Zobrazeno 1 - 10
of 768
pro vyhledávání: '"Leighton R"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Background: The Stroop task was used to investigate differences in cognitive function between Long COVID (LC), Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) and healthy control subjects. Methods: Subjects viewed four color wo
Externí odkaz:
https://doaj.org/article/628059e96e2c4ccf93c177ec277c4360
Autor:
Zack Y. Shan, Leighton R. Barnden, Richard A. Kwiatek, Sandeep Bhuta, Daniel F. Hermens, Jim Lagopoulos
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-11 (2020)
Abstract Background Since the 1990s, neuroimaging has been utilised to study Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), a debilitating illness with unknown aetiology. While brain abnormalities in ME/CFS have been identified, relativ
Externí odkaz:
https://doaj.org/article/77b3ff5d37b74d8da4b095c1d56c42e6
Publikováno v:
Open Access Rheumatology: Research and Reviews, Vol Volume 10, Pp 43-54 (2018)
Ross Leighton,1 Jane Fitzpatrick,2,3 Helen Smith,4 Daniela Crandall,4 Carl R Flannery,4 Thierry Conrozier5 1Department of Surgery, Dalhousie University, Halifax, NS, Canada; 2Sports Medicine Professionals Pty Ltd, Richmond, VIC, Australia; 3Universit
Externí odkaz:
https://doaj.org/article/082772b22e314cbbb4a0649eef15d4c8
Autor:
Leighton R. Barnden, Zack Y. Shan, Donald R. Staines, Sonya Marshall-Gradisnik, Kevin Finegan, Timothy Ireland, Sandeep Bhuta
Publikováno v:
NeuroImage: Clinical, Vol 20, Iss , Pp 102-109 (2018)
We recruited 43 Chronic Fatigue Syndrome (CFS) subjects who met Fukuda criteria and 27 healthy controls and performed 3T MRI T1 and T2 weighted spin-echo (T1wSE and T2wSE) scans. T1wSE signal follows T1 relaxation rate (1/T1 relaxation time) and resp
Externí odkaz:
https://doaj.org/article/60dba74b2c994b8080d0d8a46337d62c
Autor:
Zack Y. Shan, Kevin Finegan, Sandeep Bhuta, Timothy Ireland, Donald R. Staines, Sonya M. Marshall-Gradisnik, Leighton R. Barnden
Publikováno v:
NeuroImage: Clinical, Vol 19, Iss , Pp 279-286 (2018)
The mechanism underlying neurological dysfunction in chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is yet to be established. This study investigated the temporal complexity of blood oxygenation level dependent (BOLD) changes in response
Externí odkaz:
https://doaj.org/article/b0b914111e4f4917bd96d4fa3a895124
Autor:
Leighton R Barnden, Zack Y Shan, Donald R Staines, Sonya Marshall-Gradisnik, Kevin Finegan, Timothy Ireland, Sandeep Bhuta
Publikováno v:
NeuroImage: Clinical, Vol 24, Iss , Pp - (2019)
In myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS), abnormal MRI correlations with symptom severity and autonomic measures have suggested impaired nerve signal conduction within the brainstem. Here we analyse fMRI correlations to direc
Externí odkaz:
https://doaj.org/article/6185492eb71a4692a01abc27a3ea4b24
Publikováno v:
NeuroImage: Clinical, Vol 11, Iss C, Pp 530-537 (2016)
Autonomic changes are often associated with the chronic fatigue syndrome (CFS), but their pathogenetic role is unclear and brain imaging investigations are lacking. The vasomotor centre and, through it, nuclei in the midbrain and hypothalamus play a
Externí odkaz:
https://doaj.org/article/9275ff76d07846e9ba39bbf3e1ad3052
Autor:
Longquan Xu, Sylvia Hiller, Stephen Simington, Volker Nickeleit, Nobuyo Maeda, Leighton R James, Xianwen Yi
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0163208 (2016)
Oxidative stress is implicated in the pathogenesis of diabetic nephropathy (DN) but outcomes of many clinical trials are controversial. To define the role of antioxidants in kidney protection during the development of diabetic nephropathy, we have ge
Externí odkaz:
https://doaj.org/article/d87b69de10974cea84f68d7d2f71166d
Publikováno v:
Case Reports in Nephrology, Vol 2016 (2016)
Tuberous sclerosis complex is a rare multisystemic genetic disorder associated with the development of benign hamartomas. Angiomyolipomas are one such characteristic finding that may be seen in 55–80% of tuberous sclerosis complex patients. While b
Externí odkaz:
https://doaj.org/article/3b91cb2ea8884460970950ec42d5986e
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70441 (2013)
Connective tissue growth factor (CTGF) is an important mediator of fibrosis; emerging evidence link changes in plasma and urinary CTGF levels to diabetic kidney disease. To further ascertain the role of CTGF in responses to high glucose, we assessed
Externí odkaz:
https://doaj.org/article/98ba55e073c1460fb39afed91a64b641