017 Jun 01; Vol. 1664, pp. 37-47. Date of Electronic Publication: 2017 Mar 31.
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10
Akademický článek
The 5-HT 6 receptor antagonist idalopirdine potentiates the effects of donepezil on gamma oscillations in the frontal cortex of anesthetized and awake rats without affecting sleep-wake architecture.
Autor: Amat-Foraster M; Division of Synaptic Transmission, H. Lundbeck A/S, Ottiliavej 9, DK-2500 Valby, Denmark. Electronic address: maaf@lundbeck.com., Leiser SC; Lundbeck Research USA, Inc., Paramus, NJ 07652, USA. Electronic address: stevenleiser@gmail.com., Herrik KF; Division of Synaptic Transmission, H. Lundbeck A/S, Ottiliavej 9, DK-2500 Valby, Denmark. Electronic address: kfh@lundbeck.com., Richard N; Division of Synaptic Transmission, H. Lundbeck A/S, Ottiliavej 9, DK-2500 Valby, Denmark. Electronic address: nelly-richard@hotmail.com., Agerskov C; Division of Synaptic Transmission, H. Lundbeck A/S, Ottiliavej 9, DK-2500 Valby, Denmark. Electronic address: clsg@lundbeck.com., Bundgaard C; Discovery DMPK, H. Lundbeck A/S, Ottiliavej 9, DK-2500 Valby, Denmark. Electronic address: cbun@lundbeck.com., Bastlund JF; Division of Synaptic Transmission, H. Lundbeck A/S, Ottiliavej 9, DK-2500 Valby, Denmark. Electronic address: jfb@lundbeck.com., de Jong IEM; Division of Neurodegeneration, H. Lundbeck A/S, Ottiliavej 9, DK-2500 Valby, Denmark. Electronic address: idj@lundbeck.com.
Publikováno v: Neuropharmacology [Neuropharmacology] 2017 Feb; Vol. 113 (Pt A), pp. 45-59. Date of Electronic Publication: 2016 Sep 16.
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