Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Leila, Rochin"'
Autor:
Maria Livia Sassano, Alexander R. van Vliet, Ellen Vervoort, Sofie Van Eygen, Chris Van den Haute, Benjamin Pavie, Joris Roels, Johannes V. Swinnen, Marco Spinazzi, Leen Moens, Kristina Casteels, Isabelle Meyts, Paolo Pinton, Saverio Marchi, Leila Rochin, Francesca Giordano, Blanca Felipe-Abrio, Patrizia Agostinis
Publikováno v:
Journal of Cell Biology. 222
The integrity of ER-mitochondria appositions ensures transfer of ions and phospholipids (PLs) between these organelles and exerts crucial effects on mitochondrial bioenergetics. Malfunctions within the ER-mitochondria contacts altering lipid traffick
Autor:
David Tareste, Vera F Monteiro-Cardoso, Francesca Giordano, Audrey Houcine, Annukka M. Kivelä, Eyra Marien, Romain Le Bars, Naima El Khallouki, Elena Santonico, Eeva Jääskeläinen, Leila Rochin, Vesa M. Olkkonen, Johannes V. Swinnen, Jonas Dehairs, Amita Arora, Julie Neveu, Cécile Sauvanet
Publikováno v:
Cell reports. 40(12)
Mitochondria are dynamic organelles essential for cell survival whose structural and functional integrity rely on selective and regulated transport of lipids from/to the endoplasmic reticulum (ER) and across the mitochondrial intermembrane space. As
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 9, p 1438 (2016)
In pigment cells, melanin synthesis takes place in specialized organelles, called melanosomes. The biogenesis and maturation of melanosomes is initiated by an unpigmented step that takes place prior to the initiation of melanin synthesis and leads to
Externí odkaz:
https://doaj.org/article/fef7aa4b825c43459ad82097c123a6fe
Autor:
David Tareste, Xingjie Ma, Johannes V. Swinnen, Annukka M. Kivelä, Julie Neveu, Cécile Sauvanet, David Bernard, Audrey Houcine, Romain Le Bars, Jonas Dehairs, Francesca Giordano, Vesa M. Olkkonen, Eeva Jääskeläinen, Eyra Marien, Leila Rochin
Publikováno v:
BioRxiv
BioRxiv, 2020, pp.695577. ⟨10.1101/695577⟩
BioRxiv, 2020, pp.695577. ⟨10.1101/695577⟩
Publisher: Cold Spring Harbor Laboratory Section: New Results; \textlessh3\textgreaterABSTRACT\textless/h3\textgreater \textlessp\textgreaterMitochondria are dynamic organelles essential for cell survival whose structural and functional integrity rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69903e5e2e372c659a4cbc68d8370921
https://hal.science/hal-03128735
https://hal.science/hal-03128735
Autor:
Ahmed Hamaï, Nivea Dias Amoedo, Francesca Giordano, Yang Sung Sohn, Peter Machin, Benoît de Chassey, Diana Molino, Patrice Codogno, Ola Karmi, Henri-Baptiste Marjault, Laetitia Lines, Irene Pila-Castellanos, Alessia Ruggieri, Damien Arnoult, Pauline Radreau, Rodrigue Rossignol, Etienne Morel, Eric Meldrum, Leila Rochin, Jacky Vonderscher, Rachel Nechushtai, Stéphane Joly, Katja Kopp
Publikováno v:
EMBO Rep
EMBO Reports
EMBO Reports, EMBO Press, 2020, 21 (12), ⟨10.15252/embr.201949019⟩
EMBO Reports, EMBO Press, 2020, ⟨10.15252/embr.201949019⟩
EMBO Reports
EMBO Reports, EMBO Press, 2020, 21 (12), ⟨10.15252/embr.201949019⟩
EMBO Reports, EMBO Press, 2020, ⟨10.15252/embr.201949019⟩
International audience; Several human pathologies including neurological, cardiac, infectious , cancerous, and metabolic diseases have been associated with altered mitochondria morphodynamics. Here, we identify a small organic molecule, which we name
Autor:
Leila Rochin, Michael J. Clague
Publikováno v:
Current Biology. 26:R332-R334
Recent large-scale proteomic analyses of two protein kinases that are linked to Parkinson's disease have identified a remarkable convergence between their respective impacts on the phosphoproteome: activation of both LRRK2 and PINK1 leads to phosphor
Autor:
Ragna, Sannerud, Cary, Esselens, Paulina, Ejsmont, Rafael, Mattera, Leila, Rochin, Arun Kumar, Tharkeshwar, Greet, De Baets, Veerle, De Wever, Roger, Habets, Veerle, Baert, Wendy, Vermeire, Christine, Michiels, Arjan J, Groot, Rosanne, Wouters, Katleen, Dillen, Katlijn, Vints, Pieter, Baatsen, Sebastian, Munck, Rita, Derua, Etienne, Waelkens, Guriqbal S, Basi, Mark, Mercken, Marc, Vooijs, Mathieu, Bollen, Joost, Schymkowitz, Frederic, Rousseau, Juan S, Bonifacino, Guillaume, Van Niel, Bart, De Strooper, Wim, Annaert
γ-Secretases are a family of intramembrane-cleaving proteases involved in various signaling pathways and diseases, including Alzheimer's disease (AD). Cells co-express differing γ-secretase complexes, including two homologous presenilins (PSENs). W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c5c028d17b3d033e77b773331674704a
https://lirias.kuleuven.be/handle/123456789/544673
https://lirias.kuleuven.be/handle/123456789/544673
Autor:
Graça Raposo, Maryse Romao, Michael S. Marks, Leila Rochin, Paul Saftig, Sabrina Simoes, Guillaume van Niel, Eric Rubinstein, Stéphanie Charrin
Publikováno v:
Developmental Cell. 21(4):708-721
Cargo sorting to intraluminal vesicles (ILVs) of multivesicular endosomes is required for numerous physiological processes including lysosome-related organelle (LRO) biogenesis. PMEL – a component of melanocyte LROs (melanosomes) – is sorted to I
Autor:
Michael S. Marks, Guillaume van Niel, Ilse Hurbain, Bart De Strooper, Leila Rochin, Cecile Fort, Graça Raposo, Brenda Watt, Pascal Leblanc, Lutgarde Serneels
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2013, 110 (26), pp.10658-10663. ⟨10.1073/pnas.1220748110⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2013, 110 (26), pp.10658-10663. ⟨10.1073/pnas.1220748110⟩
Amyloids are often associated with pathologic processes such as in Alzheimer’s disease (AD), but can also underlie physiological processes such as pigmentation. Formation of pathological and functional amyloidogenic substrates can require precursor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2968026497eb4de7c1830e27d133da9
https://europepmc.org/articles/PMC3696817/
https://europepmc.org/articles/PMC3696817/