Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Leidan Zhang"'
Autor:
Jia Tang, Chenming Shang, Yue Chang, Wei Jiang, Jun Xu, Leidan Zhang, Lianfeng Lu, Ling Chen, Xiaosheng Liu, Qingjia Zeng, Wei Cao, Taisheng Li
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundUnbalanced inflammatory response is a critical feature of sepsis, a life-threatening condition with significant global health burdens. Immune dysfunction, particularly that involving different immune cells in peripheral blood, plays a cruci
Externí odkaz:
https://doaj.org/article/9d34143d6ea84657851f0ebe246fdc13
Autor:
Xiaolei Wang, Jiang Xiao, Leidan Zhang, Ying Liu, Na Chen, Meiju Deng, Chuan Song, Tingting Liu, Yuanyuan Zhang, Hongxin Zhao, Yanjie Yin
Publikováno v:
Chinese Medical Journal, Vol 136, Iss 18, Pp 2168-2177 (2023)
Abstract. Background:. Women comprise more than half of people living with human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) worldwide and incomplete immune recovery and metabolic abnormalities affect them deeply. Studies of
Externí odkaz:
https://doaj.org/article/73b9911d7775466597a137257b0fd949
Autor:
Xinyue Wang, Yuqing Wei, Zhijiao He, Di Wang, Leidan Zhang, Juan Du, Mengyuan Zhang, Meiqing Jiang, Na Chen, Meiju Deng, Bei Li, Chuan Song, Danying Chen, Huan Liu, Jiang Xiao, Hongyuan Liang, Hongxin Zhao, Yaxian Kong
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
Immune overactivation is a hallmark of chronic HIV infection, which is critical to HIV pathogenesis and disease progression. The imbalance of helper T cell (Th) differentiation and subsequent cytokine dysregulation are generally considered to be the
Externí odkaz:
https://doaj.org/article/493010d104484fc88e043758e9ea031a
Publikováno v:
BMC Psychiatry, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background Efavirenz (EFV)-induced neuropsychiatric toxicity bothers people living with HIV (PLHIV). Neuropsychiatric adverse effects of EFV may differ by length of time on EFV-based antiretroviral treatment (ART). Methods A cross-sectional,
Externí odkaz:
https://doaj.org/article/af7ee5c9e7ce4100b42a09c1f3eed52c
Publikováno v:
International Journal of Infectious Diseases, Vol 117, Iss , Pp 48-55 (2022)
Background: Efavirenz (EFV) 400 mg has been recommended to replace EFV 600 mg. There are only 200 mg and 600 mg dosage forms of EFV in China. Whether switching from one-tablet EFV 600 mg to two-tablet EFV 200 mg would weaken adherence or further affe
Externí odkaz:
https://doaj.org/article/5191498f31ae4737ab8a10f87c18b06a
Elevated Foxp3+ double-negative T cells are associated with disease progression during HIV infection
Autor:
Leidan Zhang, Yuqing Wei, Di Wang, Juan Du, Xinyue Wang, Bei Li, Meiqing Jiang, Mengyuan Zhang, Na Chen, Meiju Deng, Chuan Song, Danying Chen, Liang Wu, Jiang Xiao, Hongyuan Liang, Hongxin Zhao, Yaxian Kong
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Persistent immune activation, which occurs during the whole course of HIV infection, plays a pivotal role in CD4+ T cells depletion and AIDS progression. Furthermore, immune activation is a key factor that leads to impaired immune reconstitution afte
Externí odkaz:
https://doaj.org/article/dfc38439a7c046e68499cbcb638b78c7
Autor:
Xinyue Wang, Leidan Zhang, Juan Du, Yuqing Wei, Di Wang, Chuan Song, Danying Chen, Bei Li, Meiqing Jiang, Mengyuan Zhang, Hongxin Zhao, Yaxian Kong
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Although extensive use of antiretroviral therapy (ART) has made great progress in controlling HIV replication and improving CD4+ T cell recovery, the immune reconstitution remained insufficient in some patients, who were defined as poor immunological
Externí odkaz:
https://doaj.org/article/da4e337c912e4404be9d5a1969beffac
Autor:
Xinyue Wang, Di Wang, Juan Du, Yuqing Wei, Rui Song, Beibei Wang, Shuang Qiu, Bei Li, Leidan Zhang, Yongqin Zeng, Hongxin Zhao, Yaxian Kong
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Aging leads to functional dysregulation of the immune system, especially T cell defects. Previous studies have shown that the accumulation of co-inhibitory molecules plays an essential role in both T cell exhaustion and aging. In the present study, w
Externí odkaz:
https://doaj.org/article/90358f4a97c642fcbf40ab82ac8cc461
Publikováno v:
Journal of Interventional Cardiology, Vol 2022 (2022)
Objectives. We aimed to compare coronary risk factors, burden of coronary artery disease (CAD), and 1-year prognosis of people living with HIV (PLWH) and HIV-negative controls who underwent percutaneous coronary intervention (PCI) for acute coronary
Externí odkaz:
https://doaj.org/article/80a886ff2ed54246b4c98e8de471626f
Autor:
Ying Liu, Junyan Han, Xin Li, Danying Chen, Xuesen Zhao, Yaruo Qiu, Leidan Zhang, Jing Xiao, Bei Li, Hongxin Zhao
Publikováno v:
Vaccines, Vol 9, Iss 12, p 1458 (2021)
The administration of COVID-19 vaccines is the primary strategy used to prevent further infections by COVID-19, especially in people living with HIV (PLWH), who are at increased risk for severe symptoms and mortality. However, the vaccine hesitancy,
Externí odkaz:
https://doaj.org/article/fa80452fd7de4d92888e49dbcf7de94d