Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Leila Muresan"'
Publikováno v:
Epigenetics & Chromatin, Vol 17, Iss 1, Pp 1-20 (2024)
Abstract Chromatin state is thought to impart regulatory function to the underlying DNA sequence. This can be established through histone modifications and chromatin organisation, but exactly how these factors relate to one another to regulate gene e
Externí odkaz:
https://doaj.org/article/8bee592146c54f82971e535ec2e354ff
Autor:
Yasmin Striedner, Barbara Arbeithuber, Sofia Moura, Elisabeth Nowak, Ronja Reinhardt, Leila Muresan, Renato Salazar, Thomas Ebner, Irene Tiemann-Boege
Publikováno v:
Genes, Vol 15, Iss 2, p 191 (2024)
Advanced paternal age increases the risk of transmitting de novo germline mutations, particularly missense mutations activating the receptor tyrosine kinase (RTK) signalling pathway, as exemplified by the FGFR3 mutation, which is linked to achondropl
Externí odkaz:
https://doaj.org/article/bfbb980d3f19486b9709390e035e5d77
Autor:
Madeleine L Ball, Stefan A Koestler, Leila Muresan, Sohaib Abdul Rehman, Kevin O'Holleran, Robert White
Publikováno v:
PLoS Genetics, Vol 19, Iss 3, p e1010654 (2023)
While the biochemistry of gene transcription has been well studied, our understanding of how this process is organised in 3D within the intact nucleus is less well understood. Here we investigate the structure of actively transcribed chromatin and th
Externí odkaz:
https://doaj.org/article/6a5838a75b8a428d956da8df6d3b3242
Autor:
Felicity M. Davis, Bethan Lloyd-Lewis, Olivia B. Harris, Sarah Kozar, Douglas J. Winton, Leila Muresan, Christine J. Watson
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
The identity and origin of adult mammary stem cells has been much debated. Here, the authors use a stochastic genetic labelling approach, together with optical tissue clearing, to visualize clonal progeny and show that unipotent stem/progenitor cells
Externí odkaz:
https://doaj.org/article/2948887d405f4119b2412369a6efdc95
Autor:
Claire M Lye, Guy B Blanchard, Huw W Naylor, Leila Muresan, Jan Huisken, Richard J Adams, Bénédicte Sanson
Publikováno v:
PLoS Biology, Vol 13, Iss 11, p e1002292 (2015)
How genetic programs generate cell-intrinsic forces to shape embryos is actively studied, but less so how tissue-scale physical forces impact morphogenesis. Here we address the role of the latter during axis extension, using Drosophila germband exten
Externí odkaz:
https://doaj.org/article/4cfecd594b4a45b98d4992c2fe8b1505
Autor:
Gaëlle Demarre, Elisa Galli, Leila Muresan, Evelyne Paly, Ariane David, Christophe Possoz, François-Xavier Barre
Publikováno v:
PLoS Genetics, Vol 10, Iss 9, p e1004557 (2014)
The replication terminus region (Ter) of the unique chromosome of most bacteria locates at mid-cell at the time of cell division. In several species, this localization participates in the necessary coordination between chromosome segregation and cell
Externí odkaz:
https://doaj.org/article/fc84e94f29984f6098026e6abd59133d
Autor:
Ariane David, Gaëlle Demarre, Leila Muresan, Evelyne Paly, François-Xavier Barre, Christophe Possoz
Publikováno v:
PLoS Genetics, Vol 10, Iss 7, p e1004448 (2014)
The segregation of bacterial chromosomes follows a precise choreography of spatial organisation. It is initiated by the bipolar migration of the sister copies of the replication origin (ori). Most bacterial chromosomes contain a partition system (Par
Externí odkaz:
https://doaj.org/article/39ef2cd2b65f43189d90d7380ca4ddd8
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e36064 (2012)
In spite of the many advances in haplotyping methods, it is still very difficult to characterize rare haplotypes in tissues and different environmental samples or to accurately assess the haplotype diversity in large mixtures. This would require a ha
Externí odkaz:
https://doaj.org/article/fd279eb2c962481c8378fdf442cf4230
Autor:
Linus Manubens-Gil, Zhi Zhou, Hanbo Chen, Arvind Ramanathan, Xiaoxiao Liu, Yufeng Liu, Alessandro Bria, Todd Gillette, Zongcai Ruan, Jian Yang, Miroslav Radojević, Ting Zhao, Li Cheng, Lei Qu, Siqi Liu, Kristofer E. Bouchard, Lin Gu, Weidong Cai, Shuiwang Ji, Badrinath Roysam, Ching-Wei Wang, Hongchuan Yu, Amos Sironi, Daniel Maxim Iascone, Jie Zhou, Erhan Bas, Eduardo Conde-Sousa, Paulo Aguiar, Xiang Li, Yujie Li, Sumit Nanda, Yuan Wang, Leila Muresan, Pascal Fua, Bing Ye, Hai-yan He, Jochen F. Staiger, Manuel Peter, Daniel N. Cox, Michel Simonneau, Marcel Oberlaender, Gregory Jefferis, Kei Ito, Paloma Gonzalez-Bellido, Jinhyun Kim, Edwin Rubel, Hollis T. Cline, Hongkui Zeng, Aljoscha Nern, Ann-Shyn Chiang, Jianhua Yao, Jane Roskams, Rick Livesey, Janine Stevens, Tianming Liu, Chinh Dang, Yike Guo, Ning Zhong, Georgia Tourassi, Sean Hill, Michael Hawrylycz, Christof Koch, Erik Meijering, Giorgio A. Ascoli, Hanchuan Peng
Publikováno v:
Nature Methods
BigNeuron is an open community bench-testing platform with the goal of setting open standards for accurate and fast automatic neuron tracing. We gathered a diverse set of image volumes across several species that is representative of the data obtaine