Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Leigh A Nattkemper"'
Autor:
Alexandru D P Papoiu, Leigh A Nattkemper, Kristen M Sanders, Robert A Kraft, Yiong-Huak Chan, Robert C Coghill, Gil Yosipovitch
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82389 (2013)
Previous brain imaging studies investigating the brain processing of scratching used an exogenous intervention mimicking scratching, performed not by the subjects themselves, but delivered by an investigator. In real life, scratching is a conscious,
Externí odkaz:
https://doaj.org/article/17986f523a6943dca770e40f5cef3b82
Autor:
Leigh A. Nattkemper, Ashley Vander Does, Carolyn M. Stull, Michael J. Lavery, Rodrigo Valdes-Rodriguez, Marlene McGregory, Yiong Huak Chan, Gil Yosipovitch
Publikováno v:
Acta Dermato-Venereologica, Vol 103 (2023)
Botulinum toxin type A (Botox®) is thought to have antipruritic effects through inhibition of pruritic factors, including acetylcholine, substance P, and glutamate. The aim of this randomized, single-blind, placebo-controlled trial was to test the e
Externí odkaz:
https://doaj.org/article/3d50919096ac4fc99bf6891ae39f29b9
Autor:
Leigh A. Nattkemper, Zoe M. Lipman, Giuseppe Ingrasci, Claudia Maldonado, Juan Carlos Garces, Enrique Loayza, Gil Yosipovitch
Publikováno v:
Acta Dermato-Venereologica, Vol 103 (2023)
Scalp psoriatic itch is a common, bothersome, yet understudied, condition with numerous associated treatment challenges. The aim of this study was to enhance our understanding of the pathophysiology of scalp psoriatic itch. Immunohistochemical analys
Externí odkaz:
https://doaj.org/article/fdfc0a2d0d72461b936ac95ec09fc0a7
Publikováno v:
Allergology International, Vol 66, Iss 1, Pp 14-21 (2017)
Atopic dermatitis (AD) is a common chronic skin disease that is characterized by intense pruritus and has high impairment of quality of life. AD is often described as “the itch that rashes, rather than the rash that itches”. Several studies sugge
Externí odkaz:
https://doaj.org/article/7343e4f908e94287935f44b2a7cbe5a8
Autor:
Franz J. Legat, Leigh A. Nattkemper, B. Sadoghi, Jeffrey D. Bernhard, Sonja Ständer, Gil Yosipovitch, Elke Weisshaar, Claudia Zeidler, H. Hait, Jacek C Szepietowski, T. R. Sciascia, Adam Reich
Publikováno v:
Journal of the European Academy of Dermatology and Venereology. 36:453-461
BACKGROUND Treatment of prurigo nodularis (PN) is challenging and new treatment options are needed. OBJECTIVE To evaluate the efficacy and safety of two oral doses of the kappa opioid agonist and mu opioid antagonist nalbuphine extended release (NAL-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46894b064141b2b7b0b6c33ed5be95a5
https://doi.org/10.1111/jdv.17816
https://doi.org/10.1111/jdv.17816
Autor:
John F. Paolini, Leigh A. Nattkemper, Hei Sung Kim, Paolo Romanelli, Sonali Nanda, Serena M. Shah, Gil Yosipovitch, Takashi Hashimoto, Emilie Fowler, Christina D. Kursewicz, Rachel Fayne
Publikováno v:
Experimental Dermatology. 30:804-810
Prurigo nodularis (PN) is a chronic skin dermatosis with hyperkeratotic and intensely pruritic nodules. Managing PN-associated itch is difficult because its aetiology is still unknown. This study aimed to investigate the correlation between itch inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49c277f26859807b4ea80c1d93200e2f
https://doi.org/10.1111/exd.14279
https://doi.org/10.1111/exd.14279
Publikováno v:
F1000Research, Vol 5 (2016)
Chronic itch is a significant health burden with few effective treatments. As such, itch researchers seek to understand the mechanisms behind itch and to find potential targets for treatment. The field of itch research is dynamic, and many advances h
Externí odkaz:
https://doaj.org/article/e86a5f6704f147b8adb0a711530ebdc2
Autor:
Leigh A. Nattkemper, Sonali Nanda, Serena M. Shah, Hiroo Yokozeki, Rachel Fayne, Christina D. Kursewicz, Gil Yosipovitch, Takashi Hashimoto
Publikováno v:
Journal of the American Academy of Dermatology. 83:53-62
Background One of the hallmarks of bullous pemphigoid (BP) is moderate to severe chronic itch. Managing this is difficult because little is known about the mechanisms of itch in BP. Objective We sought to elucidate the pathophysiologic mechanisms of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::648ee4b10b355e589a41b18220648fdb
https://doi.org/10.1016/j.jaad.2019.07.060
https://doi.org/10.1016/j.jaad.2019.07.060
Autor:
Leigh A. Nattkemper, Flor MacQuhae, Kaining Zhi, Yiong Huak Chan, Rachel Shireen Golpanian, Kayla Fourzali, Serena M. Shah, David B Lebo, Kaeli E Romero, Terresa Ju, Gil Yosipovitch
Publikováno v:
Acta Dermato-Venereologica, Vol 102 (2022)
There is a need for new topical antipruritics that are effective on many types of itch. This study examined the antipruritic efficacy of a new formulation of topical acetaminophen. In vitro skin permeability studies showed that 2.5% and 5% formulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd97cc56b1abef54bcd4b21f6c5f6cf4
https://medicaljournalssweden.se/actadv/article/view/1098
https://medicaljournalssweden.se/actadv/article/view/1098
Publikováno v:
Journal of Investigative Dermatology. 141:1586-1588
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd38c9ccae0a31f79918c12dc945f9bf
https://doi.org/10.1016/j.jid.2020.11.017
https://doi.org/10.1016/j.jid.2020.11.017