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pro vyhledávání: '"Lei Young"'
Autor:
Lei Young
Covid-19 has become a pandemic and thousands of people are dying every day, yet we are still relying on 20th century technologies for treatment and prevention and don’t really have an effective cure for virus induced diseases. In this article I pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c0f12e8e5fa8bf347426eb5f6432198
https://doi.org/10.31219/osf.io/mh5eb
https://doi.org/10.31219/osf.io/mh5eb
Publikováno v:
Cell Mol Immunol
Publikováno v:
Molecular Microbiology. 85:669-683
Mycoplasma genitalium, a sexually transmitted human pathogen, encodes MgpB and MgpC adhesins that undergo phase and antigenic variation through recombination with archived 'MgPar' donor sequences. The mechanism and molecular factors required for this
Autor:
Nacyra Assad-Garcia, J. Craig Venter, Zhi-Qing Qi, Prashanth P. Parmar, Ray-Yuan Chuang, Clyde A. Hutchison, Mikkel A. Algire, Christopher H. Calvey, Hamilton O. Smith, Evgeniya A. Denisova, Vladimir N. Noskov, Monzia Moodie, Daniel G. Gibson, Chuck Merryman, Carole Lartigue, Li Ma, Radha Krishnakumar, Gwynedd A. Benders, Michael G. Montague, Cynthia Andrews-Pfannkoch, Lei Young, John I. Glass, Sanjay Vashee, Thomas H. Segall-Shapiro
Publikováno v:
Science
Science, American Association for the Advancement of Science, 2010, 329 (5987), pp.52-56. ⟨10.1126/science.1190719⟩
Science, American Association for the Advancement of Science, 2010, 329 (5987), pp.52-56. ⟨10.1126/science.1190719⟩
Let There Be Life The DNA sequence information from thousands of genomes is stored digitally as ones and zeros in computer memory. Now, Gibson et al. (p. 52 , published online 20 May; see the cover; see the Policy Forum by Cho and Relman ) have broug
Autor:
Vladimir N. Noskov, Cynthia Andrews-Pfannkoch, Hamilton O. Smith, Mikkel A. Algire, Timothy B. Stockwell, Holly Baden-Tillson, Chuck Merryman, Lei Young, Evgeniya A. Denisova, Daniel G. Gibson, J. Craig Venter, David W. Thomas, Jayshree Zaveri, Clyde A. Hutchison, Gwynedd A. Benders, Anushka Brownley, John I. Glass
Publikováno v:
Science. 319:1215-1220
We have synthesized a 582,970–base pair Mycoplasma genitalium genome. This synthetic genome, named M. genitalium JCVI-1.0, contains all the genes of wild-type M. genitalium G37 except MG408, which was disrupted by an antibiotic marker to block path
Publikováno v:
Limnology and Oceanography. 46:557-572
The bacterioplankton assemblage in Crater Lake, Oregon (U.S.A.), is different from communities found in other oxygenated lakes, as demonstrated by four small subunit ribosomal ribonucleic acid (SSU rRNA) gene clone libraries and oligonucleotide probe
Autor:
Hamilton O. Smith, Lei Young, J. Craig Venter, Clyde A. Hutchison, Ray-Yuan Chuang, Daniel G. Gibson
Publikováno v:
Nature Methods. 6:343-345
We describe an isothermal, single-reaction method for assembling multiple overlapping DNA molecules by the concerted action of a 5' exonuclease, a DNA polymerase and a DNA ligase. First we recessed DNA fragments, yielding single-stranded DNA overhang
Autor:
Vladimir N. Noskov, Isaac T. Yonemoto, Ray-Yuan Chuang, John I. Glass, Philip D. Weyman, Clyde A. Hutchison, Bogumil J. Karas, Ying-Chi Lin, Lei Young, Daniel G. Gibson, J. Craig Venter, Yo Suzuki, Cynthia Andrews-Pfannkoch, Jason Stam, Hamilton O. Smith
Publikováno v:
ACS synthetic biology. 1(7)
The ability to assemble large pieces of prokaryotic DNA by yeast recombination has great application in synthetic biology, but cloning large pieces of high G+C prokaryotic DNA in yeast can be challenging. Additional considerations in cloning large pi
Publikováno v:
Molecular microbiology. 85(4)
Mycoplasma genitalium, a sexually transmitted human pathogen, encodes MgpB and MgpC adhesins that undergo phase and antigenic variation through recombination with archived 'MgPar' donor sequences. The mechanism and molecular factors required for this
Autor:
Qihan Dong, Lei Young
Publikováno v:
Methods in Molecular Biology ISBN: 9781607616511
Site-directed mutagenesis is an invaluable tool for functional studies and genetic engineering. However, most current protocols require the target DNA to be cloned into a plasmid vector before mutagenesis can be performed, and none of them are effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::959930baa4c3e552dfb6aaef2f41b36e
https://doi.org/10.1007/978-1-60761-652-8_11
https://doi.org/10.1007/978-1-60761-652-8_11