Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Leila Topal"'
Autor:
Aiman Saleh A. Mohammed, Gábor Mohácsi, Muhammad Naveed, János Prorok, Norbert Jost, László Virág, István Baczkó, Leila Topal, András Varró
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Recent experimental data shows that hesperetin, a citrus flavonoid, affects potassium channels and can prolong the QTc interval in humans. Therefore, in the present study we investigated the effects of hesperetin on various transmembrane ion
Externí odkaz:
https://doaj.org/article/0971414e7dfb44bd8eb3ed45002410cd
Autor:
Alexandra Polyák, Leila Topal, Noémi Zombori-Tóth, Noémi Tóth, János Prorok, Zsófia Kohajda, Szilvia Déri, Vivien Demeter-Haludka, Péter Hegyi, Viktória Venglovecz, Gergely Ágoston, Zoltán Husti, Péter Gazdag, Jozefina Szlovák, Tamás Árpádffy-Lovas, Muhammad Naveed, Annamária Sarusi, Norbert Jost, László Virág, Norbert Nagy, István Baczkó, Attila S Farkas, András Varró
Publikováno v:
eLife, Vol 12 (2023)
The health benefits of regular physical exercise are well known. Even so, there is increasing evidence that the exercise regimes of elite athletes can evoke cardiac arrhythmias including ventricular fibrillation and even sudden cardiac death (SCD). T
Externí odkaz:
https://doaj.org/article/02b3774e90e748519b88740b22b943d6
Autor:
Muhammad Naveed, Aiman Saleh A. Mohammed, Leila Topal, Zsigmond Máté Kovács, Csaba Dienes, József Ovári, Norbert Szentandrássy, János Magyar, Tamás Bányász, János Prorok, Norbert Jost, László Virág, István Baczkó, András Varró, Péter P. Nánási, Balázs Horváth
Publikováno v:
Biomedicines, Vol 11, Iss 9, p 2383 (2023)
The present study was designed to test the hypothesis that the selectivity of blocking the late Na+ current (INaL) over the peak Na+ current (INaP) is related to the fast offset kinetics of the Na+ channel inhibitor. Therefore, the effects of 1 µM G
Externí odkaz:
https://doaj.org/article/4d6e1b0b3ba44596a4eb96b73ed834ff
Autor:
Tamás Hézső, Muhammad Naveed, Csaba Dienes, Dénes Kiss, János Prorok, Tamás Árpádffy-Lovas, Richárd Varga, Erika Fujii, Tanju Mercan, Leila Topal, Kornél Kistamás, Norbert Szentandrássy, János Almássy, Norbert Jost, János Magyar, Tamás Bányász, István Baczkó, András Varró, Péter P. Nánási, László Virág, Balázs Horváth
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Enhancement of the late Na+ current (INaL) increases arrhythmia propensity in the heart, while suppression of the current is antiarrhythmic. GS967 is an agent considered as a selective blocker of INaL. In the present study, effects of GS967
Externí odkaz:
https://doaj.org/article/73d50e33846d4bc7818bb17c0e8b0687
Autor:
Dénes Kiss, Balázs Horváth, Tamás Hézső, Csaba Dienes, Zsigmond Kovács, Leila Topal, Norbert Szentandrássy, János Almássy, János Prorok, László Virág, Tamás Bányász, András Varró, Péter P. Nánási, János Magyar
Publikováno v:
Pharmaceuticals, Vol 14, Iss 11, p 1142 (2021)
Enhancement of the late sodium current (INaL) increases arrhythmia propensity in the heart, whereas suppression of the current is antiarrhythmic. In the present study, we investigated INaL in canine ventricular cardiomyocytes under action potential v
Externí odkaz:
https://doaj.org/article/cedd9842b323421d81788f7c883d48be
Autor:
Khadija Belasri, Leila Topal, Matthias Heydenreich, Andreas Koch, Erich Kleinpeter, Ferenc Fülöp, István Szatmári
Publikováno v:
Molecules, Vol 25, Iss 11, p 2524 (2020)
The synthesis of new phenanthr[9,10-e][1,3]oxazines was achieved by the direct coupling of 9-phenanthrol with cyclic imines in the modified aza-Friedel–Crafts reaction followed by the ring closure of the resulting bifunctional aminophenanthrols wit
Externí odkaz:
https://doaj.org/article/2be646d684e94b2da5b8d74648c3909e
Autor:
Leila Topal, Alexandra Polyák, Noémi Zombori-Tóth, Noémi Tóth, János Prorok, Zsófia Kohajda, Szilvia Déri, Vivien Demeter-Haludka, Péter Hegyi, Viktória Venglovecz, Gergely Ágoston, Zoltán Husti, Péter Gazdag, Jozefina Szlovák, Tamás Árpádffy-Lovas, Muhammad Naveed, Annamária Sarusi, Norbert Jost, László Virág, Norbert Nagy, István Baczkó, Attila S Farkas, András Varró
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3f0b4f27357d76c1997a2953ea150bd
https://doi.org/10.7554/elife.80710.sa2
https://doi.org/10.7554/elife.80710.sa2
Autor:
Zsófia Kohajda, László Virág, Tibor Hornyik, Zoltán Husti, Anita Sztojkov‐Ivanov, Norbert Nagy, András Horváth, Richárd Varga, János Prorok, Jozefina Szlovák, Noémi Tóth, Péter Gazdag, Leila Topal, Muhammad Naveed, Tamás Árpádffy‐Lovas, Bence Pászti, Tibor Magyar, István Koncz, Szilvia Déri, Vivien Demeter‐Haludka, Zoltán Aigner, Balázs Ördög, Márta Patfalusi, László Tálosi, László Tiszlavicz, Imre Földesi, Norbert Jost, István Baczkó, András Varró
Publikováno v:
British Journal of Pharmacology. 179:3382-3402
The aim of the present study was to study the antiarrhythmic effects and cellular mechanisms of desethylamiodarone (DEA), the main metabolite of amiodarone (AMIO), following acute and chronic 4-week oral treatments (25-50 mg·kgThe antiarrhythmic eff
Autor:
Leila Topal, Alexandra Polyák, Noémi Zombori-Tóth, Noémi Tóth, János Prorok, Zsófia Kohajda, Szilvia Déri, Vivien Demeter-Haludka, Péter Hegyi, Viktória Venglovecz, Gergely Ágoston, Zoltán Husti, Péter Gazdag, Jozefina Szlovák, Tamás Árpádffy-Lovas, Muhammad Naveed, Annamária Sarusi, Norbert Jost, László Virág, Norbert Nagy, István Baczkó, Attila S Farkas, András Varró
The health benefits of regular physical exercise are well known. Even so, there is increasing evidence that the exercise regimes of elite athletes can evoke cardiac arrhythmias including ventricular fibrillation and even sudden cardiac death (SCD). T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c255790eaa1719c571972b98177308cc
https://doi.org/10.1101/2022.07.13.499876
https://doi.org/10.1101/2022.07.13.499876
Autor:
Boglárka Csupor-Löffler, László Virág, János Prorok, András Varró, István Baczkó, Bence József Pászti, Péter Orvos, Dezső Csupor, Leila Topal, Ákos Bajtel, Norbert Jost, Muhammad Naveed, Tivadar Kiss
Publikováno v:
Archives of Toxicology
Cannabis use is associated with known cardiovascular side effects such as cardiac arrhythmias or even sudden cardiac death. The mechanisms behind these adverse effects are unknown. The aim of the present work was to study the cellular cardiac electro