Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Leigh-Anne D. Miller"'
Publikováno v:
Development. 136:2977-2985
The transcription factors Pax6 and Sox2 have been implicated in early events in lens induction and have been proposed to cooperate functionally. Here, we investigated the activity of Sox2 in lens induction and its genetic relationship to Pax6 in the
Autor:
April N. Smith, Leigh-Anne D. Miller, Judith A. West-Mays, Richard A. Lang, Giuseppe F. Pontoriero, Glenn L. Radice
Publikováno v:
Developmental Biology. 326:403-417
The classical cadherins are known to have both adhesive and signaling functions. It has also been proposed that localized regulation of cadherin activity may be important in cell assortment during development. In the context of eye development, it ha
Autor:
Susan E. Wert, Leigh-Anne D. Miller, Anne-Karina T. Perl, Yan Xu, Jeffrey A. Whitsett, Jean C. Clark
Publikováno v:
Developmental Dynamics. 231:57-71
Sonic hedgehog (Shh) was conditionally deleted in respiratory epithelial cells of the embryonic lung in vivo. Deletion of Shh before embryonic day (E) 13.5 resulted in respiratory failure at birth. While lobulation was not perturbed, the lungs were h
Publikováno v:
Journal of Histochemistry & Cytochemistry. 49:1593-1603
Expression of sonic hedgehog (Shh) is required for normal development of the lung during embryogenesis. Loss of Shh expression in mice results in tracheoesophageal fistula, lung hypoplasia, and abnormal lung lobulation. To determine whether Shh may p
Publikováno v:
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 129:141-149
The respiratory tract is lined by diverse epithelial cell types whose morphology, gene expression and functions are highly specialized along the cephalo-caudal axis of the lung. Pulmonary gas exchange, surface tension reduction, host defense, fluid a
Publikováno v:
Canadian Journal of Zoology. 77:902-909
Gap junctions are thought to play a role in pattern formation during limb development and regeneration by controlling the movement of small regulatory molecules between cells. An anteroposterior gradient of gap junctional communication that is higher
Publikováno v:
Canadian Journal of Zoology. 77:902-909
Publikováno v:
BMC Developmental Biology, Vol 6, Iss 1, p 14 (2006)
BMC Developmental Biology
BMC Developmental Biology
Background The canonical Wnt signaling pathway has a number of critical functions during embryonic development and, when activated aberrantly, in the genesis of cancer. Current evidence suggests that during eye development, regulation of Wnt signalin
Autor:
Leigh?Anne D. Miller, Susan E. Wert, Jean C. Clark, Yan Xu, Anne?Karina T. Perl, Jeffrey A. Whitsett
Publikováno v:
Developmental Dynamics; Sep2004, Vol. 231 Issue 1, p57-71, 15p
Autor:
Richard A. Lang, April N. Smith, Lee Niswander, Charlotte H. Dean, Daniel Dufort, Leigh-Anne D. Miller
Publikováno v:
Developmental Biology. (1):270-286
Key gene families such as FGFs and BMPs are important mediators of branching morphogenesis. To understand whether Wnt genes, and in particular, the canonical Wnt signaling pathway also function in the branching process, we have used a combination of