Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Leigh M Marsh"'
Autor:
Elisabeth Fließer, Anna Birnhuber, Leigh M Marsh, Elisabeth Gschwandtner, Walter Klepetko, Horst Olschewski, Grazyna Kwapiszewska
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 7, Iss 5, Pp 446-458 (2021)
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) poses a serious threat to healthcare systems worldwide. Binding of the virus to angiotensin‐converting enzyme 2 (ACE2) is an important step in the infection mechanism. Howeve
Externí odkaz:
https://doaj.org/article/f5f16b2ed5bc414591ae7c885504834b
Autor:
Mohammed Alrifai, Leigh M Marsh, Tanja Dicke, Ayse Kılıç, Melanie L Conrad, Harald Renz, Holger Garn
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85839 (2014)
BackgroundAllergic asthma is associated with chronic airway inflammation and progressive airway remodelling. However, the dynamics of the development of these features and their spontaneous and pharmacological reversibility are still poorly understoo
Externí odkaz:
https://doaj.org/article/a520367d8deb4954a0ff84bc9575161c
Autor:
Sarah Kretschmer, Ina Dethlefsen, Stefanie Hagner-Benes, Leigh M Marsh, Holger Garn, Peter König
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55201 (2013)
BackgroundLymphatic vessels play a pivotal role in fluid drainage and egress of immune cells from the lung. However, examining murine lung lymphatics is hampered by the expression of classical lymph endothelial markers on other cell types, which hind
Externí odkaz:
https://doaj.org/article/904f21eadd7b407c96d78151f5c75173
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55180 (2013)
Hypomorphic mutations in the bone morphogenic protein receptor (BMPR2) confer a much greater risk for developing pulmonary arterial hypertension (PAH). However, not all carriers of a mutation in the BMPR2 gene suffer from PAH. We have previously show
Externí odkaz:
https://doaj.org/article/791d6e3712bb4f769bd2d002eba47446
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 16 (2023)
The pulmonary vasculature has been frequently overlooked in acute and chronic lung diseases, such as acute respiratory distress syndrome (ARDS), pulmonary fibrosis (PF), and chronic obstructive pulmonary disease (COPD). The primary emphasis in the ma
Externí odkaz:
https://doaj.org/article/9f86419b4baa4a8a9a38e9a7a3558ac3
Autor:
Slaven Crnkovic, Francesco Valzano, Elisabeth Fließer, Jürgen Gindlhuber, Helene Thekkekara Puthenparampil, Maria Basil, Mike P. Morley, Jeremy Katzen, Elisabeth Gschwandtner, Walter Klepetko, Edward Cantu, Heimo Wolinski, Horst Olschewski, Jörg Lindenmann, You-Yang Zhao, Edward E. Morrisey, Leigh M. Marsh, Grazyna Kwapiszewska
Publikováno v:
JCI Insight, Vol 7, Iss 20 (2022)
A central feature of progressive vascular remodeling is altered smooth muscle cell (SMC) homeostasis; however, the understanding of how different cell populations contribute to this process is limited. Here, we utilized single-cell RNA sequencing to
Externí odkaz:
https://doaj.org/article/44b0a9ebfeff415b9c53d340fe872d68
Autor:
Martin Zacharias, Karl Kashofer, Philipp Wurm, Peter Regitnig, Moritz Schütte, Margit Neger, Sandra Ehmann, Leigh M. Marsh, Grazyna Kwapiszewska, Martina Loibner, Anna Birnhuber, Eva Leitner, Andrea Thüringer, Elke Winter, Stefan Sauer, Marion J. Pollheimer, Fotini R. Vagena, Carolin Lackner, Barbara Jelusic, Lesley Ogilvie, Marija Durdevic, Bernd Timmermann, Hans Lehrach, Kurt Zatloukal, Gregor Gorkiewicz
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104926- (2022)
Summary: Secondary infections contribute significantly to covid-19 mortality but driving factors remain poorly understood. Autopsies of 20 covid-19 cases and 14 controls from the first pandemic wave complemented with microbial cultivation and RNA-seq
Externí odkaz:
https://doaj.org/article/3b9ab54a489a475a9778db17045793d4
Autor:
Katharina Jandl, Leigh M. Marsh, Ayse Ceren Mutgan, Slaven Crnkovic, Francesco Valzano, Diana Zabini, Julia Hoffmann, Vasile Foris, Elisabeth Gschwandtner, Walter Klepetko, Helmut Prosch, Holger Flick, Luka Brcic, Izidor Kern, Akos Heinemann, Horst Olschewski, Gabor Kovacs, Grazyna Kwapiszewska
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 207:796-798
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f23d86b5acf99b0f44ab75e60b50a68d
https://doi.org/10.1164/rccm.202212-2214le
https://doi.org/10.1164/rccm.202212-2214le
Autor:
Slaven Crnkovic, Sonja Rittchen, Katharina Jandl, Juergen Gindlhuber, Diana Zabini, Ayse Ceren Mutgan, Francesco Valzano, Panja M. Boehm, Konrad Hoetzenecker, Wolfgang Toller, Christine Veith, Akos Heinemann, Ralph T. Schermuly, Andrea Olschewski, Leigh M. Marsh, Grazyna Kwapiszewska
Publikováno v:
Hypertension. 80
Background: Smooth muscle cell (SMC) expansion is one key morphological hallmark of pathologically altered vasculature and a characteristic feature of pulmonary vascular remodeling in pulmonary hypertension. Normal embryonal vessel maturation require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5998efa6b0063822899ca403dfc2f806
https://doi.org/10.1161/hypertensionaha.122.19479
https://doi.org/10.1161/hypertensionaha.122.19479
Autor:
Ehsan Bonyadi Rad, Anna Birnhuber, Grazyna Kwapiszewska, Bakytbek Egemnazarov, Leigh M. Marsh, Horst Olschewski, Malgorzata Wygrecka, Valentina Biasin
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-5 (2020)
Respiratory Research
Respiratory Research
Inhibitors of cyclin-dependent kinases 4/6 (CDK4/6) block cell cycle progression and are commonly used for treatment of several forms of cancer. Due to their anti-proliferative mode of action, we hypothesized that palbociclib could attenuate the deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e88f7e4ecc69c91ea1dc98fc74b98e49
http://link.springer.com/article/10.1186/s12931-020-01433-w
http://link.springer.com/article/10.1186/s12931-020-01433-w