Výsledky vyhledávání - "Leide Laura Figueiredo Maciel"

Akademický článek

In Vitro and In Vivo Relevant Antineoplastic Activity of Platinum(II) Complexes toward Triple-Negative MDA-MB-231 Breast Cancer Cell Line

Autor: Leide Laura Figueiredo Maciel, Marina Barreto Silva, Rafaela Oliveira Moreira, Ana Paula Cardoso, Christiane Fernandes, Adolfo Horn, João Carlos de Aquino Almeida, Milton Masahiko Kanashiro

Publikováno v: Pharmaceutics, Vol 14, Iss 10, p 2013 (2022)

Two platinum complexes [Pt(HL3)Cl]·H2O (3) and [Pt(HL4)Cl]·H2O (4) containing α- and β-naphthyl groups, respectively, were investigated in more detail in vitro and in vivo for antineoplastic activity. The cytotoxicity activity induced by these pl

Externí odkaz: https://doaj.org/article/654ed0d712f9487c84412439a6d21cb9

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Antitumor activity via apoptotic cell death pathway of water soluble copper(II) complexes: effect of the diamino unit on selectivity against lung cancer NCI-H460 cell line

Autor: Milton M. Kanashiro, Rafaela R. Moreira, Leide Laura Figueiredo Maciel, Adolfo Horn, João Carlos de Aquino Almeida, Érika S. Bull, Samila R. Morcelli, Christiane Fernandes, Wagner da Silva Terra

Publikováno v: BioMetals. 34:661-674

The cytotoxicity against five human tumor cell lines (THP-1, U937, Molt-4, Colo-205 and NCI-H460) of three water soluble copper(II) coordination compounds containing the ligands 3,3′-(ethane-1,2-diylbis(azanediyl))dipropanamide (BCEN), 3,3′-(pipe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5e8e3e716d8e76fb56ec5b9ce1cc2344
https://doi.org/10.1007/s10534-021-00302-3

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Modulating the antitumoral activity by the design of new platinum(II) compounds: Synthesis, characterization, DFT, ultrastructure and mechanistic studies

Autor: Rafaela Oliveira Moreira, Jackson A. L. C. Resende, Christiane Fernandes, Samila R. Morcelli, Leide Laura Figueiredo Maciel, Lawrence R. Gahan, Adolfo Horn, João Carlos de Aquino Almeida, Milton M. Kanashiro

Publikováno v: Journal of Inorganic Biochemistry. 194:200-213

The synthesis, physico-chemical characterization, Density functional theory (DFT) calculation and cytotoxicity against five human tumoral cell lines (THP-1, U937, Molt-4, Colo205 and H460) of four new platinum(II) coordination compounds are reported,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b1f0adc17364a9034241902d66552d2
https://doi.org/10.1016/j.jinorgbio.2018.12.016

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Atrophic Proventriculitis Associated with Gravid Females of

Autor: Max R, Werneck, Hassan, Jerdy, Rachel B, Ribeiro, Mariah, Bianchi, Leide Laura Figueiredo, Maciel, João Carlos, de Aquino Almeida, Paula, Baldassin, Hugo, Gallo, Eulógio C Q, Carvalho

Publikováno v: The Journal of parasitology. 106(1)

The present study offers the first description of proventriculitis associated with the presence of gravid female nematodes of the genus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0a99ee18f55bf39a9061edacba0f6738
https://pubmed.ncbi.nlm.nih.gov/32083984

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Synthesis, characterization and antitumoral activity of new cobalt(II)complexes: Effect of the ligand isomerism on the biological activity of the complexes

Autor: Érika S. Bull, Samila R. Morcelli, João Carlos de Aquino Almeida, Adolfo Horn Junior, Adailton J. Bortoluzzi, Leide Laura Figueiredo Maciel, Rafaela Oliveira Moreira, Milton M. Kanashiro, Wagner da Silva Terra, Christiane Fernandes, Franz Viana Borges

Publikováno v: Journal of Inorganic Biochemistry. 161:73-82

The synthesis, physico-chemical characterization and cytotoxicity against five human tumoral cell lines (THP-1, U937, Molt-4, Colo205 and H460) of three new cobalt(II) coordination compounds are reported (i.e. Co(HL1)Cl (1), Co(HL2)Cl (2) and [Co(HL3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9e57c66daa7ba241d18b2b9a806eba
https://doi.org/10.1016/j.jinorgbio.2016.05.003

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In vitro and in vivo anti-proliferative activity and ultrastructure investigations of a copper(II) complex toward human lung cancer cell NCI-H460

Autor: Leide Laura Figueiredo Maciel, Christiane Fernandes, João Carlos de Aquino Almeida, Érika S. Bull, Adolfo Horn, Milton M. Kanashiro, William Rodrigues de Freitas

Publikováno v: Journal of Inorganic Biochemistry. 210:111166

The aim of our study was to evaluate the in vitro and in vivo anti-proliferative potential of complex (2) [Cu (L1)Cl]Cl.2H2O, where L1 = 1-[2-hydroxybenzyl(2-pyridylmethyl)amino]-3-(1-naphthyloxy)-2-propanol on lung carcinoma cell NCI-H460. Cell viab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edcb8d6f165c64f45953f817bef9ce56
https://doi.org/10.1016/j.jinorgbio.2020.111166

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Induction of apoptosis in leukemia cell lines by new copper(II) complexes containing naphthyl groups via interaction with death receptors

Autor: Jackson A. L. C. Resende, Franz Viana Borges, Gerhard Schenk, Bruna F. Lopes, Roberto Weider de Assis Franco, Adailton J. Bortoluzzi, Anderson B. Pires, Leide Laura Figueiredo Maciel, Nathália F. B. Azeredo, Adolfo Horn, João Carlos de Aquino Almeida, Milton M. Kanashiro, Christiane Fernandes, Bruno Szpoganicz, Érika S. Bull

Publikováno v: Journal of inorganic biochemistry. 153

The synthesis, physico-chemical characterization and cytotoxicity of four new ligands and their respective copper(II) complexes toward two human leukemia cell lines (THP-1 and U937) are reported (i.e. [(HL1)Cu(μ-Cl)2Cu(HL1)]Cl2·H2O (1), [(H2L2)Cu(�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac2f1c0e216e21ae4505214ab2c6debc
https://pubmed.ncbi.nlm.nih.gov/26485179

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