Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Leif A. Havton"'
Autor:
Juan C. Sáez, Justin C. Burrell, Catherine M. Cahill, D. Kacy Cullen, Lakshmi A. Devi, Ryan J. Gilbert, Zachary A. Graham, Vadim J. Gurvich, Leif A. Havton, Ravi Iyengar, Rajesh Khanna, Edmund F. Palermo, Mustafa Siddiq, Carlos A. Toro, Walter Vasquez, Wei Zhao, Christopher P. Cardozo
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Over the past decade, boldine, a naturally occurring alkaloid found in several plant species including the Chilean Boldo tree, has garnered attention for its efficacy in rodent models of human disease. Some of the properties that have been attributed
Externí odkaz:
https://doaj.org/article/07edf235e1324a7b9a58860ef7edcbde
Autor:
Jared M. Sprague, Ajay S. Yekkirala, Bhagat Singh, Ivan Tochitsky, Michael Stephens, Octavio Viramontes, Jelena Ivanis, Natalia P. Biscola, Leif A. Havton, Clifford J. Woolf, Alban Latremoliere
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract TRPV1 is an ion channel that transduces noxious heat and chemical stimuli and is expressed in small fiber primary sensory neurons that represent almost half of skin nerve terminals. Tissue injury and inflammation result in the sensitization
Externí odkaz:
https://doaj.org/article/29cb07f8d3904765814dfa76b8f551c4
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Lower urinary tract (LUT) dysfunction is prevalent in the elderly population, and clinical manifestations include urinary retention, incontinence, and recurrent urinary tract infections. Age-associated LUT dysfunction is responsible for sign
Externí odkaz:
https://doaj.org/article/6bfcc151baa941428720332781bb8839
Autor:
Abida Sanjana Shemonti, Emanuele Plebani, Natalia P. Biscola, Deborah M. Jaffey, Leif A. Havton, Janet R. Keast, Alex Pothen, M. Murat Dundar, Terry L. Powley, Bartek Rajwa
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
A thorough understanding of the neuroanatomy of peripheral nerves is required for a better insight into their function and the development of neuromodulation tools and strategies. In biophysical modeling, it is commonly assumed that the complex spati
Externí odkaz:
https://doaj.org/article/ec13564424114d20b07151bd0525e319
Autor:
Emanuele Plebani, Natalia P. Biscola, Leif A. Havton, Bartek Rajwa, Abida Sanjana Shemonti, Deborah Jaffey, Terry Powley, Janet R. Keast, Kun-Han Lu, M. Murat Dundar
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Axonal characterizations of connectomes in healthy and disease phenotypes are surprisingly incomplete and biased because unmyelinated axons, the most prevalent type of fibers in the nervous system, have largely been ignored as their quantita
Externí odkaz:
https://doaj.org/article/eeebcd4fdbae4233a1b78aa47374606f
Autor:
Leif A. Havton, Natalia P. Biscola, Esther Stern, Plamen V. Mihaylov, Chandrashekhar A. Kubal, John M. Wo, Anita Gupta, Elizabeth Baronowsky, Matthew P. Ward, Deborah M. Jaffey, Terry L. Powley
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The vagus nerve provides motor, sensory, and autonomic innervation of multiple organs, and electrical vagus nerve stimulation (VNS) provides an adjunctive treatment option for e.g. medication-refractory epilepsy and treatment-resistant depre
Externí odkaz:
https://doaj.org/article/3f2388bdac874793b9114a2a90670f8a
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Segmentation of axons in light and electron micrographs allows for quantitative high-resolution analysis of nervous tissues, but varied axonal dispersion angles result in over-estimates of fiber sizes. To overcome this technical challenge, w
Externí odkaz:
https://doaj.org/article/d308ae6b0d4644f4b4372080c4c76db5
Publikováno v:
Frontiers in Neurology, Vol 8 (2017)
Injuries to the conus medullaris and cauda equina portions of the spinal cord result in neurological impairments, including paralysis, autonomic dysfunction, and pain. In experimental studies, earlier investigations have shown that a lumbosacral vent
Externí odkaz:
https://doaj.org/article/5857527cfddf42848613cab7cc913fec
Autor:
Dongxiao Yan, Ahmad A. Jiman, Elizabeth C. Bottorff, Paras R. Patel, Dilara Meli, Elissa J. Welle, David C. Ratze, Leif A. Havton, Cynthia A. Chestek, Stephen W. P. Kemp, Tim M. Bruns, Euisik Yoon, John P. Seymour
Publikováno v:
Small
Peripheral nerve mapping tools with higher spatial resolution are needed to advance systems neuroscience, and potentially provide a closed-loop biomarker in neuromodulation applications. Two critical challenges of microscale neural interfaces are (i)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36fb21e378ed522cfed509d1a5685437
https://europepmc.org/articles/PMC9167574/
https://europepmc.org/articles/PMC9167574/
Autor:
Mohammed A. Swid, Leif A. Havton, Peter Hanna, Elizabeth H. Smith, Sirisha Achanta, Jeffrey L. Ardell, John D. Tompkins, Pradeep S. Rajendran, Robert L. Lux, Natalia P. Biscola, Kalyanam Shivkumar, Alison Moss, Jin Chen, Joseph Hadaya, Jaclyn A. Brennan, Igor R. Efimov, Rajanikanth Vadigepalli, Zixi (Jack) Cheng, James S. Schwaber, Michael J. Dacey, Shaina Robbins, Donald B. Hoover, Shumpei Mori, Stanley G. Peirce
Publikováno v:
Circ Res
Circulation research, vol 128, iss 9
Circulation research, vol 128, iss 9
Rationale: Cardiac function is under exquisite intrinsic cardiac neural control. Neuroablative techniques to modulate control of cardiac function are currently being studied in patients, albeit with variable and sometimes deleterious results. Objecti