Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Leigh A. Johnston"'
Autor:
Gihan P. Ruwanpathirana, Robert C. Williams, Colin L. Masters, Christopher C. Rowe, Leigh A. Johnston, Catherine E. Davey
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 1, Pp n/a-n/a (2024)
Abstract INTRODUCTION The standardized uptake value ratio (SUVR) is used to measure amyloid beta–positron emission tomography (Aβ‐PET) uptake in the brainDifferences in PET scanner technologies and image reconstruction techniques can lead to var
Externí odkaz:
https://doaj.org/article/de770e2eda324ed38d087dba69ea9f50
Autor:
Gihan P. Ruwanpathirana, Robert C. Williams, Colin L. Masters, Christopher C. Rowe, Leigh A. Johnston, Catherine E. Davey
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract In Alzheimer’s disease, the molecular pathogenesis of the extracellular Aβ-amyloid (Aβ) instigation of intracellular tau accumulation is poorly understood. We employed a high-resolution PET scanner, with low detection thresholds, to exam
Externí odkaz:
https://doaj.org/article/f88040d715a242fe8fcfbc3894d76403
Autor:
Vanessa H. Brait, David K. Wright, Mohsen Nategh, Alexander Oman, Warda T. Syeda, Charlotte M. Ermine, Katrina R. O’Brien, Emilio Werden, Leonid Churilov, Leigh A. Johnston, Lachlan H. Thompson, Jess Nithianantharajah, Katherine A. Jackman, Amy Brodtmann
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Hippocampal atrophy is increasingly described in many neurodegenerative syndromes in humans, including stroke and vascular cognitive impairment. However, the progression of brain volume changes after stroke in rodent models is poorly charact
Externí odkaz:
https://doaj.org/article/733fd8e8fe89434284c6d4ddeaa6db91
Autor:
Gihan P. Ruwanpathirana, Darren C. Plett, Robert C. Williams, Catherine E. Davey, Leigh A. Johnston, Herbert J. Kronzucker
Publikováno v:
Plant Methods, Vol 17, Iss 1, Pp 1-12 (2021)
Abstract Background The absorption, translocation, accumulation and excretion of substances are fundamental processes in all organisms including plants, and have been successfully studied using radiotracers labelled with 11C, 13N, 14C and 22Na since
Externí odkaz:
https://doaj.org/article/d72c7e05a8f94a3498fd808eb1209de0
Autor:
Warda T. Syeda, Cassandra M.J. Wannan, Antonia H. Merritt, Jayachandra M. Raghava, Mahesh Jayaram, Dennis Velakoulis, Tina D. Kristensen, Rigas Filippos Soldatos, Shane Tonissen, Naveen Thomas, Karen S. Ambrosen, Mikkel E. Sørensen, Birgitte Fagerlund, Egill Rostrup, Birte Y. Glenthøj, Efstratios Skafidas, Chad A. Bousman, Leigh A. Johnston, Ian Everall, Bjørn H. Ebdrup, Christos Pantelis
Publikováno v:
NeuroImage: Clinical, Vol 35, Iss , Pp 103064- (2022)
Background: Brain structural alterations and cognitive dysfunction are independent predictors for poor clinical outcome in schizophrenia, and the associations between these domains remains unclear. We employed a novel, multiblock partial least square
Externí odkaz:
https://doaj.org/article/834de1c211e54523aea646e22a0f78b8
Autor:
Negin Yaghmaie, Warda T. Syeda, Chengchuan Wu, Yicheng Zhang, Tracy D. Zhang, Emma L. Burrows, Amy Brodtmann, Bradford A. Moffat, David K. Wright, Rebecca Glarin, Scott Kolbe, Leigh A. Johnston
Publikováno v:
NeuroImage, Vol 231, Iss , Pp 117701- (2021)
Purpose: Quantitative susceptibility mapping (QSM) is a novel MR technique that allows mapping of tissue susceptibility values from MR phase images. QSM is an ill-conditioned inverse problem, and although several methods have been proposed in the fie
Externí odkaz:
https://doaj.org/article/c95ebddf7d984e6e88c6fa002da780fd
Autor:
Rosita Shishegar, Fabrizio Pizzagalli, Nellie Georgiou-Karistianis, Gary F. Egan, Neda Jahanshad, Leigh A. Johnston
Publikováno v:
NeuroImage, Vol 229, Iss , Pp 117751- (2021)
An accurate measure of the complexity of patterns of cortical folding or gyrification is necessary for understanding normal brain development and neurodevelopmental disorders. Conventional gyrification indices (GIs) are calculated based on surface cu
Externí odkaz:
https://doaj.org/article/298303335f7d4cd1a13284edcbbfe07c
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
In this work fMRI BOLD datasets are shown to contain slice-dependent non-stationarities. A model containing slice-dependent, non-stationary signal power is proposed to address time-varying signal power during BOLD data acquisition. The impact of non-
Externí odkaz:
https://doaj.org/article/96d3b2f247c243e182ec331eb4871b35
Autor:
Scott C. Kolbe, Warda Syeda, Yasmin Blunck, Rebecca Glarin, Meng Law, Leigh A. Johnston, Jon O. Cleary
Publikováno v:
NeuroImage, Vol 211, Iss , Pp 116609- (2020)
23Na provides the second strongest MR-observable signal in biological tissue and exhibits bi-exponential T2∗ relaxation in micro-environments such as the brain. There is significant interest in developing 23Na biomarkers for neurological diseases t
Externí odkaz:
https://doaj.org/article/0347f78bbab540db83b1be9ea0dcda3f
Autor:
Pragati Sharma, David K. Wright, Leigh A. Johnston, Kim L. Powell, Mary E. Wlodek, Sandy R. Shultz, Terence J. O'Brien, Krista L. Gilby
Publikováno v:
Neurobiology of Disease, Vol 104, Iss , Pp 33-40 (2017)
Alterations in white matter integrity have been well documented in chronic epilepsy and during epileptogenesis. However, the relationship between white matter integrity and a predisposition towards epileptogenesis has been understudied. The FAST rat
Externí odkaz:
https://doaj.org/article/77ba12423dd142f38dc5193a259148fa