Augmented Parkin-dependent mitophagy underlies the hepatoprotective effect of remote ischemic conditioning used prior to hemorrhagic shock.

Autor: Naraiah Mukkala A; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada., Petrut R; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, Canada., Goldfarb R; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, Canada., Leigh Beroncal E; Department of Pharmacology & Toxicology, University of Toronto, Toronto, Canada., Ho Leung C; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada., Khan Z; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada., Ailenberg M; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, Canada., Jerkic M; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, Canada., Andreazza AC; Department of Pharmacology & Toxicology, University of Toronto, Toronto, Canada., Rhind SG; Defence Research and Development Canada, Department of National Defense, Government of Canada, Toronto, Canada., Jeschke MG; Hamilton Health Sciences Centre and McMaster University, Hamilton, Canada., Kapus A; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada; Department of Surgery, University of Toronto, Toronto, Canada; Department of Biochemistry, University of Toronto, Toronto, Canada., Rotstein OD; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada; Department of Surgery, University of Toronto, Toronto, Canada. Electronic address: Ori.Rotstein@unityhealth.to.

Publikováno v: Mitochondrion [Mitochondrion] 2023 May; Vol. 70, pp. 20-30. Date of Electronic Publication: 2023 Mar 10.

MKK3 depletion attenuates intestinal injury after traumatic hemorrhagic shock by restoring mitochondrial function.

Autor: Li L; Department of Emergency Surgery, The First Affiliated Hospital of Bengbu Medical University, 287 Chang Huai Road, Bengbu, Anhui, 233099, China.; Suzhou Medical college of Soochow University, Suzhou, Jiangsu, 215123, China., Zhang Z; Department of Emergency Surgery, The First Affiliated Hospital of Bengbu Medical University, 287 Chang Huai Road, Bengbu, Anhui, 233099, China., Kuai X; Department of Emergency Surgery, The First Affiliated Hospital of Bengbu Medical University, 287 Chang Huai Road, Bengbu, Anhui, 233099, China., Deng J; Department of Emergency Surgery, The First Affiliated Hospital of Bengbu Medical University, 287 Chang Huai Road, Bengbu, Anhui, 233099, China., Qiu Z; Department of Emergency Surgery, The First Affiliated Hospital of Bengbu Medical University, 287 Chang Huai Road, Bengbu, Anhui, 233099, China.; Suzhou Medical college of Soochow University, Suzhou, Jiangsu, 215123, China., Wang Z; Department of Emergency Surgery, The First Affiliated Hospital of Bengbu Medical University, 287 Chang Huai Road, Bengbu, Anhui, 233099, China., Jiang H; Department of Emergency Surgery, The First Affiliated Hospital of Bengbu Medical University, 287 Chang Huai Road, Bengbu, Anhui, 233099, China. jianghaidoctor@163.com.; Suzhou Medical college of Soochow University, Suzhou, Jiangsu, 215123, China. jianghaidoctor@163.com.

Publikováno v: Molecular biology reports [Mol Biol Rep] 2024 Jun 21; Vol. 51 (1), pp. 776. Date of Electronic Publication: 2024 Jun 21.