Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lei-Shu Wu"'
Publikováno v:
AAPS PharmSciTech. 1:5-9
Autor:
Lei-Shu Wu, Tom McCummings, Josephine Pang, Munir A. Hussain, Timothy J. McCormick, Rong-Kun Chang, Miriam Ramos
Publikováno v:
Pharmaceutical Research. 16:1136-1139
Evaluation of the disintegrant properties for an experimental, crosslinked polyalkylammonium polymer
Autor:
Michael Leonzio, Munir A. Hussain, Rong-Kun Chang, Lei-Shu Wu, Josephine Pang, Mirwais Shinwari
Publikováno v:
International Journal of Pharmaceutics. 173:87-92
The swelling and water sorption properties of an experimental, cross-linked polyalkylammonium polymer and three other super disintegrants, i.e. crospovidone, sodium starch glycolate, and croscarmellose sodium, were evaluated via water vapor uptake, w
Publikováno v:
Pharmaceutical Development and Technology. 1:43-49
The hygroscopicity of Brequinar sodium, an organ transplant immunosuppressant, at 75% relative humidity highly depends on the crystal form or crystallinity of the drug substance. Hygroscopicity and ease of water uptake of three lots of Brequinar sodi
Publikováno v:
Drug Development and Industrial Pharmacy. 17:67-76
There is a need for parenteral opioid analgesics with longer durations of action. Suspensions of nalbuphine were formulated by buffering the HCI salt to pH 9-9.2 in the presence of the commonly used suspending agents, methylcellulose, sodium carboxym
Publikováno v:
Journal of Pharmaceutical Sciences. 83:1404-1406
The antiarrhythmic agent moricizine hydrochloride exhibits a single melting-decomposition endotherm peak at temperatures ranging from 209 to 214.5 degrees C (Form I) when recrystallized from polar solvents, as determined by differential scanning calo
Publikováno v:
Pharmaceutical Research. 10:1793-1795
Publikováno v:
Pharmaceutical Research. :750-752
The nonopioid kappa agonist analgesic amine, DuP 747, as a hydrochloride salt exhibited an aqueous solubility of 3 mg/ml. This solubility was insufficient to provide the desired dose in a solution formulation for intramuscular administration. Aqueous
Autor:
Jian-Ge Chen, Jian-Ge (James) Chen, Debbie A. Markovitz, Amy Y. Yang, Shelley R. Rabel, Josephine Pang, Olga Dolinsky, Lei-Shu Wu, Mark Alasandro
Publikováno v:
Pharmaceutical development and technology. 5(4)
The purpose of this paper was to investigate the degradation chemistry of a fluoropyridinyl drug candidate in capsule formulation and to optimize the formulation based on a proposed degradation mechanism. Small developmental batches of capsules were
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 12(8)
A typical anhydrous moricizine hydrochloride, an antiarrhythmic agent, is a non-hygroscopic crystalline material. Three lots of moricizine hydrochloride were found to deliquesce within a day at 85% relative humidity, exhibit different X-ray powder di