Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Leihong, Xiang"'
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/287226132d5f49429a04e42a9297df64
Protease-Activated Receptor 2 in inflammatory skin disease: current evidence and future perspectives
Autor:
Mengjie Fan, Xiaoyao Fan, Yangfan Lai, Jin Chen, Yifan Peng, Yao Peng, Leihong Xiang, Ying Ma
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Protease-activated receptor-2 (PAR2) is a class-A G protein-coupled receptor (GPCR) activated by serine proteases and is expressed by multiple tissues, including the skin. PAR2 is involved in the skin inflammatory response, promoting Th2 inflammation
Externí odkaz:
https://doaj.org/article/672beeb21db547d9af4f10458ca45108
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Autophagy is a cellular process that functions to maintain intracellular homeostasis via the degradation and recycling of defective organelles or damaged proteins. This dynamic mechanism participates in various biological processes, such as the regul
Externí odkaz:
https://doaj.org/article/5a7d62d81fad4040981a87a346357b69
Publikováno v:
Journal of Dermatological Treatment, Vol 34, Iss 1 (2023)
AbstractInherited epidermolysis bullosa is a heterogeneous group of hereditary skin diseases characterized by skin (mucosa) fragility, which leads to blistering. Junctional epidermolysis bullosa is associated with mutations in genes expressing protei
Externí odkaz:
https://doaj.org/article/e7d4b6bfd7e14cd2b02f4a1b7c70fea8
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Fatty acid (FA) metabolism has been involved in acne vulgaris, a common inflammatory skin disease frequently observed in adolescents and adults, but it remains poorly defined whether the distributions or location of FA in facial sebum and those in th
Externí odkaz:
https://doaj.org/article/80c3ef46206943f485aca157c899cd10
Autor:
Juemin Zhao, Yanjun Dan, Ziqi Liu, Qianqian Wang, Min Jiang, Chengfeng Zhang, Hamm-Ming Sheu, Chrang-Shi Lin, Leihong Xiang
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Post-inflammatory hyperpigmentation (PIH) is a common acquired pigmentary disorder occurring after skin inflammation or injury. Ultraviolet B irradiation could exaggerate PIH clinically due to its effect on promoting cutaneous inflammation and melano
Externí odkaz:
https://doaj.org/article/611ab50eafae45c7906f61520c1dfa5a
Autor:
Xiaoxi Dai, Shanglin Jin, Yijie Xuan, Yiwen Yang, Xiaoli Lu, Chen Wang, Li Chen, Leihong Xiang, Chengfeng Zhang
Publikováno v:
Cells, Vol 11, Iss 24, p 3949 (2022)
Melasma is a common refractory acquired pigmentary skin disease that mainly affects middle-aged women. The pathogenesis of melasma is still uncertain, while abnormal vascular endothelial cells may play a role. We previously demonstrated the yellow li
Externí odkaz:
https://doaj.org/article/4badb8b2caef459184230a45154600be
Publikováno v:
Cells, Vol 11, Iss 7, p 1116 (2022)
Vitiligo is a common depigmented disease with unclear pathogenesis. Autophagy is crucial for maintaining cellular homeostasis and has been linked to a variety of autoimmune disorders; however, there have been no reports exploring the involvement of a
Externí odkaz:
https://doaj.org/article/6012c8e6d078474f9e755fd275ad867f
Publikováno v:
Experimental Dermatology. 31:633-640
BACKGROUND Oral tranexamic acid (TA) has been an effective treatment for melasma with unclear mechanism. OBJECTIVE The present study aimed to demonstrate the effect of TA on melanogenesis via regulation of TGF-β1 expression in keratinocytes. METHODS
Publikováno v:
Journal of Inflammation Research.
Ziqi Jiang,* Shanglin Jin,* Xiaoyao Fan, Ke Cao, Ye Liu, Xuan Wang, Ying Ma, Leihong Xiang Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, 200040, Peopleâs Republic of China*These authors contributed equally