Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Leigh B. Kleinert"'
Publikováno v:
Cell Transplantation, Vol 5 (1996)
Endothelial cell transplantation onto polymeric vascular grafts results in the formation of a neointima. The formation of this neointima is often suggested to result from a chronic cellular hyperplasia where the terms intimal hyperplasia and intimal
Externí odkaz:
https://doaj.org/article/0ebb3c10ca2f435d898edfb7ae1fec04
Autor:
Leigh B. Kleinert, Stuart K. Williams, Kevin D. Lye, Charles B. Ross, Gary D Gentzkow, Paul E. Kosnik, Amit J Dwevidi, Marvin E. Morris
Publikováno v:
Tissue engineering. Part C, Methods. 23(8)
Adipose-derived stromal vascular fraction (SVF) cell populations are being evaluated for numerous clinical applications. The current study evaluated a point-of-care technology, the Tissue Genesis "TGI 1000" Cell Isolation System™, to perform an aut
Publikováno v:
Journal of Biomedical Materials Research Part A. :67-73
Development of a small diameter (6 mm) synthetic vascular graft with clinically acceptable patency must overcome the inherent thrombogenicity of polymers and the development of neointimal thickening. Establishment of an endothelial cell lining on the
Publikováno v:
Journal of Biomedical Materials Research Part A. :59-65
Healing associated with many polymeric biomedical implants commonly involves the formation of an avascular fibrous capsule. The lack of either formation or persistence of blood vessels in formed fibrous capsules, as well as a lack of new blood vessel
Autor:
Vangie B. Patula, Paul Martakos, Leigh B. Kleinert, Ted Karwoski, Stuart K. Williams, John P. Lane
Publikováno v:
Plastic and Reconstructive Surgery. 115:1995-2006
Background: A variety of nondegradable polymers have been evaluated for use as soft-tissue augmentation devices. This study compared a novel dual porosity expanded polytetrafluoroethylene with current, clinically used devices. Methods: Studies were p
Publikováno v:
Journal of Biomedical Materials Research. 49:489-497
The chronic inflammatory response associated with the abluminal surface of polymeric vascular grafts has been suggested to affect adversely graft neovascularization, the cellular response at the luminal surface of vascular grafts, and overall graft p
Publikováno v:
Perfusion. 15:13-20
Heparin-bonded perfusion circuits have been reported to reduce the thrombus formation during various levels of systemic heparinization. The goal of this study was to compare the efficacy of thrombo-resistance of the Sarns 3M heparin-bonded circuit to
Publikováno v:
Cardiovascular Pathology. 8:63-71
This study was designed to evaluate and compare healing characteristics, specifically neovascularization and inflammation, of polymeric vascular graft materials commonly used in clinical applications. Our hypotheses were (i) polymeric materials used
Publikováno v:
Journal of Biomedical Materials Research. 35:473-481
The preclinical evaluation of polymer biocompatibility is often performed using animal subcutaneous implant models. The choice of subcutaneous tissue as the implant site is due to a number of factors including simplicity of the surgery involved. Resu
Publikováno v:
Journal of Biomedical Materials Research. 34:463-476
Healing of biomaterial implants varies depending on the type and structure of material and the tissue surrounding the implant. In this study we examined structural differences of 30 microm, 60 microm, and 100 microm expanded polytetrafluoroethylene (