Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Leiore Ajuria"'
1
Akademický článek
SUMOylation in the control of cholesterol homeostasis
Autor: Ana Talamillo, Leiore Ajuria, Marco Grillo, Orhi Barroso-Gomila, Ugo Mayor, Rosa Barrio
Publikováno v: Open Biology, Vol 10, Iss 5 (2020)
SUMOylation—protein modification by the small ubiquitin-related modifier (SUMO)—affects several cellular processes by modulating the activity, stability, interactions or subcellular localization of a variety of substrates. SUMO modification is in
Externí odkaz: https://doaj.org/article/946d77691a644f03bebe7bafffe081d4
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2
Akademický článek
Generation of a versatile BiFC ORFeome library for analyzing protein–protein interactions in live Drosophila
Autor: Johannes Bischof, Marilyne Duffraisse, Edy Furger, Leiore Ajuria, Guillaume Giraud, Solene Vanderperre, Rachel Paul, Mikael Björklund, Damien Ahr, Alexis W Ahmed, Lionel Spinelli, Christine Brun, Konrad Basler, Samir Merabet
Publikováno v: eLife, Vol 7 (2018)
Transcription factors achieve specificity by establishing intricate interaction networks that will change depending on the cell context. Capturing these interactions in live condition is however a challenging issue that requires sensitive and non-inv
Externí odkaz: https://doaj.org/article/4f3279d94fd944efacc4d7695842697f
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3
Akademický článek
A new mode of DNA binding distinguishes Capicua from other HMG-box factors and explains its mutation patterns in cancer.
Autor: Marta Forés, Lucía Simón-Carrasco, Leiore Ajuria, Núria Samper, Sergio González-Crespo, Matthias Drosten, Mariano Barbacid, Gerardo Jiménez
Publikováno v: PLoS Genetics, Vol 13, Iss 3, p e1006622 (2017)
HMG-box proteins, including Sox/SRY (Sox) and TCF/LEF1 (TCF) family members, bind DNA via their HMG-box. This binding, however, is relatively weak and both Sox and TCF factors employ distinct mechanisms for enhancing their affinity and specificity fo
Externí odkaz: https://doaj.org/article/9f0dbfc7c4434685a1c8cb21d12001b1
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4
Akademický článek
Origins of context-dependent gene repression by capicua.
Autor: Marta Forés, Leiore Ajuria, Núria Samper, Sergio Astigarraga, Claudia Nieva, Rona Grossman, Sergio González-Crespo, Ze'ev Paroush, Gerardo Jiménez
Publikováno v: PLoS Genetics, Vol 11, Iss 1, p e1004902 (2015)
Receptor Tyrosine Kinase (RTK) signaling pathways induce multiple biological responses, often by regulating the expression of downstream genes. The HMG-box protein Capicua (Cic) is a transcriptional repressor that is downregulated in response to RTK
Externí odkaz: https://doaj.org/article/df9a41c48481449fa41a6cb4b62a5d3f
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5
Role of a versatile peptide motif controlling Hox nuclear export and autophagy in the Drosophila fat body
Autor: Marilyne Duffraisse, Ingrid Lohmann, Jonathan Reboulet, Julie Carnesecchi, Bruno Hudry, Samir Merabet, Rachel Paul, Agnes Banreti, Leiore Ajuria
Publikováno v: Journal of Cell Science
Journal of Cell Science, Company of Biologists, 2020, 133 (18), pp.jcs241943. ⟨10.1242/jcs.241943⟩
Journal of Cell Science, Company of Biologists, 2020
Journal of Cell Science, 2020, 133 (18), pp.jcs241943. ⟨10.1242/jcs.241943⟩
International audience; Hox proteins are major regulators of embryonic development, acting in the nucleus to regulate the expression of their numerous downstream target genes. By analyzing deletion forms of the Drosophila Hox protein Ultrabithorax (U
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36ba514bffbb10320dd488f0a0342a93
https://hal.archives-ouvertes.fr/hal-03064360
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6
The role of SUMOylation during development
Autor: Ana Talamillo, Rosa Barrio, Leiore Ajuria, Immacolata Giordano, Orhi Barroso-Gomila, Ugo Mayor, Marco Grillo
Publikováno v: Addi. Archivo Digital para la Docencia y la Investigación
instname
Biochemical Society Transactions
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
During the development of multicellular organisms, transcriptional regulation plays an important role in the control of cell growth, differentiation and morphogenesis. SUMOylation is a reversible post-translational process involved in transcriptional
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5502a8d68c18a89eebf5af189986f6
https://zenodo.org/record/4327636
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8
Role of a versatile peptide motif controlling Hox nuclear export and autophagy in the
Autor: Marilyne, Duffraisse, Rachel, Paul, Julie, Carnesecchi, Bruno, Hudry, Agnes, Banreti, Jonathan, Reboulet, Leiore, Ajuria, Ingrid, Lohmann, Samir, Merabet
Publikováno v: Journal of cell science. 133(18)
Hox proteins are major regulators of embryonic development, acting in the nucleus to regulate the expression of their numerous downstream target genes. By analyzing deletion forms of the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cd0077446bcf6fc2f2b9888b63585c25
https://pubmed.ncbi.nlm.nih.gov/32878938
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9
Role of a versatile peptide motif in controlling Hox nuclear export and autophagy in the Drosophila fat body
Autor: Jonathan Reboulet, Rachel E. Paul, Marilyne Duffraisse, Ingrid Lohmann, Samir Merabet, Julie Carnesecchi, Leiore Ajuria, Agnes Banretti, Bruno Hudry
Hox proteins are major regulators of embryonic development, acting in the nucleus to regulate the expression of their numerous downstream target genes. By analyzing deleted forms of theDrosophilaHox protein Ultrabithorax (Ubx), we revealed the presen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8a273de471aaaf99d58f9687e2a8c4b
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10
Generation of a versatile BiFC ORFeome library for analyzing protein-protein interactions in live Drosophila
Autor: Solene Vanderperre, Lionel Spinelli, Damien Ahr, Marilyne Duffraisse, Guillaume Giraud, Samir Merabet, Mikael Björklund, Leiore Ajuria, Konrad Basler, Rachel E. Paul, Christine Brun, Alexis W Ahmed, Johannes Bischof, Edy Furger
Publikováno v: eLife
eLife, eLife Sciences Publication, 2018, 7, ⟨10.7554/eLife.38853⟩
eLife, 2018, 7, ⟨10.7554/eLife.38853⟩
eLife, Vol 7 (2018)
Transcription factors achieve specificity by establishing intricate interaction networks that will change depending on the cell context. Capturing these interactions in live condition is however a challenging issue that requires sensitive and non-inv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212f2890cdae4a9491655368681eaaca
https://hal-amu.archives-ouvertes.fr/hal-01882683
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