Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Leilei, Wen"'
Publikováno v:
Shuitu baochi tongbao, Vol 43, Iss 1, Pp 417-423 (2023)
[Objective] Measures of national key soil and water conservation projects (NKSWCP) were systematically evaluated to provide a basis for improving the quality and efficiency of soil and water loss control in the black soil area of Northeast China, and
Externí odkaz:
https://doaj.org/article/2a0b75924e764c03932d6121eaea9ae0
Autor:
Xiaojing Zhang, Jiali Zhang, Zhaobing Pan, Yuxi Zhang, Xiaoqing Xu, Yujun Sheng, Zhengwei Zhu, Fusheng Zhou, Leilei Wen
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by the production of autoantibodies, immune complex deposition, and tissue/organ damage. In this study, we aimed to identify molecular features and signaling pat
Externí odkaz:
https://doaj.org/article/e0d937967d154372b29d962cc38b3a07
Autor:
Kangkang Song, Xiaodong Zheng, Xiaomin Liu, Yujun Sheng, Lu Liu, Leilei Wen, Shunlai Shang, Yiyao Deng, Qing Ouyang, Xuefeng Sun, Qinggang Li, Pu Chen, Guangyan Cai, Mengyun Chen, Yuanjing Zhang, Bo Liang, Jianglin Zhang, Xuejun Zhang, Xiangmei Chen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundLupus nephritis (LN) is one of the most common and serious complications of systemic lupus erythaematosus (SLE). Genetic factors play important roles in the pathogenesis of LN and could be used to predict who might develop LN. The purpose o
Externí odkaz:
https://doaj.org/article/a4ebec050f7342b78ed1b479849e407c
Autor:
Yujun Sheng, Leilei Wen, Xiaodong Zheng, Mengqing Li, Dan Wang, Sixian Chen, Ran Li, Lili Tang, Fusheng Zhou
Publikováno v:
Epigenetics, Vol 16, Iss 6, Pp 618-628 (2021)
Psoriasis is an autoimmune skin disorder influenced by genetic, epigenetic and environmental factors. We previously found CYP2S1 intragenic DNA methylation cg19430423 site strongly hypomethylated in psoriatic skin tissues. In this study, we performed
Externí odkaz:
https://doaj.org/article/071b49c2f5564aaebe439aa362ca5e20
Autor:
Yujun Sheng, Jiali Zhang, Keke Li, Hongyan Wang, Wenjun Wang, Leilei Wen, Jinping Gao, Xianfa Tang, Huayang Tang, He Huang, Minglong Cai, Tao Yuan, Lu Liu, Xiaodong Zheng, Zhengwei Zhu, Yong Cui
Publikováno v:
FEBS Open Bio, Vol 11, Iss 2, Pp 395-403 (2021)
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by abnormal activation of T cells and caused by an imbalance in the production and clearance of apoptotic cells. We previously showed that the transcription regulator Ba
Externí odkaz:
https://doaj.org/article/2143e338bf8040c5978eaf4f37243b3b
Publikováno v:
Journal of Bio-X Research, Vol 2, Iss 3, Pp 112-120 (2019)
Abstract. The human leukocyte antigen (HLA) complex is involved in immunity, belongs to a highly polymorphic family of genes, and is found in a disease-associated region of the human genome. The HLA region of the genome has been associated with more
Externí odkaz:
https://doaj.org/article/ab06a7ab8b7b4c339730b19ee3a0315b
Autor:
Changbing Shen, Leilei Wen, Randy Ko, Jing Gao, Xue Shen, Xianbo Zuo, Liangdan Sun, Yi-Hsiang Hsu, Xuejun Zhang, Yong Cui, Meng Wang, Fusheng Zhou
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-7 (2018)
