Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Leila Barghi"'
Autor:
Leila Barghi
Publikováno v:
مجله علمی دانشگاه علوم پزشکی کردستان, Vol 28, Iss 5, Pp 122-130 (2023)
Background and Aim: Recently, nanostructured drug delivery systems have been investigated as delivery systems for chemotherapeutic agents in cancer treatment. The aim of this study was to review nanostructured carriers for targeted drug delivery of c
Externí odkaz:
https://doaj.org/article/d3439546a2e54258b25871267d0c585a
Publikováno v:
Journal of Research in Applied and Basic Medical Sciences, Vol 8, Iss 2, Pp 69-74 (2022)
Background & Aims: One of the significant steps in the preformulation of pharmaceutical dosage forms is to examine active pharmaceutical ingredient (API) compatibility with the excipients applied with it. Drug-excipient incompatibility affects the st
Externí odkaz:
https://doaj.org/article/73bebc5add844b3d83b3ac0f344d0424
Publikováno v:
Advances in Pharmacological and Pharmaceutical Sciences, Vol 2023 (2023)
Introduction. Limited aqueous solubility and subsequent poor absorption and low bioavailability are the main challenges in oral drug delivery. Solid dispersion is a widely used formulation strategy to overcome this problem. Despite their efficiency,
Externí odkaz:
https://doaj.org/article/9cc0f526ee4c48b1bf1ff44667f489ee
Autor:
Zahra Moradpour, Leila Barghi
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 22, Iss 1 (2019)
Epidermal growth factor receptors (EGFRs) have potential to be considered as therapeutic target for cancer treatment especially in cancer patients with overexpression of EGFR. Cetuximab as a first monoclonal antibody and Imatinib as the first small m
Externí odkaz:
https://doaj.org/article/fb1e474dee4348d2820a678706edfc4e
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 5, Iss 1, Pp 51-56 (2015)
Purpose: Polycaprolactone (PCL) is a biodegradable polyester and has attracted attention as a suitable carrier for development of controlled drug delivery due to its non-toxicity and biocompatibility. It has been reported that the biodegradability of
Externí odkaz:
https://doaj.org/article/9526f630e90c4e20a49563d72a0dd2ad
Publikováno v:
Biology Methods & Protocols
Erlotinib hydrochloride, a selective tyrosine kinase inhibitor approved for treatment of non-small cell lung cancer firstly. Erlotinib classified as class II drugs in the Biopharmaceutical Classification System (BCS), which characterized by low solub
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 2, Iss 1, Pp 119-122 (2012)
Purpose: An improved and economical method has been described for the synthesis of erlotinib hydrochloride, as a useful drug in treatment of non-small-cell lung cancer. Methods: Erlotinib hydrochloride was synthesized in seven steps starting from 3,
Externí odkaz:
https://doaj.org/article/b554069160754acb9ece3ee9f57bee47
Autor:
Maryam Maghsoodi, Leila Barghi
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 1, Iss 1, Pp 27-33 (2011)
Introduction: The percolation theory studies the critical points or percolation thresholds of the system, where onecomponent of the system undergoes a geometrical phase transition, starting to connect the whole system. The application of this theory
Externí odkaz:
https://doaj.org/article/39aab2ea3f724b948f347a2b423eee31
Autor:
Maryam Maghsoodi, Leila Barghi
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 14, Iss 48 (2011)
Objective(s)Ibuprofen is a problematic drug in tableting, and dissolution due to its poor solubility, hydrophobicity, and tendency to stick to surface. Because of the bad compaction behavior ibuprofen has to be granulated usually before tableting. Ho
Externí odkaz:
https://doaj.org/article/2e95d7dabb554cddb5c839088a8b1d9f
Publikováno v:
Asian Pacific Journal of Cancer Prevention. 15:10281-10287
Background: Development of a nanosized polymeric delivery system for erlotinib was the main objective of this research. Materials and Methods: Poly caprolactone-polyethylene glycol-polycaprolactone (PCEC) copolymers with different compositions were s