Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Leila Sarih"'
Autor:
Michel Ventura, Sandrine Reigadas, Simon Litvak, Michel Castroviejo, Leila Sarih-Cottin, Thérèse Astier-Gin
Publikováno v:
European Journal of Biochemistry. 268:5857-5867
The NS5B protein, or RNA-dependent RNA polymerase of the hepatitis virus type C, catalyzes the replication of the viral genomic RNA. Little is known about the recognition domains of the viral genome by the NS5B. To better understand the initiation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::111a023487794a0fa6bc2cc0b2698878
https://doi.org/10.1046/j.0014-2956.2001.02532.x
https://doi.org/10.1046/j.0014-2956.2001.02532.x
Publikováno v:
The FASEB Journal. 8:497-503
The human immunodeficiency virus type 1 (HIV-1) is the etiologic agent of AIDS. Replication of this virus requires the activity of a retrovirus encoded RNA-dependent DNA polymerase, or reverse transcriptase (RT). HIV-1 RT is required for the synthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7154be8b17fdbd53d039f135edf3b624
https://doi.org/10.1096/fasebj.8.8.7514143
https://doi.org/10.1096/fasebj.8.8.7514143
Autor:
Marie-Line Andreola, Leila Sarih-Cottin, Bruno Bordier, P J Barr, Laura Tarrago-Litvak, Michel Fournier, G A Nevinsky, Simon Litvak
Publikováno v:
Journal of Biological Chemistry. 267:19356-19362
The precursor homodimeric p66/p66 form of human immunodeficiency virus type-1 reverse transcriptase (HIV-1 RT) possesses the DNA polymerase and RNase H activities involved in the synthesis of the double-stranded provirus DNA. Reverse transcription is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce23f3d63e6cfcec6de6fa9ca4cf70f
https://doi.org/10.1016/s0021-9258(18)41782-6
https://doi.org/10.1016/s0021-9258(18)41782-6
Autor:
Philip J. Barr, Marie-Line Andreola, Karin Musier-Forsyth, Leila Sarih-Cottin, Simon Litvak, Bruno Bordier
Publikováno v:
Journal of Molecular Biology. 226:1-6
Primer tRNA regions involved in the interactions between human immunodeficiency virus reverse transcriptase (HIV RT) and tRNA Lys were studied by digestion of primer with pancreatic ribonuclease in the presence or absence of HIV RT. The acceptor stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d0d3bdb7a4ee0e55373af2012e7aa50
https://doi.org/10.1016/0022-2836(92)90117-3
https://doi.org/10.1016/0022-2836(92)90117-3
Publikováno v:
Nucleic Acids Research. 20:5999-6006
The molecular events involved in antisense-mediated inhibition of retroviral transcription were studied by analyzing the in vitro effect of antisense oligodeoxynucleotides on reverse transcription by Human Immunodeficiency Virus type 1 (HIV-1) revers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fce192e312c0cea0e65ee187a82dcef0
https://doi.org/10.1093/nar/20.22.5999
https://doi.org/10.1093/nar/20.22.5999
Autor:
Laura Tarrago-Litvak, Michel Fournier, Philip J. Barr, Danièle Tharaud, Marie-Line Sallafranque-Andreola, Leila Sarih-Cottin, Dominique Robert, Bruno Bordier, Simon Litvak
Publikováno v:
Nucleic Acids Research. 18:429-436
Human immunodeficiency virus (HIV) reverse transcriptase (RT) uses host tRNA(Lys) partially annealed to the primer binding site (PBS) as primer for the initiation of cDNA synthesis. When assaying cDNA synthesis with a template-primer complex formed b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38653b385d2ec61897cdcf4343963605
https://doi.org/10.1093/nar/18.3.429
https://doi.org/10.1093/nar/18.3.429
Publikováno v:
Biochimica et biophysica acta. 1351(3)
Antisense oligonucleotides (ODNs) overlapping the stem-loop structure of the trans-activating responsive (TAR) element at the 5' end of HIV-1 and HIV-2 viral RNAs were tested for their inhibitory effect on cDNA synthesis by HIV-1 and HIV-2 reverse tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7aa6493ddb4aa4cf3da8299c3a19c54
https://pubmed.ncbi.nlm.nih.gov/9130587
https://pubmed.ncbi.nlm.nih.gov/9130587
Autor:
Claude Hélène, Genevieve Degols, Simon Litvak, Maritta Perala-Heape, Bernard Lebleu, Leila Sarih-Cottin, Bruno Bordier
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 92(20)
We have investigated two regions of the viral RNA of human immunodeficiency virus type 1 (HIV-1) as potential targets for antisense oligonucleotides. An oligodeoxynucleotide targeted to the U5 region of the viral genome was shown to block the elongat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7146dbe136712d66b71c799f6513efe
https://pubmed.ncbi.nlm.nih.gov/7568137
https://pubmed.ncbi.nlm.nih.gov/7568137
Publikováno v:
Trends in biochemical sciences. 19(3)
The fundamental role played by reverse transcriptase in the replication of retroviruses has stimulated the study of the mechanism of action of this enzyme. The reverse transcriptase of the type 1 human immunodeficiency virus forms a stable complex wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803c9442ce665e3f186b973fc7521fab
https://pubmed.ncbi.nlm.nih.gov/7515521
https://pubmed.ncbi.nlm.nih.gov/7515521
Autor:
Leila Sarih, Thérèse Heyman, Bernadette Agoutin, Dominique Weill, Odile Lecoq, Pierre Jullien
Publikováno v:
Virology. 145:171-175
The effect of formycin, an adenosine analog, on the growth of chick embryo fibroblasts and on Rous sarcoma virus (RSV) production was studied. An adverse effect on cell proliferation was observed in the presence of 10 microM formycin. Treatment with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60cf99fbfcf0491c79ea13d9e034acc0
https://doi.org/10.1016/0042-6822(85)90212-0
https://doi.org/10.1016/0042-6822(85)90212-0