Abstract Background Psoriasis (Ps) is a common chronic inflammatory skin disease. The keratinocytes of psoriatic skin defy normal apoptosis and exhibit active cell proliferation. Aberrant DNA methylation (DNAm) has been suggested relevant through reg
Externí odkaz:
https://doaj.org/article/e109cb95e22448dcbdb025024ecd3584
Autor:
Xianyong, Yin, Kwangwoo, Kim, Hiroyuki, Suetsugu, So-Young, Bang, Leilei, Wen, Masaru, Koido, Eunji, Ha, Lu, Liu, Yuma, Sakamoto, Sungsin, Jo, Rui-Xue, Leng, Nao, Otomo, Young-Chang, Kwon, Yujun, Sheng, Nobuhiko, Sugano, Mi Yeong, Hwang, Weiran, Li, Masaya, Mukai, Kyungheon, Yoon, Minglong, Cai, Kazuyoshi, Ishigaki, Won Tae, Chung, He, Huang, Daisuke, Takahashi, Shin-Seok, Lee, Mengwei, Wang, Kohei, Karino, Seung-Cheol, Shim, Xiaodong, Zheng, Tomoya, Miyamura, Young Mo, Kang, Dongqing, Ye, Junichi, Nakamura, Chang-Hee, Suh, Yuanjia, Tang, Goro, Motomura, Yong-Beom, Park, Huihua, Ding, Takeshi, Kuroda, Jung-Yoon, Choe, Chengxu, Li, Hiroaki, Niiro, Youngho, Park, Changbing, Shen, Takeshi, Miyamoto, Ga-Young, Ahn, Wenmin, Fei, Tsutomu, Takeuchi, Jung-Min, Shin, Keke, Li, Yasushi, Kawaguchi, Yeon-Kyung, Lee, Yong-Fei, Wang, Koichi, Amano, Dae Jin, Park, Wanling, Yang, Yoshifumi, Tada, Yu Lung, Lau, Ken, Yamaji, Zhengwei, Zhu, Masato, Shimizu, Takashi, Atsumi, Akari, Suzuki, Takayuki, Sumida, Yukinori, Okada, Koichi, Matsuda, Keitaro, Matsuo, Yuta, Kochi, Kazuhiko, Yamamoto, Koichiro, Ohmura, Tae-Hwan, Kim, Sen, Yang, Takuaki, Yamamoto, Bong-Jo, Kim, Nan, Shen, Shiro, Ikegawa, Hye-Soon, Lee, Xuejun, Zhang, Chikashi, Terao, Yong, Cui, Sang-Cheol, Bae
Publikováno v:
Annals of the Rheumatic Diseases. 81:1273-1280
ObjectiveGenome-wide association studies (GWAS) have identified >100 risk loci for systemic lupus erythematosus (SLE), but the disease genes at most loci remain unclear, hampering translation of these genetic discoveries. We aimed to prioritise genes
Autor:
Lu Liu, Xianyong Yin, Leilei Wen, Chao Yang, Yujun Sheng, Yan Lin, Zhengwei Zhu, Changbing Shen, Yinjuan Shi, Yajie Zheng, Sen Yang, Xuejun Zhang, Yong Cui
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 6, Pp 1503-1511 (2016)
We aimed to elucidate the cell types, tissues, and pathways influenced by common variants in systemic lupus erythematosus (SLE). We applied a nonparameter enrichment statistical approach, termed SNPsea, in 181 single nucleotide polymorphisms (SNPs) t
Externí odkaz:
https://doaj.org/article/2686b75ee1ae4f42a3495a137c5e9500
Autor:
Jinfa Dou, Huimin Guo, Fang Cheng, Hequn Huang, Liying Fu, Longnian Li, Chao Yang, Lei Ye, Leilei Wen, Yuyan Cheng, Lili Tang, Caihong Zhu, Zhengwei Zhu, Wenjun Wang, Yujun Sheng, Zaixing Wang, Shengxiu Liu, Xing Fan, Xianbo Zuo, Fusheng Zhou, Liangdan Sun, Xiaodong Zheng, Xuejun Zhang
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186067 (2017)
Researchers have learned that nearly all conditions and diseases have a genetic component. With the benefit of technological advances, many single-nucleotide polymorphisms (SNPs) have been found to be associated with the risk of complex disorders by
Externí odkaz:
https://doaj.org/article/44afd9d89a0f46408c84d103208d1566