Factor XII promotes the thromboinflammatory response in a rat model of venoarterial extracorporeal membrane oxygenation.

Autor: Kharnaf M; The Heart Institute, Cincinnati Children's Hospital Medical Center and The University of Cincinnati College of Medicine, Cincinnati, Ohio. Electronic address: moosakernaf@gmail.com., Zafar F; The Heart Institute, Cincinnati Children's Hospital Medical Center and The University of Cincinnati College of Medicine, Cincinnati, Ohio., Hogue S; The Heart Institute, Cincinnati Children's Hospital Medical Center and The University of Cincinnati College of Medicine, Cincinnati, Ohio., Rosenfeldt L; Cancer and Blood Disease Institute, Cincinnati Children's Hospital Medical Center and The University of Cincinnati College of Medicine, Cincinnati, Ohio., Cantrell RL; Cancer and Blood Disease Institute, Cincinnati Children's Hospital Medical Center and The University of Cincinnati College of Medicine, Cincinnati, Ohio., Sharma BK; Cancer and Blood Disease Institute, Cincinnati Children's Hospital Medical Center and The University of Cincinnati College of Medicine, Cincinnati, Ohio., Pearson A; Cancer and Blood Disease Institute, Cincinnati Children's Hospital Medical Center and The University of Cincinnati College of Medicine, Cincinnati, Ohio., Sprague C; Cancer and Blood Disease Institute, Cincinnati Children's Hospital Medical Center and The University of Cincinnati College of Medicine, Cincinnati, Ohio., Leino D; Department of Pathology, Cincinnati Children's Hospital Medical Center and The University of Cincinnati College of Medicine, Cincinnati, Ohio., Abplanalp WA; The Heart Institute, Cincinnati Children's Hospital Medical Center and The University of Cincinnati College of Medicine, Cincinnati, Ohio., Zelek WM; Systems Immunity Research Institute and Dementia Research Institute, Cardiff University, Cardiff, United Kingdom., McCrae KR; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, Ohio., Shim YJ; Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, Ohio., Morales D; The Heart Institute, Cincinnati Children's Hospital Medical Center and The University of Cincinnati College of Medicine, Cincinnati, Ohio., Tweddell J; The Heart Institute, Cincinnati Children's Hospital Medical Center and The University of Cincinnati College of Medicine, Cincinnati, Ohio., Qualls JE; Department of Biological Sciences, St Elizabeth College of Natural and Health Sciences, Thomas More University, Crestview Hills, Ky., Palumbo JS; Cancer and Blood Disease Institute, Cincinnati Children's Hospital Medical Center and The University of Cincinnati College of Medicine, Cincinnati, Ohio. Electronic address: joe.palumbo@cchmc.org.

Publikováno v: The Journal of thoracic and cardiovascular surgery [J Thorac Cardiovasc Surg] 2024 Aug; Vol. 168 (2), pp. e37-e53. Date of Electronic Publication: 2023 Sep 07.

Transcriptome analysis in acute gastrointestinal graft- versus host disease reveals a unique signature in children and shared biology with pediatric inflammatory bowel disease.

Autor: Khandelwal P; Division of Bone Marrow Transplant and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati OH 45229. Pooja.khandelwal@cchmc.org., Lounder DT; Division of Bone Marrow Transplant and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati OH 45229., Bartlett A; Division of Bone Marrow Transplant and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati OH 45229., Haberman Y; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati OH 45229; Division of Gastroenterology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229; Sheba Medical Center, Hashomer, affiliated with the Aviv University, Israel 52620., Jegga AG; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati OH 45229; Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229., Ghandikota S; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati OH 45229; Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229., Koo J; Division of Bone Marrow Transplant and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati OH 45229., Luebbering N; Division of Bone Marrow Transplant and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati OH 45229., Leino D; Department of Pathology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229., Abdullah S; Division of Bone Marrow Transplant and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati OH 45229., Loveless M; Division of Bone Marrow Transplant and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati OH 45229., Minar P; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati OH 45229; Division of Gastroenterology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229., Lake K; Division of Bone Marrow Transplant and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati OH 45229., Litts B; Division of Bone Marrow Transplant and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati OH 45229., Karns R; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati OH 45229; Division of Gastroenterology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229., Nelson AS; Division of Bone Marrow Transplant and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati OH 45229., Denson LA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati OH 45229; Division of Gastroenterology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229., Davies SM; Division of Bone Marrow Transplant and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati OH 45229.

Publikováno v: Haematologica [Haematologica] 2023 Jul 01; Vol. 108 (7), pp. 1803-1816. Date of Electronic Publication: 2023 Jul 01.

Lethal Pediatric Cerebral Vasculitis Triggered by Severe Acute Respiratory Syndrome Coronavirus 2.

Autor: Poisson KE; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Child Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Zygmunt A; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Child Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Leino D; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Pathology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Fuller CE; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Pathology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Department of Pathology, State University of New York, Upstate Medical University, Syracuse, New York., Jones BV; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Haslam D; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Infectious Disease, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Staat MA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Infectious Disease, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Clay G; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Ting TV; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Wesselkamper K; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Child Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Hallinan B; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Child Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Standridge S; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Child Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Day ME; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., McNeal M; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Infectious Disease, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Stevenson CB; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Neurosurgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Vawter-Lee M; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Child Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio. Electronic address: Marissa.Vawter@cchmc.org.

Publikováno v: Pediatric neurology [Pediatr Neurol] 2022 Feb; Vol. 127, pp. 1-5. Date of Electronic Publication: 2021 Nov 12.

A Novel Monoclonal Antibody against PD-1 for the Treatment of Viral Oncogene-Induced Tumors or Other Cancer.

Autor: Xu, Xu¹ (AUTHOR) sue_xu01@hotmail.com, Yan, Shih-Long¹ (AUTHOR), Yo, Yi-Te¹ (AUTHOR), Chiang, Peiyu¹ (AUTHOR), Tsai, Chan-Yen² (AUTHOR), Lin, Lih-Ling¹ (AUTHOR), Qin, Albert² (AUTHOR) sue_xu01@hotmail.com

Publikováno v: Cancers. Sep2024, Vol. 16 Issue 17, p3052. 17p.

Collagen COL22A1 maintains vascular stability and mutations in COL22A1 are potentially associated with intracranial aneurysms.

Autor: Ton QV; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Leino D; Division of Pathology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA., Mowery SA; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Bredemeier NO; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA., Lafontant PJ; Department of Biology, DePauw University, Greencastle, IN 46135, USA., Lubert A; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Gurung S; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Farlow JL; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Foroud TM; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Broderick J; Department of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, OH 45267, USA., Sumanas S; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA saulius.sumanas@cchmc.org.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.

Publikováno v: Disease models & mechanisms [Dis Model Mech] 2018 Dec 12; Vol. 11 (12). Date of Electronic Publication: 2018 Dec 12.