Zobrazeno 1 - 10 of 26 pro vyhledávání: '"Leisa Jackson"'
1
Akademický článek
Analytic and Clinical Validation of a Pan-Cancer NGS Liquid Biopsy Test for the Detection of Copy Number Amplifications, Fusions and Exon Skipping Variants
Autor: Audrey Audetat, Chérie Tschida, Sarah Kreston, Adam Stephen, Brittany D’Alessio, Madeline Bondy, Leisa Jackson, Hestia Mellert, Niki Givens, Ubaradka G. Sathyanarayana, Gary A. Pestano
Publikováno v: Diagnostics, Vol 12, Iss 3, p 729 (2022)
Liquid biopsies are an integral part of the diagnosis of cancer. Here, we have extended previous validation studies of a new targeted NGS panel to include the detection of copy number amplifications (CNAs), fusions, and exon skipping variants. Detect
Externí odkaz: https://doaj.org/article/cc965d9bf42b4d178be891be87e839f8
Zobrazit plný text záznamu
2
Akademický článek
Targeted Next-Generation Sequencing of Liquid Biopsy Samples from Patients with NSCLC
Autor: Hestia Mellert, Jordan Reese, Leisa Jackson, Victoria Maxwell, Chérie Tschida, Gary A. Pestano
Publikováno v: Diagnostics, Vol 11, Iss 2, p 155 (2021)
Liquid biopsy tests have become an integral part of the molecular diagnosis of patients with non-small cell lung cancer (NSCLC). We describe a new test panel that uses very low input (20 ng) of cell-free nucleic acids extracted from human plasma, whi
Externí odkaz: https://doaj.org/article/87c50d5d684247908d933632be9a9a19
Zobrazit plný text záznamu
3
Abstract 6687: Prevalence of four major gene mutation classes in a survey of ctDNA recovery from early and advanced stage NSCLC
Autor: Claire Gould, Leisa Jackson, Colin Cochran, Audrey Audetat, Brittany D'Alessio, Amanda Weaver, Janice Riley, Gary A. Pestano
Publikováno v: Cancer Research. 83:6687-6687
Introduction: Circulating tumor DNA (ctDNA) has emerged as a powerful biomarker with many applications in oncology including early and late-stage disease prognosis and in treatment decision making. Liquid biopsies have become critical in non-small ce
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::761c63770dd3da0195c2fa6e7139dd70
https://doi.org/10.1158/1538-7445.am2023-6687
Zobrazit plný text záznamu
4
Abstract 5323: Analytic and clinical validation of a new pan-cancer NGS liquid biopsy test for the detection of copy number variations, fusions/exon skipping, somatic variants and indels
Autor: Audrey Audetat, Cherie Tschida, Sarah Kreston, Leisa Jackson, Hestia Mellert, Adam Stephen, Gary A. Pestano
Publikováno v: Cancer Research. 82:5323-5323
Liquid biopsy tests are an integral part of the molecular diagnostic workup of patients with multiple cancer types. We have extended validation studies of a new liquid biopsy test panel that uses an amplicon-based targeted next-generation sequencing
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::219d2aa9b50e3d32b6e5597645c48c7d
https://doi.org/10.1158/1538-7445.am2022-5323
Zobrazit plný text záznamu
5
Targeted Next-Generation Sequencing of Liquid Biopsy Samples from Patients with NSCLC
Autor: Hestia Mellert, Jordan M. Reese, Victoria Maxwell, Gary Pestano, Cherie Tschida, Leisa Jackson
Publikováno v: Diagnostics
Diagnostics, Vol 11, Iss 155, p 155 (2021)
Volume 11
Issue 2
Liquid biopsy tests have become an integral part of the molecular diagnosis of patients with non-small cell lung cancer (NSCLC). We describe a new test panel that uses very low input (20 ng) of cell-free nucleic acids extracted from human plasma, whi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c288e2a70030dab2a14cbe1ff0b86117
https://pubmed.ncbi.nlm.nih.gov/33494470
Zobrazit plný text záznamu
7
Development and Clinical Utility of a Blood-Based Test Service for the Rapid Identification of Actionable Mutations in Non–Small Cell Lung Carcinoma
Autor: Ubaradka G. Sathyanarayana, Kristina Koch, Hestia Mellert, Samantha Cooper, Trudi Foreman, Paula Stonemetz, Scott Thurston, Westen Hahn, Jakkie Greer, Dawne N. Shelton, Dianna Maar, Leisa Jackson, Nicholas F. Dupuis, Gary Pestano, Amanda Weaver
Publikováno v: The Journal of Molecular Diagnostics. 19:404-416
Nearly 80% of cancer patients do not have genetic mutation results available at initial oncology consultation; up to 25% of patients begin treatment before receiving their results. These factors hinder the ability to pursue optimal treatment strategi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a9996e3d72a3208e4fdea996bcf052
https://doi.org/10.1016/j.jmoldx.2016.11.004
Zobrazit plný text záznamu
9
Abstract 3101: Utility of a new targeted next generation sequencing test for liquid biopsy samples from patients with NSCLC
Autor: Jordan M. Reese, Victoria Maxwell, Gary Pestano, Hestia Mellert, Leisa Jackson
Publikováno v: Cancer Research. 80:3101-3101
Blood-based methods for profiling tumor-sourced nucleic acids have become increasingly important in the diagnostic workup for cancer patients, particularly in non-small cell lung cancer (NSCLC). Blood-based assays address several limitations of tissu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8b1f4f424385d3ae436263087d6474fe
https://doi.org/10.1158/1538-7445.am2020-3101
Zobrazit plný text záznamu
10
Abstract B54: Profiling the TCR beta repertoire in liquid biopsies from NSCLC donors
Autor: Benjamin A. Tjoa, Gary Pestano, Hestia Mellert, Leisa Jackson
Publikováno v: Clinical Cancer Research. 26:B54-B54
Introduction: During infection and in cancer, the immune system’s response to antigen leads to changes in the T-cell repertoire. T-cell clonal expansions can be measured by sequencing the antigen-specific loci in the T-Cell Receptor Beta gene (TCR
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::569036545bd29539b0b6b7fd5cd3ce18
https://doi.org/10.1158/1557-3265.liqbiop20-b54
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje