Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Leif‐Alexander Garbe"'
Autor:
Fabien Schultz, Leif‐Alexander Garbe
Publikováno v:
Pharmacology Research & Perspectives, Vol 11, Iss 4, Pp n/a-n/a (2023)
Abstract Ethnopharmacology seeks to investigate humankind's use of natural materials, such as plants, fungi, microorganisms, animals, and minerals, for medicinal purposes. In this highly interdisciplinary field, which can be described as a bridge bet
Externí odkaz:
https://doaj.org/article/5ab29c6d3a094b058c2e9dff73a41ba7
Autor:
Fabien Schultz, Godwin Anywar, Huaqiao Tang, François Chassagne, James T. Lyles, Leif-Alexander Garbe, Cassandra L. Quave
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-19 (2020)
Abstract Antibiotic resistance poses one of the greatest threats to global health today; conventional drug therapies are becoming increasingly inefficacious and limited. We identified 16 medicinal plant species used by traditional healers for the tre
Externí odkaz:
https://doaj.org/article/644cd8eae24945c5b0a551c9508ba234
Autor:
Lyudmyla Antypenko, Fatuma Meyer, Zhanar Sadyk, Konstyantyn Shabelnyk, Sergiy Kovalenko, Karl Gustav Steffens, Leif-Alexander Garbe
Publikováno v:
Journal of Fungi, Vol 9, Iss 1, p 79 (2023)
Agents with antifungal activity play a vital role as therapeutics in health care, as do fungicides in agriculture. Effectiveness, toxicological profile, and eco-friendliness are among the properties used to select suitable substances. Furthermore, a
Externí odkaz:
https://doaj.org/article/d1c051f34502463097044be1c60453ef
Publikováno v:
Acta Chimica Slovenica, Vol 66, Iss 4, Pp 784-791 (2019)
Tacrolimus (FK506) is an immunosuppressant drug widely used to avoid organ rejection in transplant patients. It has a profound influence on the cellular stress response by interfering with the calmodulin-calcineurin signaling pathway. In this context
Externí odkaz:
https://doaj.org/article/d7d7a0e8bf774c6598366ab2de2eaffd
Autor:
Fabien Schultz, Ogechi Favour Osuji, Anh Nguyen, Godwin Anywar, John R. Scheel, Guy Caljon, Luc Pieters, Leif-Alexander Garbe
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
We investigated the potential antimalarial and toxicological effects of 16 medicinal plants frequently used by traditional healers to treat malaria, fever, and related disorders in the Greater Mpigi region in Uganda. Species studied were Albizia cori
Externí odkaz:
https://doaj.org/article/80065e1020194cb4b0525ad6c3a7a263
Autor:
Lyudmyla Antypenko, Fatuma A. Hassan, Zhanar Sadykova, Leif-Alexander Garbe, Karl G. Steffens
Publikováno v:
Acta Chimica Slovenica, Vol 65, Iss 4, Pp 836-841 (2018)
Antifungal activity of suberic acid monomethyl ester (monomethyl suberate) was investigated in a growth inhibition assay comprising of 11 different fungi and 3 Phytophthora oomycetes strains relevant in agriculture. In comparison to standard antifung
Externí odkaz:
https://doaj.org/article/d58490109d864be8979419e99211bd83
Publikováno v:
Plants, Vol 10, Iss 2, p 351 (2021)
Our study investigates 16 medicinal plants via assessment of inhibition of proinflammatory enzymes such as cyclooxygenases (COX). The plants are used by traditional healers in the Greater Mpigi region in Uganda to treat inflammation and related disor
Externí odkaz:
https://doaj.org/article/8b16643236ed404f925696419da76d1c
Autor:
Emily Eva Holmes, Maria Jung, Sebastian Meller, Annette Leisse, Verena Sailer, Julie Zech, Martina Mengdehl, Leif-Alexander Garbe, Barbara Uhl, Glen Kristiansen, Dimo Dietrich
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93933 (2014)
DNA methylation analyses usually require a preceding bisulfite conversion of the DNA. The choice of an appropriate kit for a specific application should be based on the specific performance requirements with regard to the respective sample material.
Externí odkaz:
https://doaj.org/article/a90a3a3ff8a24aaaa9575fa996cb8bc0
Publikováno v:
Video Journal of Education and Pedagogy. 6:1-15
In ethnopharmacology, scientists often survey indigenous communities to identify and collect natural remedies such as medicinal plants that are yet to be investigated pharmacologically in a laboratory setting. The Nagoya Protocol provided internation
Publikováno v:
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-Based Complementary and Alternative Medicine, Vol 2021 (2021)
Evidence-Based Complementary and Alternative Medicine, Vol 2021 (2021)
In ethnopharmacological research, many field assessment tools exist. Yet, these miss that critical point of how to really determine which species merit the costly lab studies, e.g., evaluation of traditional use via pharmacological assays and isolati