Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Leila Rachid"'
Autor:
Angela J. T. Bosch, Theresa V. Rohm, Shefaa AlAsfoor, Andy J. Y. Low, Lena Keller, Zora Baumann, Neena Parayil, Marc Stawiski, Leila Rachid, Thomas Dervos, Sandra Mitrovic, Daniel T. Meier, Claudia Cavelti-Weder
Publikováno v:
Particle and Fibre Toxicology, Vol 20, Iss 1, Pp 1-15 (2023)
Abstract Background Air pollution has emerged as an unexpected risk factor for diabetes. However, the mechanism behind remains ill-defined. So far, the lung has been considered as the main target organ of air pollution. In contrast, the gut has recei
Externí odkaz:
https://doaj.org/article/69c058265092496881f3beb53d3725e0
Autor:
Daniel T. Meier, Leila Rachid, Sophia J. Wiedemann, Shuyang Traub, Kelly Trimigliozzi, Marc Stawiski, Loïc Sauteur, Denise V. Winter, Christelle Le Foll, Catherine Brégère, Raphael Guzman, Alex Odermatt, Marianne Böni-Schnetzler, Marc Y. Donath
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Defective insulin secretion is observed early in the development of diabetes. Here the authors report that β cell-specific deficiency of the insulin prohormone convertase 1/3 (PC1/3) leads not only to hyperglycemia, but also to hyperphagic obesity i
Externí odkaz:
https://doaj.org/article/c2d52d524de146cb95b1f820a6251d26
Autor:
Theresa V. Rohm, Lena Keller, Angela J. T. Bosch, Shefaa AlAsfoor, Zora Baumann, Amandine Thomas, Sophia J. Wiedemann, Laura Steiger, Elise Dalmas, Josua Wehner, Leila Rachid, Catherine Mooser, Bahtiyar Yilmaz, Nerea Fernandez Trigo, Annaise J. Jauch, Stephan Wueest, Daniel Konrad, Sandrine Henri, Jan H. Niess, Petr Hruz, Stephanie C. Ganal-Vonarburg, Julien Roux, Daniel T. Meier, Claudia Cavelti-Weder
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Expansion of pro-inflammatory macrophages in the colon occurs early after high-fat diet initiation, prior to macrophage accumulation in the adipose tissue, in a microbiome-dependent fashion. Macrophage depletion systemically and/or exclusively in the
Externí odkaz:
https://doaj.org/article/80b59b6deb3e496981cc210ada5bc2b9
Autor:
Marianne Böni-Schnetzler, Hélène Méreau, Leila Rachid, Sophia J. Wiedemann, Friederike Schulze, Kelly Trimigliozzi, Daniel T. Meier, Marc Y. Donath
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103250- (2021)
Summary: Aging is the prime risk factor for the development of type 2 diabetes. We investigated the role of the interleukin-1 (IL-1) system on insulin secretion in aged mice. During aging, expression of the protective IL-1 receptor antagonist decreas
Externí odkaz:
https://doaj.org/article/8c210037d7104ffebcadf66383ce7f6c
Autor:
Axel de Baat, Daniel T Meier, Leila Rachid, Adriano Fontana, Marianne Böni-Schnetzler, Marc Y Donath
System Xc-, encoded bySlc7a11, is an antiporter that exports glutamate and imports cystine. Cystine is used for protein synthesis and incorporation in thiol peptides such as glutathione, which function as cofactors for reactive oxygen species scaveng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce9c2a2ac7f823729ef01272a822b89a
https://doi.org/10.1101/2023.01.19.524735
https://doi.org/10.1101/2023.01.19.524735
Autor:
Erez Dror, Marc Y. Donath, Hélène Méreau, Friederike Schulze, Kelly Trimigliozzi, Stéphanie P. Häuselmann, Marianne Böni-Schnetzler, Daniel T. Meier, Marc Stawiski, Leila Rachid, Jose Alberto Molina-Tijeras, Sophia J. Wiedemann, Christelle Le Foll, Christophe Magnan
The initial cephalic phase of insulin secretion is mediated through the vagus nerve and is not due to glycemic stimulation of pancreatic β-cells. Recently, IL-1β was shown to stimulate postprandial insulin secretion. Here, we describe that this inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb406ec06f7a686f45298c77bee55f2
https://www.zora.uzh.ch/id/eprint/211022/
https://www.zora.uzh.ch/id/eprint/211022/
Autor:
Kelly Trimigliozzi, Marianne Boeni-Schnetzler, Daniel T. Meier, Erez Dror, Sophia J. Wiedemann, Theresa V. Rohm, Friederike Schulze, Jose Alberto Molina-Tijeras, Hélène Méreau, Marc Y. Donath, Leila Rachid, Christophe Magnan, Stéphanie P. Häuselmann
Publikováno v:
Diabetes. 69
The non-glucose dependent spike in insulin levels immediately following the beginning of a meal is called the cephalic or pre-absorptive phase of insulin secretion. Even though this early insulin response is of marked consequence for overall postpran
Autor:
Friederike, Schulze, Josua, Wehner, Denise V, Kratschmar, Valmir, Makshana, Daniel T, Meier, Stéphanie P, Häuselmann, Elise, Dalmas, Constanze, Thienel, Erez, Dror, Sophia J, Wiedemann, Shuyang, Traub, Thierry M, Nordmann, Leila, Rachid, Axel, De Baat, Theresa V, Rohm, Cheng, Zhao, Alex, Odermatt, Marianne, Böni-Schnetzler, Marc Y, Donath
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Gestational diabetes mellitus (GDM) is one of the most common diseases associated with pregnancy, however, the underlying mechanisms remain unclear. Based on the well documented role of inflammation in type 2 diabetes, the aim was to investigate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::976405532cde1a3d3d9ec6e2c0b3848a
Autor:
Marc Y. Donath, Friederike Schulze, Sophia J. Wiedemann, Kelly Trimigliozzi, Leila Rachid, Marianne Böni-Schnetzler, Hélène Méreau, Daniel T. Meier
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103250-(2021)
iScience
iScience
Summary Aging is the prime risk factor for the development of type 2 diabetes. We investigated the role of the interleukin-1 (IL-1) system on insulin secretion in aged mice. During aging, expression of the protective IL-1 receptor antagonist decrease
Autor:
Leila Rachid, Marianne Böni-Schnetzler, Sophia J. Wiedemann, Ben Min-Woo Illigens, Marc Y. Donath
Publikováno v:
Appetite. 155:104792
The initial release of insulin in response to food stimuli acting on receptors in the head and oropharynx is called the cephalic phase of insulin secretion. Insulin has been shown to act centrally to regulate food intake and glucose metabolism and th