Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Leigh J. Ellmers"'
Autor:
Miriam T. Rademaker, Anna P. Pilbrow, Leigh J. Ellmers, Suetonia C. Palmer, Trent Davidson, Prisca Mbikou, Nicola J. A. Scott, Elizabeth Permina, Christopher J. Charles, Zoltán H. Endre, A. Mark Richards
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 18 (2021)
BACKGROUND Acute decompensated heart failure (ADHF) is associated with deterioration in renal function—an important risk factor for poor outcomes. Whether ADHF results in permanent kidney damage/dysfunction is unknown. METHODS AND RESULTS We invest
Externí odkaz:
https://doaj.org/article/930d9cc955984a1a8054ae333227dfbe
Autor:
Lee Lee Wong, Miriam T. Rademaker, Eng Leng Saw, Kar Sheng Lew, Leigh J. Ellmers, Christopher J. Charles, Arthur Mark Richards, Peipei Wang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Study of microRNA (miRNAs) using sheep models is limited due to lack of miRNA information. We therefore investigated oar-miRNAs and their regulation in an ovine model of heart failure (HF). Left ventricular (LV) tissue was collected from nor
Externí odkaz:
https://doaj.org/article/65989429538a47d9857a46a93f35e005
Autor:
Evelyn M. Templeton, Anna P. Pilbrow, Torsten Kleffmann, John W. Pickering, Miriam T. Rademaker, Nicola J. A. Scott, Leigh J. Ellmers, Christopher J. Charles, Zoltan H. Endre, A. Mark Richards, Vicky A. Cameron, Moritz Lassé
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6290
Mass spectrometry is a powerful technique for investigating renal pathologies and identifying biomarkers, and efficient protein extraction from kidney tissue is essential for bottom-up proteomic analyses. Detergent-based strategies aid cell lysis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f95b9001e1a0bee655c31cf600cad6c2
https://doi.org/10.3390/ijms24076290
https://doi.org/10.3390/ijms24076290
Autor:
Zoltan H. Endre, Christopher J. Charles, Prisca Mbikou, A. Mark Richards, Leigh J. Ellmers, Elizabeth Permina, Miriam T. Rademaker, Suetonia C. Palmer, Anna P. Pilbrow, Trent Davidson, Nicola J. A. Scott
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 18 (2021)
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
BACKGROUND Acute decompensated heart failure (ADHF) is associated with deterioration in renal function—an important risk factor for poor outcomes. Whether ADHF results in permanent kidney damage/dysfunction is unknown. METHODS AND RESULTS We invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084077aba95f06402ae71d0132a991c8
https://doi.org/10.1161/jaha.121.021312
https://doi.org/10.1161/jaha.121.021312
Autor:
Zoltan H. Endre, Miriam T. Rademaker, Leigh J. Ellmers, Suetonia C. Palmer, Nicola J. A. Scott, Arthur Mark Richards, T Davidson, Christopher J. Charles, Anna P. Pilbrow, Prisca Mbikou
Publikováno v:
European Heart Journal. 41
Background The discovery of new markers for acute kidney injury (AKI) in acute decompensated heart failure (ADHF) has been hampered by an incomplete understanding of the pathological processes underlying AKI in ADHF. Purpose In a sheep model of ADHF,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7350030d3f88485697d1b4b05cb99619
https://doi.org/10.1093/ehjci/ehaa946.0875
https://doi.org/10.1093/ehjci/ehaa946.0875
Autor:
Madhav Bhatia, Chris Frampton, A. Mark Richards, Anna P. Pilbrow, Leigh J. Ellmers, Isao Ishii, Vicky A. Cameron, Philip K. Moore, Evelyn M Templeton
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4284, p 4284 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 12
International Journal of Molecular Sciences
Volume 21
Issue 12
Hydrogen sulfide (H2S) is recognized as an endogenous gaseous signaling molecule generated by cystathionine &gamma
lyase (CSE) in cardiovascular tissues. H2S up-regulation has been shown to reduce ischemic injury, and H2S donors are cardioprotec
lyase (CSE) in cardiovascular tissues. H2S up-regulation has been shown to reduce ischemic injury, and H2S donors are cardioprotec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e64fa28d1037a979970c6460b333be59
https://www.mdpi.com/1422-0067/21/12/4284
https://www.mdpi.com/1422-0067/21/12/4284
Autor:
Evelyn M. Templeton, Moritz Lassé, Torsten Kleffmann, Leigh J. Ellmers, Suetonia C. Palmer, Trent Davidson, Nicola J. A. Scott, John W. Pickering, Christopher J. Charles, Zoltan H. Endre, Vicky A. Cameron, A. Mark Richards, Miriam T. Rademaker, Anna P. Pilbrow
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 1009
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 23, Iss 1009, p 1009 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 23, Iss 1009, p 1009 (2022)
One-quarter of patients with acute decompensated heart failure (ADHF) experience acute kidney injury (AKI)—an abrupt reduction or loss of kidney function associated with increased long-term mortality. There is a critical need to identify early and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::007f0b90ce86c95c39a971df7a95ef13
https://doi.org/10.3390/ijms23021009
https://doi.org/10.3390/ijms23021009
Autor:
Evelyn M Templeton, Trent Davidson, Christopher J. Charles, John W. Pickering, Moritz Lassé, Vicky A. Cameron, Suetonia C. Palmer, Torsten Kleffmann, Leigh J. Ellmers, Nicola J. A. Scott, A.M. Richards, Zoltan H. Endre
Publikováno v:
Heart, Lung and Circulation. 30:S66
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e8929c90f2351a1ce3c23ca75289451
https://doi.org/10.1016/j.hlc.2021.05.020
https://doi.org/10.1016/j.hlc.2021.05.020
Autor:
Timothy G. Yandle, Miriam T. Rademaker, Christopher J. Charles, A. Mark Richards, Leigh J. Ellmers
Publikováno v:
Journal of Cardiac Failure. 22:64-72
The (pro)renin receptor [(P)RR] is implicated in the pathogenesis of cardiovascular disease. We investigated the effects of (P)RR blockade after myocardial infarction (MI) in a mouse coronary-ligation model.Mice underwent sham control surgeries (n =
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa0d016da2eef8c22800ef0a4f724af8
https://doi.org/10.1016/j.cardfail.2015.08.341
https://doi.org/10.1016/j.cardfail.2015.08.341
Publikováno v:
International Journal of Cardiology. 197:56-65
Background Renal dysfunction is a frequent complication and crucial determinant of outcome in acute decompensated heart failure (ADHF). The aim of the study was to assess urocortin 2 (Ucn2) as a short-term therapy in ADHF with a focus on its renal ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0edb481a9eaab6b2525133874ef46c8b
https://doi.org/10.1016/j.ijcard.2015.06.011
https://doi.org/10.1016/j.ijcard.2015.06.011