Výsledky vyhledávání - "Leigh Bradley"

Loss of Endogenously Cycling Adult Cardiomyocytes Worsens Myocardial Function

Autor: Alexander S. Young, Helen O. Billcheck, Leigh Bradley, Matthew J. Wolf, Hongbin Li

Publikováno v: Circulation Research. 128:155-168

Rationale: Endogenously cycling adult cardiomyocytes increase after myocardial infarction (MI) but remain scarce and are generally thought not to contribute to myocardial function. However, this broadly held assumption has not been tested, mainly bec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f94f6c2c9c82593786eb4ddb7df32f4
https://doi.org/10.1161/circresaha.120.318277

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Ablation of endogenously cycling adult cardiomyocytes worsens myocardial function after injury

Autor: Alexander S. Young, Helen O. Billcheck, Leigh Bradley, Matthew J. Wolf

RationaleEndogenously cycling adult cardiomyocytes (CMs) increase after myocardial infarction (MI) but remain scare, and are generally thought not to contribute to myocardial function. However, this broadly held assumption has not been tested, mainly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a24cefb0ad0b8dc7ca83cf5221ff69df
https://doi.org/10.1101/2020.09.21.306852

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Fibroblast growth factor receptor-3 is expressed in undifferentiated intestinal epithelial cells during murine crypt morphogenesis

Autor: Kirstin Skaar, Alda Vidrich, Steven M. Cohn, Jenny M. Buzan, Leigh Bradley, Chibuzo Ilo

Publikováno v: Developmental Dynamics. 230:114-123

Prior studies have demonstrated that fibroblast growth factor receptor-3 (FGFR-3) regulates proliferation of undifferentiated intestinal epithelial cells in vitro. However, the function(s) of FGFR-3–mediated signaling during intestinal development

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::309d188a8eda86749a138a86aa199adb
https://doi.org/10.1002/dvdy.20018

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Fibroblast growth factor receptor-3 (FGFR-3) regulates expression of paneth cell lineage-specific genes in intestinal epithelial cells through both TCF4/beta-catenin-dependent and -independent signaling pathways

Autor: Brooks Brodrick, Leigh Bradley, Steven M. Cohn, Alda Vidrich, Edith Porter, Jenny M. Buzan

Publikováno v: The Journal of biological chemistry. 286(21)

Fibroblast growth factor receptor-3 (FGFR-3) expression in the developing intestine is restricted to the undifferentiated epithelial cells within the lower portion of the crypt. We previously showed that mice lacking functional FGFR-3 have a signific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa33458e357e4431994731958569686d
https://pubmed.ncbi.nlm.nih.gov/21388956

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Fibroblast growth factor receptor-3 regulates Paneth cell lineage allocation and accrual of epithelial stem cells during murine intestinal development

Autor: Thomas W. Sturgill, Brooks Brodrick, Steven M. Cohn, Jenny M. Buzan, Leigh Bradley, Kirstin Skaar Fendig, Chibuzo Ilo, Alda Vidrich

Publikováno v: American journal of physiology. Gastrointestinal and liver physiology. 297(1)

Fibroblast growth factor receptor 3 (FGFR-3) is expressed in the lower crypt epithelium, where stem cells of the intestine reside. The role of FGFR-3 signaling in regulating features of intestinal morphogenesis was examined in FGFR-3-null (FGFR-3−/

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d492ce9a172fa1bdbedbfda51f9c47e1
https://pubmed.ncbi.nlm.nih.gov/19407216

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