Výsledky vyhledávání - "Leigh Ann Bush"

A novel asparaginase-like protein is a sperm autoantigen in rats

Autor: Leigh Ann Bush, Nicholas E. Sherman, Charles J. Flickinger, John C. Herr, Amy N Shore, Michael J. Wolkowicz

Publikováno v: Molecular Reproduction and Development. 62:233-247

A novel asparaginase-like protein (ALP) of spermatozoa was cloned from rat and human testis cDNA libraries on the basis of reactivity with antibodies produced after vasectomy. Although obstruction of the male reproductive tract is known to cause an i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d9369ac8b18c9fc37034063997f23e6
https://doi.org/10.1002/mrd.10092

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CABYR, a Novel Calcium-Binding Tyrosine Phosphorylation-Regulated Fibrous Sheath Protein Involved in Capacitation

Autor: Charles J. Flickinger, Jagathpala Shetty, Michael J. Wolkowicz, Young-Howan Kim, Buer Sen, Leigh Ann Bush, Kenneth L. Klotz, Scott A. Coonrod, John C. Herr, Arabinda Mandal, V. Anne Westbrook, Soren Naaby-Hansen

Publikováno v: Developmental Biology. 242(2):236-254

To reach fertilization competence, sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d76eaef20cf4fd57553ff45bd95b51e2

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Co-localization of the inositol 1,4,5-trisphosphate receptor and calreticulin in the equatorial segment and in membrane bounded vesicles in the cytoplasmic droplet of human spermatozoa

Autor: Michael J. Wolkowicz, Scott A. Coonrod, Leigh Ann Bush, V. Anne Westbrook, Nicholas E. Sherman, Michael Kinter, Charles J. Flickinger, Jagathpala Shetty, Jay W. Fox, John D. Shannon, Ken Klotz, Prabhakara Poothi Reddi, Soren Naaby-Hansen, John C. Herr, Hiroaki Shibahara

Publikováno v: Molecular Human Reproduction. 7:923-933

Modulation of the intracellular calcium concentration within mammalian spermatozoa is important in several pre-fertilization events including hyperactivated motility and the acrosome reaction. To identify calcium binding proteins (CBP) potentially re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2c25ef5a788ae7290019391c9aa682
https://doi.org/10.1093/molehr/7.10.923

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Outer Dense Fiber Proteins Are Dominant Postobstruction Autoantigens in Adult Lewis Rats1

Autor: Charles J. Flickinger, Nicholas E. Sherman, Leigh Ann Bush, John C. Herr, Friederike L. Jayes, Jayasimha Rao, Richard Oko

Publikováno v: Biology of Reproduction. 64:1451-1459

Obstruction of the male reproductive tract commonly results in generation of antisperm autoantibodies. However, only a few of the sperm autoantigens recognized by these antibodies have been characterized. To identify postobstruction rat sperm autoant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::944736ebf4614ed684676447a1a7b976
https://doi.org/10.1095/biolreprod64.5.1451

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Sperm Mitochondria-Associated Cysteine-Rich Protein (SMCP) Is an Autoantigen in Lewis Rats1

Autor: Stuart S. Howards, John C. Herr, Leigh Ann Bush, Vrinda Khole, David Thomas, Scott A. Coonrod, Charles J. Flickinger

Publikováno v: Biology of Reproduction. 61:428-435

A common repertoire of rat sperm antigens have previously been identified by Western blotting of sperm proteins with sera obtained after vasectomy or isoimmunization with sperm. Aside from a determination of their apparent masses, however, the bioche

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a3387dd2c587ac0449512f0cb8004d82
https://doi.org/10.1095/biolreprod61.2.428

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Post-obstruction rat sperm autoantigens identified by two-dimensional gel electrophoresis and western blotting

Autor: Mollie V Williams, Soren Naaby-Hansen, Leigh Ann Bush, Charles J. Flickinger, John C. Herr, Stuart S. Howards

Publikováno v: Journal of Reproductive Immunology. 43:35-53

Although antisperm autoantibody responses to obstruction of the male reproductive system have been documented, information on the nature of the cognate sperm autoantigens has been limited. In the present study, the patterns of sperm autoantigens reco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc4d839bf544a621ab8af9350cdfb39
https://doi.org/10.1016/s0165-0378(98)00090-4

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Distribution of leukocytes in the epithelium and interstitium of four regions of the Lewis rat epididymis

Autor: Leigh Ann Bush, Stuart S. Howards, Charles J. Flickinger, John C. Herr

Publikováno v: The Anatomical Record. 248:380-390

BACKGROUND Leukocytes expressing different surface markers were studied in four regions of the epididymis of Lewis rats. Cells resembling lymphocytes or monocytes had been described in the epididymis, but previous studies differed as to their nature

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::06f91977040abbb517e6d677543b4058
https://doi.org/10.1002/(sici)1097-0185(199707)248:3<380::aid-ar11>3.0.co

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Antisperm autoantibody responses to vasectomy and vasovasostomy in Fischer and Lewis rats

Autor: Stuart S. Howards, John C. Herr, Leigh Ann Bush, Charles J. Flickinger, Linda A. Baker

Publikováno v: Journal of Reproductive Immunology. 28:137-157

Antisperm autoanitbodies were studied in Fischer and Lewis strains of rats after either vasectomy, vasectomy followed one month later by vasovasostomy, or sham operations. The time course of antibody response to sperm protein autoantigens was assayed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::363c78925525c3053b2386fa49fc4687
https://doi.org/10.1016/0165-0378(94)00904-l

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