Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Leigh Anne F. Ihnken"'
Autor:
Sandy S. Chang, Joseph Hosford, Mahesh J. Sanganee, Anne A. Ollis, Christopher M. MacDermaid, Leigh Anne F. Ihnken, Murray J. B. Brown, Douglas E. Fuerst, Jonathan Latham, Diluar Khan, Markus Schober, Gheorghe-Doru Roiban
Publikováno v:
Nature Catalysis. 2:909-915
Imine reductases catalyse the reductive amination of aldehydes or ketones with amines to produce chiral amines—a key transformation in the preparation of fine chemicals and active pharmaceutical ingredients. Although significant progress has been r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1c5679819baaf967e2370855b4545f2
https://doi.org/10.1038/s41929-019-0341-4
https://doi.org/10.1038/s41929-019-0341-4
Autor:
Marcelo Kern, Kristin K. Brown, Lydia Sanchez Jordan, Gheorghe-Doru Roiban, Pei Lyn Tey, Leigh Anne F. Ihnken, Julia F. Hyslop, Zhi Liu, Murray J. B. Brown, Matthew S. Levine, Timin Hadi
Publikováno v:
ChemCatChem. 9:4475-4479
Chiral secondary and tertiary amines are ubiquitous in pharmaceutical, fine, and specialty chemicals, but their synthesis typically suffers from significant sustainability and selectivity challenges. Biocatalytic alternatives, such as enzyme-catalyze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9619a60f252270abd98864f3eda170e8
https://doi.org/10.1002/cctc.201701379
https://doi.org/10.1002/cctc.201701379
Autor:
Gheorghe-Doru Roiban, Cyril Boudet, Paul Homes, Kristin K. Brown, Jiasheng Guo, Douglas E. Fuerst, Alison S. Dann, Andrew P. Fosberry, Christopher Morgan, Rebecca Splain, Peter W. Sutton, Katherine Joyce Honicker, Leigh Anne F. Ihnken
Publikováno v:
Organic Process Research & Development. 21:1302-1310
An epoxide resolution process was rapidly developed that allowed access to multigram scale quantities of (R)-2-butyl-2-ethyloxirane 2 at greater than 300 g/L reaction concentration using an easy-to-handle and store lyophilized powder of epoxide hydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5316117ac33fa0f397c3d81dc1e0d07
https://doi.org/10.1021/acs.oprd.7b00179
https://doi.org/10.1021/acs.oprd.7b00179