Zobrazeno 1 - 10
of 319
pro vyhledávání: '"Leilei Shi"'
Publikováno v:
Big Data Mining and Analytics, Vol 7, Iss 2, Pp 357-370 (2024)
Grid-based recommendation algorithms view users and items as abstract nodes, and the information utilised by the algorithm is hidden in the selection relationships between users and items. Although these relationships can be easily handled, much usef
Externí odkaz:
https://doaj.org/article/7b215583182f43d9b6e28d6b5d2673e7
Autor:
Wei He, Weiyi Peng, Si Chen, Jordi Rodon Ahnert, Jiakai Hou, Leilei Shi, Ritu Bohat, Yue Lu, Han Xu, Sana Sharif, Roshni Jaffery, Ashley Guerrero, Rongjie Fu, Ningbo Zheng, Nicholas A Egan, Chengtai Yu, Shuyue Wang, Donjeta Gjuka, Everett M Stone, Pooja Anil Shah, Taiping Chen, Xinli Liu, Mark T Bedford
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 9 (2024)
Background Hyperactivated protein arginine methyltransferases (PRMTs) are implicated in human cancers. Inhibiting tumor intrinsic PRMT5 was reported to potentiate antitumor immune responses, highlighting the possibility of combining PRMT5 inhibitors
Externí odkaz:
https://doaj.org/article/f2ce79b83742456784a1825a87418410
Publikováno v:
Ecological Informatics, Vol 82, Iss , Pp 102782- (2024)
Water bodies are crucial components of urban ecology. The development of rapid and timely water-quality assessment tools using easily measured variables is essential for the health management of urban water bodies. In this study, we focused on the di
Externí odkaz:
https://doaj.org/article/eeb40c38f4dc482d9ca3fc7062d31d2d
Autor:
Zixuan Han, Leilei Shi, Lu Liu, Liang Jiang, Jiawei Fang, Fanyuan Lin, Jinjuan Zhang, John Panneerselvam, Nick Antonopoulos
Publikováno v:
Big Data Mining and Analytics, Vol 7, Iss 1, Pp 217-243 (2024)
Social networks are inevitable parts of our daily life, where an unprecedented amount of complex data corresponding to a diverse range of applications are generated. As such, it is imperative to conduct research on social events and patterns from the
Externí odkaz:
https://doaj.org/article/5df577c063bc46ef97d6bd3e5d56c47c
Autor:
Lavanya Gunamalai, Parul Singh, Brian Berg, Leilei Shi, Ernesto Sanchez, Alexa Smith, Ghislain Breton, Mark T. Bedford, Darius Balciunas, Ashish Kapoor
Publikováno v:
HGG Advances, Vol 6, Iss 1, Pp 100358- (2025)
Summary: Several empirical and theoretical studies suggest the presence of multiple enhancers per gene that collectively regulate gene expression, and that common sequence variation impacting on the activities of these enhancers is a major source of
Externí odkaz:
https://doaj.org/article/b8653cdc1e774e4ebcd1bd92602ac403
Autor:
Lulu Huang, Tongyi Zhao, Weijun Zhao, Andong Shao, Huajun Zhao, Wenxuan Ma, Yingfei Gong, Xianhuan Zeng, Changzhen Weng, Lingling Bu, Zhenhua Di, Shiyu Sun, Qinsheng Dai, Minhui Sun, Limei Wang, Zhenguang Liu, Leilei Shi, Jiesen Hu, Shentong Fang, Cheng Zhang, Jian Zhang, Guan Wang, Karin Loré, Yong Yang, Ang Lin
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
ABSTRACTHerpes zoster remains an important global health issue and mainly occurs in aged and immunocompromised individuals with an early exposure history to Varicella Zoster Virus (VZV). Although the licensed vaccine Shingrix has remarkably high effi
Externí odkaz:
https://doaj.org/article/10860985a51042b89c1e33835ed869db
Autor:
Yalong Wang, Jujun Zhou, Wei He, Rongjie Fu, Leilei Shi, Ngoc Khoi Dang, Bin Liu, Han Xu, Xiaodong Cheng, Mark T. Bedford
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114459- (2024)
Summary: Glycine- and arginine-rich (GAR) motifs, commonly found in RNA-binding and -processing proteins, can be symmetrically (SDMA) or asymmetrically (ADMA) dimethylated at the arginine residue by protein arginine methyltransferases. Arginine-methy
Externí odkaz:
https://doaj.org/article/5c587f8358ad489fb96eee0591ea2a7f
Autor:
Huajun Zhao, Xianyu Shao, Yating Yu, Lulu Huang, Narh Philip Amor, Kun Guo, Changzhen Weng, Weijun Zhao, Ailu Yang, Jiesen Hu, Hongbao Yang, Zhenguang Liu, Qiuju Han, Leilei Shi, Shiyu Sun, Jian Zhang, Ang Lin, Yong Yang
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-6 (2024)
Abstract Here we report on the development and comprehensive evaluations of an mRNA vaccine for chronic hepatitis B (CHB) treatment. In two different HBV carrier mouse models generated by viral vector-mediated HBV transfection (pAAV-HBV1.2 and rAAV8-
Externí odkaz:
https://doaj.org/article/123c1f181be54534b59d5e7b9a9054fd
Autor:
Wei Lu, Jixian Zhang, Weifeng Huang, Ziqiao Zhang, Xiangyu Jia, Zhenyu Wang, Leilei Shi, Chengtao Li, Peter G. Wolynes, Shuangjia Zheng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract While significant advances have been made in predicting static protein structures, the inherent dynamics of proteins, modulated by ligands, are crucial for understanding protein function and facilitating drug discovery. Traditional docking m
Externí odkaz:
https://doaj.org/article/6ca6cab59f314b1db99f1750b5c28541
Publikováno v:
IET Power Electronics, Vol 16, Iss 16, Pp 2638-2649 (2023)
Abstract Buck converter is a good candidate for the non‐isolated auxiliary power supply (APS) due to its simple structure and high efficiency. However, it can hardly be adopted in applications that required a very high step‐down ratio due to the
Externí odkaz:
https://doaj.org/article/b3b47622e5cf431195aba8e3db1d08d5