Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Leighton G. Rodrigo"'
Autor:
Clare E. Gutteridge, Brett W. Sadowski, Stephen M. Hughes, J. Alan Friedlander, Alicia D. Gaidry, Michael C. Baxter, Matthew B. Smith, Leighton G. Rodrigo, Michael T. O'Neil, Lucia Gerena, Patricia J. Lee, Ramadas Sathunuru, Montip Gettayacamin
Publikováno v:
Medicinal chemistry (Shariqah (United Arab Emirates)).
Objective: A series of novel, substituted tetracyclic benzothiazepines were designed and prepared in an effort to optimize potency of this chemical class against drug-resistant strains of the malaria parasite. Method: Tetracyclic benzothiazepines bea
Autor:
J. Alan Friedlander, Brett W. Sadowski, Nathan C. Lorei, Michael C. Baxter, Stephen M. Hughes, Michael T. O’Neil, Leighton G. Rodrigo, Clare E. Gutteridge, Jonathan E. Harrell
Publikováno v:
International Journal of Organic Chemistry. 10:123-134
A versatile synthetic approach toward a series of benzothiazepines with medicinal potential (for example, compound 1) that allows incorporation of structural variation at the three aromatic regions of the structure, and at the sulfur atom, was develo