Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Leila, Chaouch"'
Autor:
Mouna, Jaouani, Nadia, Hamdi, Leila, Chaouch, Miniar, Kalai, Fethi, Mellouli, Imen, Darragi, Imen, Boudriga, Dorra, Chaouachi, Mohamed, Bejaoui, Salem, Abbes
Publikováno v:
In Egyptian Journal of Medical Human Genetics July 2016 17(3):265-270
Autor:
Leila Chaouch, Miniar Kalai, Manel Ben Jbara, Arij Ben Chaabene, Imen Darragi, Dorra Chaouachi, Fethi Mallouli, Raouf Hafsia, Abderraouf Ghanem, Salem Abbes
Publikováno v:
Biomedical Papers, Vol 159, Iss 1, Pp 145-149 (2015)
Aims: The skeletal manifestations of sickle cell disease are the result of changes in bone and bone marrow caused by chronic tissue hypoxia that is exacerbated by episodic occlusion of the microcirculation by the abnormal sickle cells. Furthermore, t
Externí odkaz:
https://doaj.org/article/ff6c76f4151f4f91bc425bf5c7cf1453
Autor:
Houssem Sellami, Imen Darragi, Samia Mnif, Dorra Chaouachi, Leila Chaouch, Miniar Kalai, Imen Boudrigua, Salem Abbes
Publikováno v:
Journal of pediatric hematology/oncology. 42(1)
OBJECTIVES The 5' upstream region of the HBG1 gene plays a very important role in the expression of fetal hemoglobin (HbF). In contrast, increased HbF levels can inhibit the deoxygenation-induced polymerization of sickle hemoglobin (α2βS2), which l
Autor:
Emna Barkaoui, Imen Boudrigua, Faten Haddad, Nawel Trabelsi, Samia Menif, Salem Abbes, Dorra Chaouachi, Imen Darragi, Leila Chaouch, Mouna Jaouani
Publikováno v:
European Journal of Medical Genetics. 64:104139
Introduction Unconjugated hyperbilirubinemia (UCB) is a feature of Gilbert's syndrome (GS) and Crigler-Najjar's syndrome (CNS), which are two hereditary defects in bilirubin metabolism. Both syndromes are linked to mutations in the UGT1A1 gene, which
Autor:
Imen Darragi, Salem Abbes, Imen Boudrigua, Miniar Kalai, Houyem Ouragini, Mouna Ben Sassi, Raouf Hafsia, Leila Chaouch, Imen Moumni, Dorra Chaouachi
Publikováno v:
Acta Haematologica Polonica. 47:242-247
Background and aim Sickle cell anemia (SCA) is characterized by variable patterns of clinical expression. Polymorphisms linked to different genes have been associated with specific complications of the disease. Herein, we focused on the study of the
Autor:
Leila Chaouch, Fayza Ayari, Dorra Ben Guezella, Hayet Douik, Latifa Harzallah, Tasnim Mamoghli, Fethi Guemira, Arij Ben Chaaben, Hajer Abaza, Rachida Mejri, Nesrine Ouni
Publikováno v:
Bulletin du Cancer. 102:967-972
Cytochrome P450 2E1 (CYP2E1) is a detoxifying enzyme that belongs to the phase I metabolism of xenobiotics. This enzyme is encoded by a highly polymorphic gene whose common polymorphism corresponds to the substitution of cytosine (C) and thymine (T)
Autor:
Raouf Hafsia, Meriem Oueslati, Salem Abbes, Nawel Trabelsi, Wijdene Elborgi, Dorra Chaouachi, Imen Boudriga, Faten Haddad, Imen Darragi, Leila Chaouch, Houyem Ouragini
Publikováno v:
Hemoglobin. 41(2)
We report here the clinical, hematological and molecular data in a 50-year-old patient with β-thalassemia intermedia (β-TI) caused by a homozygous β+ mutation on the β-globin gene polyadenylation (polyA) signal (AATAAA>AAAAAA). β Haplotype analy
Autor:
Imen Moumni, Dorra Chaouachi, Imen Darragi, Marwa Dridi, Fethi Mellouli, Miniar Kalai, Salem Abbes, Mohamed Bejaoui, Leila Chaouch, Imen Boudrigua, Houyem Ouragini
Publikováno v:
Hematology (Amsterdam, Netherlands). 22(3)
Mediators of adhesion become a potential new target for pharmacological therapy to struggle the complications of sickle cell disease (SCD). Several mechanisms for increased adherence have been postulated and the well-studied are CD36 and VLA4 which e
Publikováno v:
Polish journal of pathology : official journal of the Polish Society of Pathologists
Polish journal of pathology : official journal of the Polish Society of Pathologists, 2013, 64 (2), pp.84-9. ⟨10.5114/PJP.2013.36012⟩
Polish journal of pathology : official journal of the Polish Society of Pathologists, 2013, 64 (2), pp.84-9. ⟨10.5114/PJP.2013.36012⟩
International audience; The pro-inflammatory context of sickle cell disease promotes the liberation of cytokines such as CCL5, encoded by a gene located on chromosome 17. Herein, the occurrence of three variations of CCL5 in sickle cell anemia (SCA)