Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Leigh C. Jefferies"'
Publikováno v:
Clinical Chemistry. 48:150-160
Background: There have been no large-scale analyses of resource utilization comparing the overall costs to treat pediatric patients vs adult patients. Likewise, there have been no studies evaluating the costs of the various components of hospitalizat
Publikováno v:
Clinical Chemistry. 48:140-149
Background: To test the hypothesis that complications increase the use of resources in managing patients in hospitals, we examined the costs of managing patients with the same disease with and without complications. Methods: We used a database develo
Publikováno v:
Transfusion. 41:522-529
BACKGROUND: Transfusion services are frequently challenged to initiate efforts to reduce blood transfusion costs. One approach is to analyze blood transfusion costs for individual medical and surgical Diagnosis-Related Groups (DRGs). Rank ordering of
Publikováno v:
Clinical Chemistry. 46:955-966
Background: To date there have been no studies identifying and comparing the component costs to treat a large number of diseases for hospitalized inpatients. Methods: Hospital costs were analyzed for 486 diagnosis-related groups (DRGs) relating to >1
Publikováno v:
Clinical Chemistry. 46:967-975
Background: To determine the contribution of laboratory costs to the overall costs of managing hospital patients with different diseases, we studied the costs of laboratory testing overall and in relation to the other costs incurred during hospitaliz
Publikováno v:
Transfusion. 39:415-419
BACKGROUND: To fully evaluate the safety and efficacy of umbilical cord blood (UCB) as a source of hematopoietic progenitor cells, UCB banks are being established worldwide to provide a readily accessible resource of stem and progenitor cells for all
Autor:
C Carchidi, Piotr Kraj, Leigh C. Jefferies, D D Biggs, K Anderson, Leslie E. Silberstein, J Goldman
Publikováno v:
Clinical Diagnostic Laboratory Immunology. 2:44-52
To further characterize the B-cell origin of multiple myeloma, our laboratory performed immunoglobulin gene sequence analyses of four cases of myeloma (three immunoglobulin A and one immunoglobulin G). Three tumors expressed VH3 genes and one express
Autor:
Leigh C. Jefferies
Publikováno v:
Hematology/Oncology Clinics of North America. 8:1087-1104
This article describes the autoimmune hemolytic anemias (AIHA), warm reactive AIHA, cold reactive AIHA or cold agglutinin disease (CAD), paroxysmal cold hemoglobinuria, and drug induced hemolytic anemia. Pathogenesis and clinical presentation are dis
Publikováno v:
Clinical Immunology and Immunopathology. 65:119-128
VκIII light (L) chains are commonly expressed by human autoantibodies with diverse binding specificities, including red blood cell antigens. To better understand the physiologic and pathologic expression of these L chain variable region genes, we ha
Autor:
Leigh C. Jefferies, Peter C. Nowell, June Goldman, W Pruzanski, Jean Roudier, Gregg J. Silverman, Jonni S. Moore, David F. Friedman, Leslie E. Silberstein, D Roelcke
Publikováno v:
Blood. 78:2372-2386
To investigate the molecular basis of the autoimmune response to the related i and I carbohydrate antigens, we studied cold agglutinins (CA) from B-cell clones and from the peripheral circulation of patients with lymphoproliferative syndromes. Sequen