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of 12
pro vyhledávání: '"Leighcraft A, Shakes"'
Autor:
Delores J. Grant, Leighcraft A. Shakes, Hope M. Wolf, Derek C. Norford, Pradeep K. Chatterjee
Publikováno v:
AIMS Biophysics, Vol 2, Iss 4, Pp 773-793 (2015)
There is renewed interest in understanding expression of vertebrate genes in their chromosomal context because regulatory sequences that confer tissue-specific expression are often distributed over large distances along the DNA from the gene. One app
Externí odkaz:
https://doaj.org/article/552fd7c0cc3c426a98e4ef17514ac13a
Autor:
Pradeep K. Chatterjee, Delores J. Grant, Hope M. Wolf, Derek C. Norford, Leighcraft A. Shakes
Publikováno v:
AIMS Biophysics, Vol 2, Iss 4, Pp 773-793 (2015)
There is renewed interest in understanding expression of vertebrate genes in their chromosomal context because regulatory sequences that confer tissue-specific expression are often distributed over large distances along the DNA from the gene. One app
Autor:
Supriyo De, Tennison L. Malcolm, Pradeep K. Chatterjee, Ken R. Harewood, Kevin L. Allen, Leighcraft A. Shakes
Publikováno v:
Nucleic Acids Research
An enhancer within intron 1 of the amyloid precursor protein gene (APPb) of zebrafish is identified functionally using a novel approach. Bacterial artificial chromosomes (BACs) were retrofitted with enhancer traps, and expressed as transgenes in zebr
Autor:
Pradeep K, Chatterjee, Leighcraft A, Shakes, Hope M, Wolf, Mohammad A, Mujalled, Constance, Zhou, Charles, Hatcher, Derek C, Norford
Publikováno v:
RSC advances. 3(23)
Bacterial Artificial Chromosomes (BACs) are large pieces of DNA from the chromosomes of organisms propagated faithfully in bacteria as large extra-chromosomal plasmids. Expression of genes contained in BACs can be monitored after functionalizing the
Autor:
Katya K. De La Torre, Leighcraft A. Shakes, Kevin O. Nyabera, Derek C. Norford, Charles Hatcher, Mugtaba A Eltayeb, Hope M. Wolf, Pradeep K. Chatterjee
Publikováno v:
International Journal of Genomic Medicine.
Bacterial Artificial Chromosomes (BACs) are large extra-chromosomal plasmids in bacteria that faithfully propagate large pieces of DNA from the chromosomes of organisms. Because they represent tiny contiguous pieces of the chromosome, BACs are ideall
Autor:
Leighcraft A. Shakes, Derek C. Norford, Pradeep K. Chatterjee, Ranjan Sen, Hansen Du, Patricia Precht, Charles Hatcher, Hope M. Wolf
Publikováno v:
BMC Genomics, Vol 13, Iss 1, p 451 (2012)
BMC Genomics
BMC Genomics
Background Non-coding DNA in and around the human Amyloid Precursor Protein (APP) gene that is central to Alzheimer’s disease (AD) shares little sequence similarity with that of appb in zebrafish. Identifying DNA domains regulating expression of th
Autor:
Douglas M. Garland, Ken R. Harewood, Deepak Srivastava, Pradeep K. Chatterjee, Leighcraft A. Shakes
Publikováno v:
Nucleic Acids Research
Contrary to several earlier reports, we find that cross-recombination between wild-type and the mutant loxP511 sites is
Autor:
Ken R. Harewood, Douglas M. Garland, Kyle J. Moore, Deepak Srivastava, Leighcraft A. Shakes, Jonathon S. Coren, Pradeep K. Chatterjee
Publikováno v:
Nucleic acids research. 32(18)
Recombination of wild-type and mutant loxP sites mediated by wild-type Cre protein was analyzed in vivo using a sensitive phage P1 transduction assay. Contrary to some earlier reports, recombination between loxP sites was found to be highly specific:
Autor:
Ken R. Harewood, Goldie S. Byrd, Jonathon S. Coren, Sushmita Mukherjee, Pradeep K. Chatterjee, Leighcraft A. Shakes, Willie Wilson
Publikováno v:
Analytical biochemistry. 335(2)
New Tn10 minitransposons were constructed to functionally map long-range transcription regulatory sequences in bacterial artificial chromosomes (BACs) and P1-derived artificial chromosomes (PACs). Each contained a wild-type loxP site but, significant
Publikováno v:
Mobile Genetic Elements
Sequences that regulate expression of a gene in cis but are located at large distances along the DNA from the gene, as found with most developmentally regulated genes in higher vertebrates, are difficult to identify if those sequences are not conserv