Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Leiming Guo"'
Autor:
Lingling Tian MS, Ronghu Mao MM, Dingjie Li MM, Wei Guo MD, Bing Li MD, Zhaoyang Lou MD, Leiming Guo MM
Publikováno v:
Technology in Cancer Research & Treatment, Vol 23 (2024)
Objective To investigate the effect of various frequencies of bolus use on the superficial dose of volumetric modulated arc therapy after modified radical mastectomy for breast cancer. Methods Based on the computed tomography images of a female anthr
Externí odkaz:
https://doaj.org/article/24e5017044864bdeb02b36d6d7d71a41
Autor:
Yang Wang, Tianyu Yu, Yi Han, Yazhi He, Yiran Song, Leiming Guo, Liwei An, Chunying Yang, Feng Wang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The spindle assembly checkpoint (SAC) is a critical monitoring device in mitosis for the maintenance of genomic stability. Specifically, the SAC complex comprises several factors, including Mad1, Mad2, and Bub1. Ataxia-telangiectasia mutated (ATM) ki
Externí odkaz:
https://doaj.org/article/8579124afe454514b19b8c08832da250
Autor:
Jiehan Li, Guang Luo, Chuchu Zhang, Shuaiyu Long, Leiming Guo, Ge Yang, Feng Wang, Lingling Zhang, Liyang Shi, Yang Fu, Yingjie Zhang
Publikováno v:
Materials Today Bio, Vol 14, Iss , Pp 100238- (2022)
Melanoma is a highly aggressive tumor located in the skin, with limited traditional therapies. In order to reduce the side effects caused by traditional administration method and amplify the killing effect of immune system against tumor cells, an in
Externí odkaz:
https://doaj.org/article/5eb8ea7f390c4f1d97e4a4bb6c7f906f
Publikováno v:
Cellular Physiology and Biochemistry, Vol 51, Iss 5, Pp 2212-2223 (2018)
Background/Aims: TNF-related apoptosis-inducing ligand (TRAIL) is a novel and low-toxic anti-tumor drug used for various cancers. However, cancer cells usually develop mechanisms to acquire the resistance against TRAIL. Among these changes, dysregula
Externí odkaz:
https://doaj.org/article/8ca886a04ce94086b61539d37618722a
Publikováno v:
The Innovation, Vol 2, Iss 1, Pp 100088- (2021)
Summary: Thin polymer coatings covering on porous substrates are a common composite structure required in numerous applications, including membrane separation, and there is a strong need to push the coating thicknesses down to the nanometer scale to
Externí odkaz:
https://doaj.org/article/7671bcbbf887476399236b5cad9a079f
Publikováno v:
Chinese Journal of Lung Cancer, Vol 21, Iss 5, Pp 383-388 (2018)
Background and objective The main manifestations of radiation pneumonitis are injury of alveolar epithelial and endothelial cells, abnormal expression of cytokines, abnormal proliferation of fibroblasts and synthesis of fibrous matrix. The occurrence
Externí odkaz:
https://doaj.org/article/0b2fdccb6e994b8fae733c3f5d1b906a
Publikováno v:
Pharmaceutics, Vol 11, Iss 2, p 98 (2019)
Here, we have presented the development of a systems pharmacokinetics-pharmacodynamics (PK-PD) model for antibody-drug conjugates (ADCs), which uses intracellular target occupancy to drive in-vivo efficacy. The model is built based on PK and efficacy
Externí odkaz:
https://doaj.org/article/4291c1938749488fa8630dc64bde2251
Publikováno v:
Journal of Pharmaceutical Sciences.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e431f1b5b60dc8ba9e3a67b3650a2bb
https://doi.org/10.1016/j.xphs.2023.04.006
https://doi.org/10.1016/j.xphs.2023.04.006
Autor:
Nannan Liu, Xinxiu Jiang, Leiming Guo, Chuchu Zhang, Meimei Jiang, Zhuoran Sun, Yizheng Zhang, Wunan Mi, Jiehan Li, Yang Fu, Feng Wang, Lingling Zhang, Yingjie Zhang
Publikováno v:
International Journal of Biological Sciences. 18:2419-2438
The most frequent genetic alterations of the TP53 gene in human cancer were reported. TP53 mutation gains new function as a target of genetic instability, which is associated with increased tumor progression and poor survival rate in patients. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c9ac3cafaef640afbf324d4d7bc8bc
https://doi.org/10.7150/ijbs.67200
https://doi.org/10.7150/ijbs.67200
Autor:
Leiming Guo, Konstantinos Ntetsikas, Georgios Zapsas, Roshni Thankamony, Zhiping Lai, Nikos Hadjichristidis
Publikováno v:
Angewandte Chemie International Edition. 62
The great significance of boosting the design of percolating nanopore structures in block copolymers (BCPs) for varied use cases has been widely demonstrated in the past several decades. However, it still remains challenging to prepare the desired po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88e28e8ffc4b7b962374cdff6517d0c6
https://doi.org/10.1002/anie.202212400
https://doi.org/10.1002/anie.202212400