Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Leilei, Fu"'
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-42 (2024)
Abstract The Phosphatidylinositol-3-kinase (PI3K) family is well-known to comprise three classes of intracellular enzymes. Class I PI3Ks primarily function in signaling by responding to cell surface receptor stimulation, while class II and III are mo
Externí odkaz:
https://doaj.org/article/e770822f68524248951df177dbe509f1
Autor:
Fu Peng, Minru Liao, Wenke Jin, Wei Liu, Zixiang Li, Zhichao Fan, Ling Zou, Siwei Chen, Lingjuan Zhu, Qian Zhao, Gu Zhan, Liang Ouyang, Cheng Peng, Bo Han, Jin Zhang, Leilei Fu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract Sirtuin 3 (SIRT3) is well known as a conserved nicotinamide adenine dinucleotide+ (NAD+)-dependent deacetylase located in the mitochondria that may regulate oxidative stress, catabolism and ATP production. Accumulating evidence has recently
Externí odkaz:
https://doaj.org/article/0c9da444ccf442e3b3e6e2e182b75a0c
Autor:
Zixiang Li, Leilei Fu
Publikováno v:
BMJ Oncology, Vol 3, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/712e1a85280d401891aead0765ce00a8
Publikováno v:
Heliyon, Vol 9, Iss 7, Pp e17582- (2023)
Tumor-associated macrophage (TAM) affects the intrinsic properties of tumor cells and the tumor microenvironment (TME), which can stimulate tumor cell proliferation, migration, and genetic instability, and macrophage diversity includes the diversity
Externí odkaz:
https://doaj.org/article/6a48e40aee5743a2a09bc5379a92847f
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-66 (2022)
Abstract Regulated cell death (RCD), also well-known as programmed cell death (PCD), refers to the form of cell death that can be regulated by a variety of biomacromolecules, which is distinctive from accidental cell death (ACD). Accumulating evidenc
Externí odkaz:
https://doaj.org/article/1d86f272f227411babae838ca74383ef
Autor:
Yongqi Zhen, Zhaoxin Yuan, Jiahui Zhang, Yao Chen, Yuning Fu, Yi Liu, Leilei Fu, Lan Zhang, Xian-Li Zhou
Publikováno v:
Cell Death and Disease, Vol 13, Iss 4, Pp 1-14 (2022)
Externí odkaz:
https://doaj.org/article/2165f572fca34be8bbf6b4216be44586
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-6 (2022)
Abstract Hepatocellular carcinoma (HCC) is well-known to be a highly prevalent malignant tumor, but the treatment of this pathological state has been still challenging. Solamargine (SM), a traditional Chinese herb-derived compound, has been widely re
Externí odkaz:
https://doaj.org/article/bfb563af3ae84c938161ad0aa86438e4
Autor:
Leilei Fu, Wenke Jin, Jiahui Zhang, Lingjuan Zhu, Jia Lu, Yongqi Zhen, Lan Zhang, Liang Ouyang, Bo Liu, Haiyang Yu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 2, Pp 532-557 (2022)
Drug repurposing or repositioning has been well-known to refer to the therapeutic applications of a drug for another indication other than it was originally approved for. Repurposing non-oncology small-molecule drugs has been increasingly becoming an
Externí odkaz:
https://doaj.org/article/a0d1d39b63ae40929af3862c8cf6140c
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/be4a59d70c5546e993b5e58e0894cda1
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Autophagy, originally described as a mechanism for intracellular waste disposal and recovery, has been becoming a crucial biological process closely related to many types of human tumors, including breast cancer, osteosarcoma, glioma, etc., suggestin
Externí odkaz:
https://doaj.org/article/7b8d661b848943a3aa39c09a05e50c07