Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Leila Issmail"'
Autor:
Jannik T. Wagner, Sandra M. Müller-Schmucker, Wenjun Wang, Philipp Arnold, Nadja Uhlig, Leila Issmail, Valentina Eberlein, Dominik Damm, Kaveh Roshanbinfar, Armin Ensser, Friederike Oltmanns, Antonia Sophia Peter, Vladimir Temchura, Silke Schrödel, Felix B. Engel, Christian Thirion, Thomas Grunwald, Manfred Wuhrer, Dirk Grimm, Klaus Überla
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract Long-acting passive immunization strategies are needed to protect immunosuppressed vulnerable groups from infectious diseases. To further explore this concept for COVID-19, we constructed Adeno-associated viral (AAV) vectors encoding the hum
Externí odkaz:
https://doaj.org/article/fb0eb88696d04de18d534ac0c445bf7a
Autor:
Rebecca Weiß, Leila Issmail, Alexandra Rockstroh, Thomas Grunwald, Jasmin Fertey, Sebastian Ulbert
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionWest Nile Virus (WNV) is a zoonotic flavivirus transmitted by mosquitoes. Especially in the elderly or in immunocompromised individuals an infection with WNV can lead to severe neurological symptoms. To date, no human vaccine against WNV
Externí odkaz:
https://doaj.org/article/970780d95e914b9fb14d4644f321fbfe
Autor:
Dennis Lapuente, Jana Fuchs, Jonas Willar, Ana Vieira Antão, Valentina Eberlein, Nadja Uhlig, Leila Issmail, Anna Schmidt, Friederike Oltmanns, Antonia Sophia Peter, Sandra Mueller-Schmucker, Pascal Irrgang, Kirsten Fraedrich, Andrea Cara, Markus Hoffmann, Stefan Pöhlmann, Armin Ensser, Cordula Pertl, Torsten Willert, Christian Thirion, Thomas Grunwald, Klaus Überla, Matthias Tenbusch
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
While current COVID-19 vaccines provide certain protection, more effective vaccination strategies are still desirable. Here the authors show, using mouse vaccination models, that priming with a systemic mRNA and boosting with an intranasal adenoviral
Externí odkaz:
https://doaj.org/article/2d658f5bfe1141c4acf2fa4bf72300b6
Autor:
Leila Issmail, Christin Möser, Christian Jäger, Basma Altattan, Daniel Ramsbeck, Martin Kleinschmidt, Mirko Buchholz, David Smith, Thomas Grunwald
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
Human respiratory syncytial virus (RSV) is the primary cause of acute lower respiratory tract infections in children and the elderly worldwide, for which neither a vaccine nor an effective therapy is approved. The entry of RSV into the host cell is m
Externí odkaz:
https://doaj.org/article/e691e42ef8224ec587f1da3b430fc2ac
Autor:
Rüdiger Groß, Lívia Mesquita Dias Loiola, Leila Issmail, Nadja Uhlig, Valentina Eberlein, Carina Conzelmann, Lia‐Raluca Olari, Lena Rauch, Jan Lawrenz, Tatjana Weil, Janis A. Müller, Mateus Borba Cardoso, Andrea Gilg, Olivia Larsson, Urban Höglund, Sandra Axberg Pålsson, Anna Selch Tvilum, Kaja Borup Løvschall, Maria M. Kristensen, Anna‐Lena Spetz, Fortune Hontonnou, Marie Galloux, Thomas Grunwald, Alexander N. Zelikin, Jan Münch
Publikováno v:
Advanced Science, Vol 9, Iss 20, Pp n/a-n/a (2022)
Abstract Inhibitors of viral cell entry based on poly(styrene sulfonate) and its core–shell nanoformulations based on gold nanoparticles are investigated against a panel of viruses, including clinical isolates of SARS‐CoV‐2. Macromolecular inhi
Externí odkaz:
https://doaj.org/article/efb36e92da2449a5bac3fba657c93ca6
