Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Leila Bou-Salah"'
Autor:
Abderahmane Linani, Sabrina Bensenouci, Ben lahbib Hafsa, Khedidja Benarous, Talia Serseg, Leila Bou-Salah, Bader Y. Alhatlani
Publikováno v:
Applied Sciences, Vol 14, Iss 20, p 9306 (2024)
This study investigated the potential of five pyrrole-imidazole alkaloids from the marine sponge Agelas sp. to inhibit key targets in neuroblastoma, the most common pediatric malignant solid tumor. Molecular docking analysis using GOLD software (v4.1
Externí odkaz:
https://doaj.org/article/35cbdf16b2fa4b57a3b96f5225bbaecb
Publikováno v:
Chemico-biological interactions. 359
Over-consumption of foods high in purines like seafood, red meat, and alcoholic beverages leads to hyperuricemia causing gout attacks. Xanthine oxidase was reported responsible for the overproduction of uric acid.We intend to test in silico and in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d68542dd8ba44eb47b4c374748df8a98
https://pubmed.ncbi.nlm.nih.gov/35395231
https://pubmed.ncbi.nlm.nih.gov/35395231
Autor:
Kheira Chaib, Leila Bou-Salah, Abderahmane Linani, Mohamed Yousfi, Khedidja Benarous, Imane Chine, Hadjer Bensaidane, Faiza Rabhi
Publikováno v:
Molecular and cellular probes. 58
The two important targets to treat gout disease are (1) control the hyperuricemia by the inhibition of Xanthine Oxidase (XO) and (2) treatment of acute attacks of gout by the use of anti-inflammatory drugs. It is important to distinguish between ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d76d47e2f754862e7845fd07fef939
https://pubmed.ncbi.nlm.nih.gov/33957269
https://pubmed.ncbi.nlm.nih.gov/33957269
Autor:
Leila Bou-Salah, Mohamed Yousfi, Abderrahmane Linani, Khedidja Benarous, Luciano Saso, Irena Kostova
Publikováno v:
Journal of biomolecular structuredynamics. 40(6)
The gout disease is spreading worldwide and its drug target is the human xanthine oxidase. Through this work, we investigated the inhibitory effect of the ten lanthanide(III) complexes of biologically active bis-coumarins on xanthine oxidase. We achi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::317f5b7a8a20a07f2a6d003de18f7e16
https://pubmed.ncbi.nlm.nih.gov/33146077
https://pubmed.ncbi.nlm.nih.gov/33146077
Publikováno v:
Bioorganic Chemistry. 112:104937
Alkaloids and phenols are potent inhibitors family for many enzymes used in many therapies. We aim to evaluate in vitro and in silico, the inhibition effect of Hispidin, Harmaline, and Harmine as pure molecules to bovine milk xanthine oxidase (BXO),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d120f21093a827668e5e33fa628a7f46
https://doi.org/10.1016/j.bioorg.2021.104937
https://doi.org/10.1016/j.bioorg.2021.104937