Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Leilei Ai"'
Autor:
Yingyan Chen, Leilei Ai, Yingyi Zhang, Xiang Li, Shiqian Xu, Weijie Yang, Jiamin Jin, Yerong Ma, Zhanhong Hu, Yinli Zhang, Yan Rong, Songying Zhang
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract Chemotherapy-induced ovarian damage and infertility are significant concerns for women of childbearing age with cancer; however, the underlying mechanisms are still not fully understood. Our study has revealed a close association between epi
Externí odkaz:
https://doaj.org/article/37f200ab515145faa77e3af533c050da
Autor:
Liyu Jiang, Yan Zeng, Leilei Ai, Hao Yan, Xiaochun Yang, Peihua Luo, Bo Yang, Zhifei Xu, Qiaojun He
Publikováno v:
Biochemical pharmacology. 201
The application of lapatinib, a widely used dual inhibitor of human epidermal growth factor receptor 1 (EGFR/ERBB1) and 2 (HER2/ERBB2), has been seriously limited due to cutaneous toxicity. However, the specific mechanism of lapatinib-induced cutaneo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e94cd9a23634581bc9afe09e65765aea
https://pubmed.ncbi.nlm.nih.gov/35617997
https://pubmed.ncbi.nlm.nih.gov/35617997
Publikováno v:
Drug Design, Development and Therapy. 14:3625-3649
PD-1/PD-L1 inhibitors are a group of immune checkpoint inhibitors as front-line treatment of multiple types of cancer. However, the serious immune-related adverse reactions limited the clinical application of PD-1/PD-L1 monoclonal antibodies, despite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::812e141dbb7ba044a64f7b33566f17df
https://doi.org/10.2147/dddt.s267433
https://doi.org/10.2147/dddt.s267433
Autor:
Liyu Jiang, Yan Zeng, Leilei Ai, Hao Yan, Xiaochun Yang, Peihua Luo, Bo Yang, Zhifei Xu, Qiaojun He
Background and Purpose Lapatinib, a widely-used dual inhibitor of EGFR/ERBB1 and HER2/ERBB2 effectively targeting HER2 positive breast cancer, has been seriously limited due to cutaneous toxicity. However, the specific mechanism of lapatinib-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703c82819186a688f228e6690b9523c7
https://doi.org/10.21203/rs.3.rs-1461458/v1
https://doi.org/10.21203/rs.3.rs-1461458/v1
Publikováno v:
Expert Review of Clinical Pharmacology. 12:1121-1127
Introduction: Sorafenib is a multitargeted tyrosine kinase inhibitor, which has been mainly used in the treatment of advanced hepatocellular carcinoma and renal cancer. However, hand-foot skin reaction (HFSR), as one of the most common adverse reacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f10e41fe15f8d5ab4697f761d07e84
https://doi.org/10.1080/17512433.2019.1689122
https://doi.org/10.1080/17512433.2019.1689122
Publikováno v:
Expert Review of Clinical Pharmacology
The outbreak of COVID-19 caused by SARS-CoV-2 infection has become a serious hazard to global health. Apart from attacking respiratory system, it can induce multiorgan dysfunction, including cardiovascular system, liver, kidney, gastrointestinal, ner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd3d73d6f32ce37d4d6f0c9bf14c6bd
https://pubmed.ncbi.nlm.nih.gov/32896175
https://pubmed.ncbi.nlm.nih.gov/32896175
Publikováno v:
2014 12th IEEE International Conference on Solid-State and Integrated Circuit Technology (ICSICT).
Negative bias temperature instability (NBTI) as one of CMOS device degradations has been extensively researched. Based on the theories of NBTI degradations, we optimize a reliability model for the frequency degradation of the ring oscillator (RO), an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23a5faa4a15c21d050e7de5c5d92de9f
https://doi.org/10.1109/icsict.2014.7021670
https://doi.org/10.1109/icsict.2014.7021670
Autor:
Chen, Yingyan, Ai, Leilei, Zhang, Yingyi, Li, Xiang, Xu, Shiqian, Yang, Weijie, Jin, Jiamin, Ma, Yerong, Hu, Zhanhong, Zhang, Yinli, Rong, Yan, Zhang, Songying
Publikováno v:
Cell Death Discovery; 11/14/2023, Vol. 9 Issue 1, p1-13, 13p
Autor:
Li, Hui1 (AUTHOR) ray@mail.buct.edu.cn, Li, Tianwei2 (AUTHOR)
Publikováno v:
Advances in Difference Equations. 12/11/2019, Vol. 2019 Issue 1, p1-14. 14p.
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 14, Pp 3625-3649 (2020)
Leilei Ai, Jian Chen, Hao Yan, Qiaojun He, Peihua Luo, Zhifei Xu, Xiaochun Yang Center for Drug Safety Evaluation and Research of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, People’s Republic of Ch
Externí odkaz:
https://doaj.org/article/485ab1a8bbf0453584cc07eeb3df6967