Autor:
Kim M. Stegmann, Antje Dickmanns, Natalie Heinen, Claudia Blaurock, Tim Karrasch, Angele Breithaupt, Robert Klopfleisch, Nadja Uhlig, Valentina Eberlein, Leila Issmail, Simon T. Herrmann, Amelie Schreieck, Evelyn Peelen, Hella Kohlhof, Balal Sadeghi, Alexander Riek, John R. Speakman, Uwe Groß, Dirk Görlich, Daniel Vitt, Thorsten Müller, Thomas Grunwald, Stephanie Pfaender, Anne Balkema-Buschmann, Matthias Dobbelstein
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104293- (2022)
Summary: The nucleoside analog N4-hydroxycytidine (NHC) is the active metabolite of the prodrug molnupiravir, which has been approved for the treatment of COVID-19. SARS-CoV-2 incorporates NHC into its RNA, resulting in defective virus genomes. Likew
Externí odkaz:
https://doaj.org/article/3893fdc86a5b4569a07925c5deb2bfb2
Autor:
Julia Finkensieper, Leila Issmail, Jasmin Fertey, Alexandra Rockstroh, Simone Schopf, Bastian Standfest, Martin Thoma, Thomas Grunwald, Sebastian Ulbert
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tick-borne encephalitis virus (TBEV) is a zoonotic flavivirus which is endemic in many European and Asian countries. Humans can get infected with TBEV usually via ticks, and possible symptoms of the infection range from fever to severe neurological c
Externí odkaz:
https://doaj.org/article/509a87780bb64765ba419b62d3353b44
Autor:
Jasmin Fertey, Martin Thoma, Jana Beckmann, Lea Bayer, Julia Finkensieper, Susann Reißhauer, Beatrice Sarah Berneck, Leila Issmail, Jessy Schönfelder, Javier Portillo Casado, Andre Poremba, Frank-Holm Rögner, Bastian Standfest, Gustavo R. Makert, Lia Walcher, Ann-Kathrin Kistenmacher, Stephan Fricke, Thomas Grunwald, Sebastian Ulbert
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/25c560b0f170497ebd0173e7c2f587a8
Autor:
Sarah Wilmschen, Sabrina Schneider, Felix Peters, Lea Bayer, Leila Issmail, Zoltán Bánki, Thomas Grunwald, Dorothee von Laer, Janine Kimpel
Publikováno v:
Vaccines, Vol 7, Iss 3, p 59 (2019)
The respiratory syncytial virus (RSV) is one major cause of lower respiratory tract infections in childhood and an effective vaccine is still not available. We previously described a new rhabdoviral vector vaccine, VSV-GP, a variant of the vesicular
Externí odkaz:
https://doaj.org/article/2b09f71496554d7da6d241eb92992fef
Autor:
Markus Hoffmann, Sandra Ciesek, Dirk Mielenz, Leila Issmail, Sebastian R. Schulz, Eileen Socher, Eva Grüner, Katharina Habenicht, Roman Wölfel, Paul F. McKay, Hans-Martin Jäck, Tobit Steinmetz, Robin J. Shattock, Ralf Wagner, Valentina Eberlein, Edith Roth, Heinrich Sticht, Jutta Eichler, Stefan Pöhlmann, Matthias Tenbusch, Frank Neipel, Wolfgang Schuh, Elie Richel, Kirsten Fraedrich, Thomas Winkler, Thomas Grunwald, Sandra Mueller-Schmucker, Antonia Sophia Peter, Simon Dolles, Klaus Überla, Nadja Uhlig, Armin Ensser, David Peterhoff, Dominik Damm, Manuela Hauke
Publikováno v:
European Journal of Immunology
TRIANNI mice carry an entire set of human immunoglobulin V region gene segments and are a powerful tool to rapidly isolate human monoclonal antibodies. After immunizing these mice with DNA encoding the spike protein of SARS‐CoV‐2 and boosting wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb13b928f02eaac23f497c4789f9a82
https://publica.fraunhofer.de/handle/publica/270534
https://publica.fraunhofer.de/handle/publica/270534