Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Leilei Ai"'
Autor:
Yingyan Chen, Leilei Ai, Yingyi Zhang, Xiang Li, Shiqian Xu, Weijie Yang, Jiamin Jin, Yerong Ma, Zhanhong Hu, Yinli Zhang, Yan Rong, Songying Zhang
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract Chemotherapy-induced ovarian damage and infertility are significant concerns for women of childbearing age with cancer; however, the underlying mechanisms are still not fully understood. Our study has revealed a close association between epi
Externí odkaz:
https://doaj.org/article/37f200ab515145faa77e3af533c050da
Autor:
Liyu Jiang, Yan Zeng, Leilei Ai, Hao Yan, Xiaochun Yang, Peihua Luo, Bo Yang, Zhifei Xu, Qiaojun He
Publikováno v:
Biochemical pharmacology. 201
The application of lapatinib, a widely used dual inhibitor of human epidermal growth factor receptor 1 (EGFR/ERBB1) and 2 (HER2/ERBB2), has been seriously limited due to cutaneous toxicity. However, the specific mechanism of lapatinib-induced cutaneo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e94cd9a23634581bc9afe09e65765aea
https://pubmed.ncbi.nlm.nih.gov/35617997
https://pubmed.ncbi.nlm.nih.gov/35617997
Publikováno v:
Drug Design, Development and Therapy. 14:3625-3649
PD-1/PD-L1 inhibitors are a group of immune checkpoint inhibitors as front-line treatment of multiple types of cancer. However, the serious immune-related adverse reactions limited the clinical application of PD-1/PD-L1 monoclonal antibodies, despite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::812e141dbb7ba044a64f7b33566f17df
https://doi.org/10.2147/dddt.s267433
https://doi.org/10.2147/dddt.s267433
Autor:
Liyu Jiang, Yan Zeng, Leilei Ai, Hao Yan, Xiaochun Yang, Peihua Luo, Bo Yang, Zhifei Xu, Qiaojun He
Background and Purpose Lapatinib, a widely-used dual inhibitor of EGFR/ERBB1 and HER2/ERBB2 effectively targeting HER2 positive breast cancer, has been seriously limited due to cutaneous toxicity. However, the specific mechanism of lapatinib-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703c82819186a688f228e6690b9523c7
https://doi.org/10.21203/rs.3.rs-1461458/v1
https://doi.org/10.21203/rs.3.rs-1461458/v1
Publikováno v:
Expert Review of Clinical Pharmacology. 12:1121-1127
Introduction: Sorafenib is a multitargeted tyrosine kinase inhibitor, which has been mainly used in the treatment of advanced hepatocellular carcinoma and renal cancer. However, hand-foot skin reaction (HFSR), as one of the most common adverse reacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f10e41fe15f8d5ab4697f761d07e84
https://doi.org/10.1080/17512433.2019.1689122
https://doi.org/10.1080/17512433.2019.1689122
Publikováno v:
Expert Review of Clinical Pharmacology
The outbreak of COVID-19 caused by SARS-CoV-2 infection has become a serious hazard to global health. Apart from attacking respiratory system, it can induce multiorgan dysfunction, including cardiovascular system, liver, kidney, gastrointestinal, ner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd3d73d6f32ce37d4d6f0c9bf14c6bd
https://pubmed.ncbi.nlm.nih.gov/32896175
https://pubmed.ncbi.nlm.nih.gov/32896175
Publikováno v:
2014 12th IEEE International Conference on Solid-State and Integrated Circuit Technology (ICSICT).
Negative bias temperature instability (NBTI) as one of CMOS device degradations has been extensively researched. Based on the theories of NBTI degradations, we optimize a reliability model for the frequency degradation of the ring oscillator (RO), an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23a5faa4a15c21d050e7de5c5d92de9f
https://doi.org/10.1109/icsict.2014.7021670
https://doi.org/10.1109/icsict.2014.7021670